Results 201 to 210 of about 532,411 (388)

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

Impact of enzyme replacement therapy and hematopoietic stem cell transplantation in patients with Morquio A syndrome

Drug Design, Development and Therapy, 2015
Shunji Tomatsu,1,2 Kazuki Sawamoto,1 Carlos J Alméciga-Díaz,3 Tsutomu Shimada,1 Michael B Bober,1 Yasutsugu Chinen,4 Hiromasa Yabe,5 Adriana M Montaño,6 Roberto Giugliani,7 Francyne Kubaski,1,8 Eriko ...
Tomatsu S, Sawamoto K, Alméciga-Díaz CJ, Shimada T, Bober MB, Chinen Y, Yabe H, Montaño AM, Giugliani R, Kubaski F, Yasuda E, Rodríguez-López A, Espejo-Mojica AJ, Sánchez OF, Mason RW, Barrera LA, Mackenzie WG, Orii T   +17 more
doaj  

ENPP1 enzyme replacement therapy improves blood pressure and cardiovascular function in a mouse model of generalized arterial calcification of infancy [PDF]

, 2018
Tayeba Khan, Kerstin W. Sinkevicius, Sylvia Vong, Arlen Avakian, Markley C. Leavitt, Hunter F. Malanson, Andre J. Marozsan, Kim L. Askew   +7 more
openalex   +1 more source

European consensus for starting and stopping enzyme replacement therapy in adult patients with Pompe disease: a 10‐year experience

European Journal of Neurology, 2017
A. Ploeg, M. Kruijshaar, A. Toscano, P. Laforêt, C. Angelini, R. Lachmann, S. I. Pascual, S. I. P. Pascual, M. Roberts, K. Rösler, T. Stulnig, P. Doorn, P. V. D. Bergh, J. Vissing, Benedikt Schoser   +14 more
semanticscholar   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

AB126. Enzyme replacement therapy in patient with mucopolysaccharidosis type I: a case report

, 2015
Ngoc Thi Bich Can, Dũng Chí Vũ, Hang Thi Thuy Le, Khanh Ngoc Nguyen, Huong Thi Bui   +4 more
openalex   +2 more sources

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

Advanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang, Shuang Feng, Jie Luo, Kaige Xu, Junfeng Guo, Xingyue Zhang, Mengxue Yuan, Qiang Luo, Yu Huang, Chaoqiang Fan, Kibret Mequanint, Donghui Zhu, Malcolm Xing, Shiming Yang   +13 more
wiley   +1 more source

Recommendation for diagnosis and treatment of fabry’s disease in Slovenia

Zdravniški Vestnik, 2006
Background: Fabry disease is a rare X-chromosome linked disease. Due to gene mutation, activity of enzyme α galactosidase A is lowered or absent and sphingolipids are deposited in different organ cells.
Bojan Vujkovac, Mišo Šabovič, Franc Verovnik, Davorin Benko, Andreja Cokan, Milan Špegel, Jožica Kotnik, Franc Kotnik, Ivo Rubin, Derralyn A. Hughes   +9 more
doaj  

Enzyme replacement therapy during pregnancy and breastfeeding in late-onset Pompe disease. [PDF]

Int Breastfeed J
Bachmann M, Kasper D, Scholl-Bürgi S, Margreitter J, Höller A, Löscher W, Karall D, Zöggeler T.   +7 more
europepmc   +1 more source

Is There Need for Pancreatic Enzyme Replacement Therapy in Patients with Exocrine Pancreatic Insufficiency When Using High-Caloric Liquid Diets? Orientating Studies on Praecaecal Digestibility in Pigs with Experimentally Induced Pancreatic Exocrine Insufficiency and Ileocaecal Fistula [PDF]

Anne Mößeler, Annette Liesegang, Paul R. Torgerson, Josef Kamphues   +3 more
openalex   +1 more source