Results 121 to 130 of about 3,038,812 (378)
Electrodes modified with lipid membranes to study quinone oxidoreductases
, 2009 Quinone oxidoreductases are a class of membrane enzymes that catalyse the oxidation or reduction of membrane-bound quinols/quinones. The conversion of quinone/quinol by these enzymes is difficult to study because of the hydrophobic nature of the enzymes ...
Jeuken, LJC, Weiss, SA
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How an Enzyme Can Be a Non-Enzyme [PDF]
Structure, 2004 AbstractThe crystal structure of the endonuclease, ribonuclease III, in complex with a double-stranded RNA fragment reveals the mechanism that allows for switching between two functional forms of the enzyme.
openaire +4 more sources
FEBS Letters, EarlyView.Most MmpLs transport lipids and glycolipids of the complex mycomembrane of mycobacteria. This study shows that MmpL10 from Mycobacterium smegmatis, the transporter of the trehalose polyphosphate precursor, harbors a coiled‐coil‐like extension. Biochemical and electron microscopy studies demonstrate that the coiled‐coil enables MmpL10 to trimerize.
Julie Couston +7 more
wiley +1 more source
Microbial Cell FactoriesBackground Seven-carbon sugars, which rarely exist in nature, are the key constitutional unit of septacidin and hygromycin B in bacteria. These sugars exhibit a potential therapeutic effect for hypoglycaemia and cancer and serve as building blocks for ...
Yinlu Liu +8 more
doaj +1 more source
Functional and structural mimics of superoxide dismutase enzymes [PDF]
, 2008 Superoxide dismutase (SOD) enzymes form important defence line in living organisms. Through a dismutation reaction they transform the highly reactive superoxide radical ion to oxygen and hydrogen peroxide.
Pálinkó, István
core
Enzyme‐enzyme interactions and their metabolic role
FEBS Letters, 1990 There are continuing reports on the existence of complexes of sequential metabolic enzymes. New techniques for their detection have been described and include affinity electrophoresis and the use of anti‐idiotypic antibodies. Channeling of substrates has been reported for several systems as well as direct substrate transfer through dynamic enzyme ...
Paul A. Srere, Judit Ovádi
openaire +2 more sources
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
eLife, 2019 Coordination of the cellular response to DNA damage is organised by multi-domain ‘scaffold’ proteins, including 53BP1 and TOPBP1, which recognise post-translational modifications such as phosphorylation, methylation and ubiquitylation on other proteins ...
Nicolas Bigot +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
ENZYME INDUCTION AS AN ALL-OR-NONE PHENOMENON [PDF]
, 1957 Aaron Novick, Milton A. Weiner
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