Results 251 to 260 of about 1,930,061 (319)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Spatiotemporal dynamics of reactive oxygen species: implications for cellular homeostasis and redox therapies. [PDF]

Cell Mol Biol Lett
Li Y, Zhao Q, Hu H, Pei JF.
europepmc   +1 more source

Microfluidic Magnetic Droplet-Based Chemiluminescence Enzyme Immunoassay for Multiplex Sepsis Biomarkers Screening

Jiayue Huang, Jinbo Li, Xin Yang, Lexiang Zhang, Feika Bian, Dan Hu   +5 more
openalex   +1 more source

Fibrinogen Changes Before and After Intravenous Thrombolysis as Predictors of Cerebral Injury and Clinical Outcomes in Acute Ischemic Stroke: A Multicenter Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma fibrinogen is essential in thrombosis and fibrinolysis, yet its dynamic changes pre‐ and post‐intravenous thrombolysis (IVT) for predicting brain injury severity and prognosis in acute ischemic stroke (AIS) patients remain unclear.
Wenhai Zhai, Yang Qu, Reziya Abuduxukuer, Kejia Zhang, Peng Zhang, Xin Tang, Huaimei Zhang, Lijuan Wang, Lichong Yang, Shuangxu Tan, Zhimei Yuan, Ce Han, Lili He, Yuping Zheng, Fenglan Zhao, Lijie Guo, Ligang Jiang, Jinfeng Li, Yongfei Jiang, Xuexia Zou, Dan Xu, Han Xu, Xiaojia Wang, Yingbin Qi, Xuefeng Hu, Yu Zhang, Zhen‐Ni Guo, Hang Jin, on behalf of the Biomarkers of Brain Injury Investigator Study Group   +28 more
wiley   +1 more source

THE INFLUENCE OF NUTRITION ON THE FORMATION OF PANCREATIC ENZYME SECRETION AND HOMEOSTASIS IN RATS OF DIFFERENT AGES DURING POSTNATAL ONTOGENESIS

Mullajonova Nigoraxon Maxmudovna, Qodirov Shokir Qodirovich, Mullajonova Nigoraxon Makhmudovna, Kodirov Shokir Kodirovich   +3 more
openalex   +1 more source

Computational dataset for in-silico identification of multitarget natural product scaffolds targeting key enzymes across Mycobacterium species

Ruchi Nair
openalex   +1 more source

Evaluation of the enzyme paraoxonase type 1 in the seminal plasma and its mRNA expression in boars gonadal tissue

, 2016
Matheus Schardong Lucca
openalex   +1 more source

Acute effect of ketoanalogue and amino acid supplementation on blood ammonia, enzymes biomarkers of muscle damage an white bloo cells counts in cyclists undergoing physical exercise under low heat stress environment

, 2015
Rafaela Carvalho Pereira Lima
openalex   +1 more source

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Superefficient enzymes

Cellular and Molecular Life Sciences, 2001
Diffusion-controlled enzymes are characterized by second-order rate constants in the range 10(8)-10(10) M(-1)s(-1). These values are at the upper end of the observed rates of many enzyme-substrate reactions and have been predicted by theoretical studies on bimolecular reaction in solution.
Stroppolo, ME, FALCONI, MATTIA, CACCURI, ANNA MARIA, DESIDERI, ALESSANDRO   +3 more
openaire   +3 more sources

Hybrid enzymes: manipulating enzyme design

Trends in Biotechnology, 1998
Hybrid enzymes are engineered to contain elements of two or more enzymes. Hybrid-enzyme approaches, by taking advantage of the vast array of enzymatic properties that nature has evolved, as well as the strategies that nature has used to evolve them, are becoming an increasingly important avenue for obtaining novel enzymes with desired activities and ...
A E, Nixon, M, Ostermeier, S J, Benkovic
openaire   +2 more sources