Results 111 to 120 of about 740,420 (312)

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Validated spectrofluorimetric method for determination of cyproheptadine in pharmaceutical formulation and human plasma. Application to content uniformity test

open access: yesResults in Chemistry
Cyproheptadine is a first generation antihistaminic drug which has several pharmacological effects includes anesthetic, antiserotonergic and anticholinergic properties.
Mahmoud A. Omar   +4 more
doaj   +1 more source

Mg/Al HYDROTALCITE-LIKE SYNTHESIZED FROM BRINE WATER FOR EOSIN YELLOW REMOVAL

open access: yesIndonesian Journal of Chemistry, 2011
Attempts to synthesis of Mg/Al HTlc using magnesium from several raw material resources are widely investigated. One of raw material would purpose as source of magnesium to synthesis of Mg/Al HTlc is brine water which is well known as the desalination ...
Eddy Heraldy   +3 more
doaj   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao   +8 more
wiley   +1 more source

Covalent bonding of polycations to small polymeric particles [PDF]

open access: yes, 1975
Process produces small spherical polymeric particles which have polycations bound to them. In emulsion form, particles present large positively charged surface which is available to absorb polyanions.
Rembaum, A.
core   +1 more source

Germanane Quantum Dots Promote Metabolic Reprogramming of Immune Cells Toward Regulatory T Cells and Suppress Inflammation In Vitro and In Vivo

open access: yesAdvanced Functional Materials, EarlyView.
Metabolic changes in immune cells direct the phenotype and function of the host immune system. Smart nanomaterials must target metabolic pathways to direct immune cell fate. This study reports the fabrication and first application of germanane quantum dots (GeHQDs) to modulate inflammation in vitro and in vivo.
Abhay Srivastava   +7 more
wiley   +1 more source

Photophysical and antibacterial activity of light-activated quaternary eosin Y

open access: yesOpen Chemistry, 2019
The functional characteristics of a new eosin dye with biocidal quaternary ammonium group (E) were studied in aqueous solution and in organic solvents of different polarity.
Staneva Desislava   +4 more
doaj   +1 more source

Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment

open access: yesAdvanced Functional Materials, EarlyView.
Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li   +12 more
wiley   +1 more source

Application of two staining methods for sperm morphometric evaluation in domestic pigs

open access: yesJournal of Veterinary Research, 2017
Introduction: The effect of two smear staining methods on the dimensions and shape of sperm cells in the semen of domestic pigs was evaluated. Material and Methods: The studies were carried out on 30 ejaculates collected from 15 boars, which included ...
Kondracki Stanisław   +3 more
doaj   +1 more source

Ionic‐Electronic Hydrogel‐Liquid Metal Composite Bilayer with Tissue‐Adaptive and Adhesive Properties for Closed‐Loop Neuroprosthetic System

open access: yesAdvanced Functional Materials, EarlyView.
A hydrogel–liquid metal composite peripheral nerve interface (HLB‐PNI) combines electrically durable electrodes and tissue‐adhesive hydrogel for tissue‐adaptive implantation. In nerve‐injured rats, it enables the diagnosis of sensory‐motor connectivity via stimulation and neural signal recording.
Yewon Kim   +5 more
wiley   +1 more source

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