Results 261 to 270 of about 249,219 (350)

Xeno‐Free Biocompatible Peptide‐Based Bioinks Reinforced with Cellulose Nanofibers for 3D Printing

Advanced Healthcare Materials, EarlyView.
A xeno‐free bioink combining self‐assembled peptides and cellulose nanofibers is developed for 3D printing. The bioink forms a non‐cross‐linked 3D scaffold, mimicking the extracellular matrix and supporting over 95% cell viability. This approach offers enhanced biocompatibility and mechanical stability, advancing 3D printing for personalized medicine ...
Francesca Netti, Mor Tsuriano, Noam Rattner, Vania Altobelli, Yoav Dan, Lihi Adler‐Abramovich   +5 more
wiley   +1 more source

Novel transferrin receptor-mediated enzyme replacement therapy efficiently treats myogenic and neurogenic aspects of Pompe disease in mice. [PDF]

Mol Ther Methods Clin Dev
George K, Riley R, Zhou S, Allen E, Smith L, Kistanova E, Kinton S, Guo L, Bangari D, Ismail A, Thummapudi J, Boumezbeur F, Selingue E, Tamarelle D, Capdevila C, Do TM, Lesuisse D, Leksa N, Sardi P, van der Flier A.   +19 more
europepmc   +1 more source

Persistent bone disease in adult type 1 Gaucher disease despite increasing doses of enzyme replacement therapy

, 2008
Maaike de Fost, C. J. M. van Noesel, Johannes M. F. G. Aerts, Mario Maas, Ruud G. Pöll, Carla E. M. Hollak   +5 more
openalex   +2 more sources

Microencapsulation of Histidase for Enzyme Replacement Therapy

Journal of Pharmacy and Pharmacology, 1979
T. L. Whateley, Alexander T. Florence, D A Wood   +2 more
openaire   +2 more sources

Liver transplantation and portacaval shunt in genetic diseases [PDF]

, 1982
Starzl, TE
core  

Human Endometrial Extracellular Matrix Hydrogel Facilitated Endometrial Mesenchymal Stem Cells for Endometrial Regeneration

Advanced Healthcare Materials, EarlyView.
Adequate thickness of the uterine lining is crucial for women with thin or damaged endometrium to achieve pregnancies. Endometrial mesenchymal stem cells (eMSC) can facilitate the cyclical repair and regeneration of the human endometrium. In this study, the human endometrium derived extracellular matrix hydrogel supports the growth of eMSC promoting ...
Jingwen Xu, Philip C N Chiu, Ernest H Y Ng, Sentao Hu, Zi Ye, Liaobing Xin, Lie Ma, Songying Zhang, William S B Yeung, Rachel W S Chan   +9 more
wiley   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

Targeted nanoliposomes to improve enzyme replacement therapy of Fabry disease. [PDF]

Sci Adv
Tomsen-Melero J, Moltó-Abad M, Merlo-Mas J, Díaz-Riascos ZV, Cristóbal-Lecina E, Soldevila A, Altendorfer-Kroath T, Danino D, Ionita I, Pedersen JS, Snelling L, Clay H, Carreño A, Corchero JL, Pulido D, Casas J, Veciana J, Simó Schwartz Jr, Sala S, Font A, Birngruber T, Royo M, Córdoba A, Ventosa N, Abasolo I, González-Mira E.   +25 more
europepmc   +1 more source

Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions

Advanced Healthcare Materials, EarlyView.
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang, Bárbara B. Mendes, Dhruv Menon, Jhenifer Oliveira, Xu Chen, Fatma Demir Duman, João Conniot, Sergio Mercado, Xiewen Liu, Shi‐Yuan Zhang, João Conde, Rachel E. Hewitt, David Fairen‐Jimenez   +12 more
wiley   +1 more source

Clinical manifestations in Egyptian Pompe disease patients: Molecular variability and enzyme replacement therapy (ERT) outcomes. [PDF]

Ital J Pediatr
Hussein MA, ElTaher H, Mahmoud R, Sobh D, Al-Haggar M.   +4 more
europepmc   +1 more source