Results 31 to 40 of about 23,268 (212)

Functional 2D Nanoplatforms Alleviate Eosinophilic Chronic Rhinosinusitis by Modulating Eosinophil Extracellular Trap Formation

Advanced Science
The therapeutic outcomes of patients with eosinophilic chronic rhinosinusitis (ECRS) remain unsatisfactory, largely because the underlying mechanisms of eosinophilic inflammation are uncertain. Here, it is shown that the nasal secretions of ECRS patients
Zhaoxu Tu, Ming Liu, Changyi Xu, Yi Wei, Tong Lu, Yongqiang Xiao, Hongxia Li, Shuaiyin Zhang, Xinran Xie, Jian Li, Weiping Wen   +10 more
doaj   +3 more sources

Kaempferol as a multifaceted immunomodulator: implications for inflammation, autoimmunity, and cancer [PDF]

Frontiers in Immunology
Kaempferol (KMF) is a dietary flavonoid exhibiting profound immunomodulatory effects across multiple immune cell populations. This review synthesizes current insights into how KMF regulates diverse immune cell populations and its therapeutic potential in
Han Dong, Han Dong, Ge Song, Zhe Wang, Xue Wu, Qi Wang, Yue-Hui Wang   +6 more
doaj   +2 more sources

Eosinophil Secretion of Granule-Derived Cytokines [PDF]

, 2014
Eosinophils are tissue-dwelling leukocytes, present in the thymus, and gastrointestinal and genitourinary tracts of healthy individuals at baseline, and recruited, often in large numbers, to allergic inflammatory foci and sites of active tissue repair ...
Bonjour, Kennedy, Melo, Rossana C. N., Spencer, Lisa A., Weller, Peter F.   +3 more
core   +16 more sources

Possible clinical implication of eosinophil extracellular traps in eosinophilic otitis media [PDF]

Otorhinolaryngology-Head and Neck Surgery, 2019
N. Ohta, S. Ueki, M. Hirokawa, Sachiko Tomioka-Matsutani, T. Kawano, T. Miyasaka, Tomoko Takahashi, Yutaka Nakamura, I. Ohno, S. Fujieda   +9 more
semanticscholar   +2 more sources

Involvement of peptidylarginine deiminase 4 in eosinophil extracellular trap formation and contribution to citrullinated histone signal in thrombi [PDF]

Journal of Thrombosis and Haemostasis
Background: Extracellular traps formed by neutrophils (NETs) and eosinophils (EETs) have been described in coronary thrombi, contributing to thrombus stability.
Crescente, Marilena, Denorme, Frederik, Glatz, Katharina, Grandhi, Ramesh, Martinod, Kimberly, Meyers, Severien, Siegel, Patrick M, Stroobants, Mathias, Van Bruggen, Stijn, Witsch, Thilo   +9 more
core   +2 more sources

Eosinophil extracellular traps: mechanisms of formation, functions

Immunopathology, Allergology, Infectology, 2019
E. Minina, P. Novikov
semanticscholar   +3 more sources

Cellular and molecular features of asthma mucus plugs provide clues about their formation and persistence [PDF]

The Journal of Clinical Investigation
BACKGROUND Mucus plugs form in acute asthma and persist in chronic disease. Although eosinophils are implicated in mechanisms of mucus pathology, many mechanistic details about mucus plug formation and persistence in asthma are unknown.METHODS Using ...
Maude A. Liegeois, Aileen Hsieh, May Al-Fouadi, Annabelle R. Charbit, Chen Xi Yang, Tillie-Louise Hackett, John V. Fahy   +6 more
doaj   +2 more sources

Distinct functions of eosinophils in severe asthma with type 2 phenotype: clinical implications [PDF]

The Korean Journal of Internal Medicine, 2020
Asthma is commonly recognized as a heterogeneous condition with a complex pathophysiology. With advances in the development of multiple medications for patients with asthma, most asthma symptoms are well managed.
Youngwoo Choi, Soyoon Sim, Hae-Sim Park
doaj   +1 more source

Calcium ionophore-activated platelets induce eosinophil extracellular trap formation

Allergology International, 2023
Platelets play a modulatory role in inflammatory response by secreting a vast array of granules and disintegrating into membrane-bound microparticles upon activation. The interplay between eosinophils and platelets is postulated to be implicated in the pathology of allergic airway inflammation. In this study, we investigated whether activated platelets
Myeong Seong Sim, Hye Jeong Kim, Ikhyeon Bae, Chun Kim, Hun Soo Chang, Youngwoo Choi, Dong-Hyun Lee, Hae-Sim Park, Il Yup Chung   +8 more
openaire   +3 more sources

Structural and Signaling Events Driving Aspergillus fumigatus-Induced Human Eosinophil Extracellular Trap Release

Frontiers in Microbiology, 2021
Eosinophils are granulocytes classically involved in allergic diseases and in the host immune responses to helminths, fungi, bacteria and viruses.
Marina Valente Barroso, Marina Valente Barroso, Isabella Gropillo, Marcella A. A. Detoni, Glaucia A. Thompson-Souza, Valdirene S. Muniz, Claudia Regina Isaías Vasconcelos, Rodrigo T. Figueiredo, Rossana C. N. Melo, Josiane S. Neves   +9 more
doaj   +1 more source