Results 161 to 170 of about 186,812 (342)

Immunological Profiling suggests an Association between Treg dysfunction and Pain in Knee Osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Background Pain is the hallmark symptom of osteoarthritis (OA) and its biological drivers remain poorly understood. While the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular regulatory T cells (Tregs), is not well understood. Methods We performed omics profiling of peripheral blood from 46
Marie Binvignat, Johanna Dubois, Maria Marco Salvador, Paul Stys, Fabien Pitoiset, Alexandra Roux, Michèle Sastre, Signe Hassler, Roberta Lorenzon, Claire Ribet, Vanessa Mhanna, Hélène Vantomme, Leslie Adda, Pierre Barennes, Nicolas Coatnoan, Kenz Le Gouge, Caroline Aheng, Alice Courties, Lise Minssen, Atul J. Butte, Adrien Six, Michelle Rosenzwajg, Nicolas Tchitchek, Francis Berenbaum, David Klatzmann, Encarnita Mariotti‐Ferrandiz, Jérémie Sellam   +26 more
wiley   +1 more source

Dupilumab in persistent asthma with elevated eosinophil levels.

New England Journal of Medicine, 2013
S. Wenzel, L. Ford, D. Pearlman, S. Spector, L. Sher, F. Skobieranda, Lin Wang, S. Kirkesseli, R. Rocklin, Brian Bock, J. Hamilton, J. Ming, A. Radin, N. Stahl, G. Yancopoulos, N. Graham, G. Pirozzi   +16 more
semanticscholar   +2 more sources

Single-Use Autoinjector Functionality And Reliability For At-Home Administration Of Benralizumab For Patients With Severe Asthma: GRECO Trial Results

Journal of Asthma and Allergy, 2019
Gary T Ferguson,1 Jeremy Cole,2 Magnus Aurivillius,3 Paul Roussel,4 Peter Barker,4 Ubaldo J Martin4 On behalf of the GRECO study investigators1Pulmonary Research Institute of Southeast Michigan, Farmington Hills, MI, USA; 2OK Clinical Research, LLC,
Ferguson GT, Cole J, Aurivillius M, Roussel P, Barker P, Martin UJ   +5 more
doaj  

Colonic left‐side increase of eosinophils: a clue to drug‐related colitis in adults [PDF]

, 2008
Giovanni Casella, Vincenzo Villanacci, Simona Fisogni, A. Cambareri, Camillo Di Bella, Nadia Corazzi, Seema Rao Gorla, Vittorio Baldini, Gabrio Bassotti   +8 more
openalex   +1 more source

Comprehensive characterization of central BCL-2 family members in aberrant eosinophils and their impact on therapeutic strategies [PDF]

, 2021
Timo O. Odinius, Lars Buschhorn, Celina Wagner, Richard Hauch, Veronika Dill, Marta Dechant, Michèle C. Buck, Khalid Shoumariyeh, Philipp Moog, Juliana Schwaab, Andreas Reiter, Knut Brockow, Katharina S. Götze, Florian Bassermann, Ulrike Höckendorf, Caterina Branca, Philipp J. Jost, Stefanie Jilg   +17 more
openalex   +1 more source

Exosomes from eosinophils autoregulate and promote eosinophil functions

Journal of Leukocyte Biology, 2017
J. Cañas, B. Sastre, C. Mazzeo, M. Fernández‐Nieto, J. Rodrigo-Muñoz, A. González-Guerra, M. Izquierdo, P. Barranco, S. Quirce, J. Sastre, V. Pozo   +10 more
semanticscholar   +1 more source

Molecular stratification of antiphospholipid syndrome through integrative analysis of the whole‐blood RNA transcriptome

Arthritis &Rheumatology, Accepted Article.
Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati, Feiyang Ma, Katarina Kmetova, Sherwin Navaz, Claire K. Hoy, Cyrus Sarosh, Ajay Tambralli, Erika Navarro‐Mendoza, Johann E. Gudjonsson, J. Michelle Kahlenberg, Jacqueline A. Madison, Alí Duarte‐García, Jason S. Knight, Yu Zuo   +13 more
wiley   +1 more source

Cutting Edge: Serotonin Is a Chemotactic Factor for Eosinophils and Functions Additively with Eotaxin [PDF]

, 2004
Stefen A. Boehme, Francisco M. Lio, Lyudmila Sikora, Terlika S. Pandit, Karine Lavrador, P. Sriramarao, P. Sriramarao   +6 more
openalex   +1 more source

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Usefulness of White Blood Cell Differential-based Indices in Patients With Extensive-stage Small Cell Lung Cancer. [PDF]

Cancer Diagn Progn
Nakao M, Kuriyama M, Gomyo R, Hasegawa M, Hayashi S, Takeda N, Muramatsu H.   +6 more
europepmc   +1 more source