Results 331 to 340 of about 5,633,974 (393)

Angiotensin-Converting Enzyme Inhibitors

Medical Clinics of North America, 1988
There is convincing evidence that ACE inhibitors, alone or in combination with a diuretic, effectively lower blood pressure in patients with all grades of essential or renovascular hypertension and that they are of particular benefit as adjunctive therapy in patients with congestive heart failure.
H H, Rotmensch, P H, Vlasses, R K, Ferguson   +2 more
openaire   +2 more sources

Substrate-Selective Enzyme Inhibitors

Trends in Pharmacological Sciences, 2019
Enzymes with multiple substrates pose a unique challenge for drug development because of an increased potential for on-target side effects. Maianti and colleagues (Nat. Chem. Biol., 2019) identify novel exo-site inhibitors with abilities to alter the substrate-selectivity of insulin-degrading enzymes (IDE).
Qian, Chu, Tina, Chang, Alan, Saghatelian   +2 more
openaire   +2 more sources

Preparation of a dual-enzyme co-immobilized capillary microreactor and simultaneous screening of multiple enzyme inhibitors by capillary electrophoresis.

Journal of Separation Science, 2013
A CE method based on a dual-enzyme co-immobilized capillary microreactor was developed for the simultaneous screening of multiple enzyme inhibitors. The capillary microreactor was prepared by co-immobilizing adenosine deaminase and xanthine oxidase on ...
Pingtan Lin, Shulin Zhao, Xin Lu, Fanggui Ye, Hengshan Wang   +4 more
semanticscholar   +1 more source

Angiotensin converting enzyme inhibitors

Pharmaceutisch Weekblad Scientific Edition, 1982
Inhibition of angiotensin converting enzyme (ACE) in patients suffering from renovascular hypertension results in lowering of the blood-pressure. The development of captopril, an orally active ACE inhibitor and the structure-activity relationship of captopril analogues are described.
openaire   +2 more sources

Angiotensin-Converting Enzyme Inhibitors

Medical Clinics of North America, 1987
In summary, ACE inhibitors are effective in reducing blood pressure as initial therapy in some hypertensive patients and in combination with diuretics and other agents in virtually all hypertensives. ACE inhibitors are uniquely advantageous because of their favorable hemodynamic effects, the lack of adverse metabolic effects, and their ability to ...
openaire   +2 more sources

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors.

Advances in Enzyme Regulation, 1984
T. Chou, P. Talalay
semanticscholar   +1 more source

Angiotensin-Converting Enzyme Inhibitors

AACN Advanced Critical Care, 1992
The angiotensin-converting enzyme (ACE) inhibitors available today include Captopril (Capoten), enalapril (Vasotec), enaloprilat (Vasotec IV), lisinopril (Prinivil, Zestril), benazepril (Lotensin), fosinopril (Monopril), and ramipril (Atace). These drugs are used in the treatment of hypertension and congestive heart failure.
openaire   +2 more sources

Enzyme-Inhibitors

Current Bioactive Compounds, 2006
  +4 more sources

Enzyme Inhibitors

Current Bioactive Compounds, 2005
  +4 more sources

Enzyme Inhibitors

Carbohydrate Polymers, 1983
Charles A. White, John F. Kennedy
openaire   +1 more source