Results 191 to 200 of about 882,535 (261)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Safety evaluation of the food enzyme endo-1,4-β-xylanase from the non-genetically modified <i>Trichoderma citrinoviride</i> strain TCLSC. [PDF]

EFSA J
EFSA Panel on Food Enzymes (FEZ), Zorn H, Baviera JMB, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Henrik Roos Y, Solano ML, Van Loveren H, Vernis L, Aguilera J, Andryszkiewicz M, Cavanna D, Kovalkovicova N, Liu Y.   +17 more
europepmc   +1 more source

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

Advanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya, Konda Reddy Kunduru, Krishanu Ghosal, Luna Rizik, Nofar Atari, Mahran Daifa, Neta Kutner, Bassma Khamaisi, Qi Wu, Simran Jindal, Merna Shaheen‐Mualim, Ranabir Majumder, Mahitosh Mandal, Michal Mandelboim, Shady Farah   +14 more
wiley   +1 more source

Enzymatic Production of Collagen Oligopeptides from Porcine Skin and Their Structure-Activity Relationships in Anti-Aging and Skin-Whitening Effect. [PDF]

Foods
Liang YY, Jiang HB, Xu SQ, Chen L, Cai ZH, Wang X, Bi GC, Xie J.   +7 more
europepmc   +1 more source

Disaccharidase Inhibitory Activity of Thai Plant Extracts. [PDF]

Nutrients
Kawami M, Yumoto R, Junyaprasert VB, Soonthornchareonnon N, Patanasethanont D, Sripanidkulchai B, Takano M.   +6 more
europepmc   +1 more source

Simple in vitro single-stranded linear and circular DNA preparation, functional selection, and validation using phosphor-derived modifications. [PDF]

J Biol Chem
Hamidi SV, Aguilar-Sánchez V, Héroux VL, Perreault J.   +3 more
europepmc   +1 more source

Isolation and Biophysical Characterization of Lipoxygenase-1 from Soybean Seed, a Versatile Biocatalyst for Industrial Applications. [PDF]

Biomolecules
Gerogianni I, Vardaxi A, Matis I, Karayianni M, Zoumpanioti M, Mavromoustakos T, Pispas S, Chrysina ED.   +7 more
europepmc   +1 more source