Results 231 to 240 of about 2,217,916 (339)
Blocking the shikimate pathway amplifies the impact of carvacrol on biofilm formation in <i>Candida albicans</i>. [PDF]
Molaeitabari A, Dahms TES.
europepmc +1 more source
A Feedback Loop Between Fatty Acid Metabolism and Epigenetics in Clear Cell Renal Carcinoma
The current study has profiled the landscape of active enhancers in ccRCC and identified FABP5 as an oncogene. FABP5 is essential for the lipid droplet formation driven by HIFs and critical for H3K27ac and enhancer activity. The study has discovered the function of a feedback loop between epigenetics and lipid metabolism regulated by FABP5 in ccRCC ...
Zhou Ye+21 more
wiley +1 more source
The DNA Topoisomerase 1 Contributes to Stress Response in <i>Saccharomyces cerevisiae</i>, Regardless Its Catalytic Activity. [PDF]
D'Alfonso A+3 more
europepmc +1 more source
Neural precursor cell expressed developmentally down‐regulated gene 4‐like (NEDD4L) prevents colorectal cancer liver metastasis through ubiquitination and degradation of protein arginine methyltransferase 5 (PRMT5). PRMT5 degradation attenuates the methylarginine of AKT1.
Zhewen Dong+8 more
wiley +1 more source
The bvr locus of Listeria monocytogenes mediates virulence gene repression by beta-glucosides [PDF]
Brehm, Klaus+3 more
core
The nanosized covalent organic polymer composed of photosensitizer porphyrin, pyruvate kinase inhibitor vitamin K3, and STAT3 inhibitor WP1066 is prepared for enhanced photodynamic immunotherapy by simultaneous hypoxia relief and STAT3 inhibition. Abstract Photodynamic therapy (PDT) is a promising cancer therapy modality by generating reactive oxygen ...
Lei Lei+7 more
wiley +1 more source
COORDINATE REPRESSION OF THE SYNTHESIS OF FOUR HISTIDINE BIOSYNTHETIC ENZYMES BY HISTIDINE
Bruce N. Ames, Barbara Garry
openalex +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen+6 more
wiley +1 more source
CRISPRi-assisted metabolic engineering of cyanobacteria for photosynthetic hyaluronic acid from CO<sub>2</sub>. [PDF]
Son J, Lee HJ, Woo HM.
europepmc +1 more source