Carrier-Free Enzyme Immobilization for High-Density Catalytic Architectures in Flow Biocatalysis. [PDF]
Stalter SP, Rabe KS, Niemeyer CM.
europepmc +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Extrusion and enzyme addition enhanced ileal and total tract digestibility of pulse-based diets fed to growing pigs. [PDF]
Van Straten WPG +5 more
europepmc +1 more source
Clinical Validation of Plasma p‐217tau in Neurological Diseases
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
Safety evaluation of an extension of use of the food enzyme glucan 1,4-α-maltohydrolase from a genetically modified <i>Bacillus licheniformis</i> strain NZYM-SD. [PDF]
EFSA Panel on Food Enzymes (FEZ) +15 more
europepmc +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Enhanced fibrinolytic enzyme production by Oidiodendron maius through green bioprocessing of agro-industrial residue. [PDF]
Sajid H, Iqbal M, Gull-E-Faran.
europepmc +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
A fast workflow to explore active enzymes from environmental samples through functional metagenomics. [PDF]
Muammar A +5 more
europepmc +1 more source

