Results 61 to 70 of about 23,268 (212)
The Immune System Throws Its Traps: Cells and Their Extracellular Traps in Disease and Protection
Cells, 2021 The first formal description of the microbicidal activity of extracellular traps (ETs) containing DNA occurred in neutrophils in 2004. Since then, ETs have been identified in different populations of cells involved in both innate and adaptive immune ...
Fátima Conceição-Silva +6 more
doaj +1 more source
Mounting a specific immune response increases energy expenditure of the subterranean rodent Ctenomys talarum (tuco-tuco): Implications for intraspecific and interspecific variation in immunological traits [PDF]
, 2010 It was recently hypothesised that specific induced defences, which require substantial time and resources and are mostly beneficial against repeated infections, are more likely to be favoured in 'slow-living-pace' species.
Antenucci, Carlos Daniel +3 more
core +1 more source
Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways [PDF]
Journal of Allergy and Clinical Immunology, 2011 Asthma is a heterogeneous inflammatory airway disorder that involves eosinophilic and noneosinophilic phenotypes. Unlike in healthy lungs, eosinophils are often present in atopic asthmatic airways, although a subpopulation of asthmatic subjects predominantly experience neutrophilic inflammation.
Dworski Ryszard +3 more
openaire +2 more sources
Macrophage Extracellular Traps in Immunity and Cancer
Advanced Science, EarlyView.As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Four aspiration methods (UV, IN, IT, and OA) were compared, and OA was identified as the most effective delivery technique. A chronic aspiration pneumonia model was then established through repeated OA of food suspension or gastric contents. Integrated analyses, including micro‐CT, histopathology, cytokine profiling, and RNA sequencing, revealed ...
Qianwen Li +4 more
wiley +1 more source
An unusual case of eosinophilic lung disease with multiple cyst formation
Respiratory Medicine Case Reports, 2020 We report here an unusual case of eosinophilic necrotizing inflammation of the lung that mimicked chronic eosinophilic pneumonia. A 71-year-old man who lived in an unsanitary environment and was referred to our hospital with suspected pneumonia ...
Hitomi Nogawa +8 more
doaj +1 more source
Lectin receptors expressed on myeloid cells [PDF]
, 2016 Lectins recognize a diverse array of carbohydrate structures and perform numerous essential biological functions. Here we focus on only two families of lectins, the Siglecs and C-type lectins.
Brown, Gordon D., Crocker, Paul R.
core +2 more sources
International Journal of Molecular Sciences, 2023 Chronic rhinosinusitis (CRS) is characterized by inflammatory cell infiltration in the sinonasal mucosa. Eosinophil and neutrophil extracellular traps (EETs and NETs, respectively) are prominently found in CRS. This study aimed to investigate the effect of airborne fungi, Alternaria alternata and Aspergillus fumigatus, on EET and NET formation.
Seung-Heon Shin +4 more
openaire +2 more sources
Arthritis &Rheumatology, EarlyView.Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley +1 more source
Alzheimer's Amyloid-β is an Antimicrobial Peptide: A Review of the Evidence [PDF]
, 2018 The final publication is available at IOS Press through http://dx.doi.org/10.3233/JAD-171133.The amyloid-β (Aβ) peptide has long been considered to be the driving force behind Alzheimer’s disease (AD).
Brothers, Holly +2 more
core +1 more source