Results 61 to 70 of about 59,014 (262)

Cenobamate use in super‐refractory status epilepticus: A report of three cases

open access: yesEpileptic Disorders, EarlyView.
Abstract Objectives Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...
Marina Romozzi   +11 more
wiley   +1 more source

Endometrial Stromal Sarcoma–Associated Hypereosinophilia: A Case Report

open access: yesCase Reports in Oncological Medicine
Eosinophilia is a common systemic reaction to allergy, parasitic infection, or drug hypersensitivity. Rarely, it manifests as a paraneoplastic phenomenon, most commonly secondary to hematologic malignancies or extensive metastatic disease in solid tumors.
Smriti Nair   +7 more
doaj   +1 more source

Unraveling the diagnostic puzzle of eosinophilia in children

open access: yesGlobal Pediatrics
Eosinophilia is characterized by an increased eosinophil count in peripheral blood, and presents diagnostic challenges in children. Clinical manifestations can range from mild to severe, necessitating a nuanced understanding of its causes and management ...
Elena Chiappini
doaj   +1 more source

Real‐world use of Cenobamate in pediatric drug‐resistant epilepsy: A European multicenter retrospective study

open access: yesEpilepsia Open, EarlyView.
Abstract Pediatric drug‐resistant epilepsy (DRE) remains a significant clinical challenge, with few effective pharmacological options. This European multicenter retrospective study assessed the real‐world efficacy, tolerability, and retention of off‐label cenobamate (CNB) in 108 children and adolescents with DRE (median age: 13.83 years, range 3.9–19.8)
Konstantin L. Makridis   +14 more
wiley   +1 more source

Endomyocardial involvement in asymptomatic Latin American migrants with eosinophilia related to helminth infection: A pilot study.

open access: yesPLoS Neglected Tropical Diseases
BackgroundHypereosinophilic syndrome can produce cardiac involvement and endomyocardial fibrosis, which have a poor prognosis. However, there is limited information regarding cardiac involvement among migrants from Latin America with eosinophilia related
Abiu Sempere   +16 more
doaj   +1 more source

Retrospective Study of Incidence and Prognostic Significance of Eosinophilia after Allogeneic Hematopoietic Stem Cell Transplantation: Influence of Corticosteroid Therapy

open access: yesTurkish Journal of Hematology, 2016
Objective: The clinical significance of eosinophilia after allogeneic hematopoietic stem cell transplantation is controversial. This study aimed to retrospectively study the impact of eosinophilia on the outcome of allogeneic hematopoietic stem cell ...
Wataru Yamamoto   +5 more
doaj   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger   +3 more
wiley   +1 more source

Knowledge and practice regarding eosinophilic gastrointestinal disorders other than eosinophilic esophagitis among pediatric gastroenterologists of the Latin American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

open access: yesJPGN Reports, EarlyView.
Abstract Objective Evaluating clinical practices in the management of non‐esophageal eosinophilic gastrointestinal disorders (non‐EoE EGIDs) among pediatric gastroenterologists in Latin America. Methods A cross‐sectional descriptive study was conducted using a survey distributed via the REDCap platform.
Sofia Paz   +17 more
wiley   +1 more source

Type II achalasia unmasked by EndoFLIP and high‐resolution manometry in a child with eosinophilic esophagitis

open access: yesJPGN Reports, EarlyView.
ABSTRACT Eosinophilic esophagitis (EoE) is a chronic immune‐mediated disease characterized by esophageal dysfunction and eosinophilic inflammation. Persistent dysphagia despite histologic remission should prompt evaluation for alternative etiologies. A 10‐year‐old male with asthma and eczema presented with progressive solid food dysphagia, daily non ...
Rasha Abi Radi Abou Jaoudeh   +2 more
wiley   +1 more source

Clinical phenotyping of asthma patients with elevated sputum eosinophils and low blood eosinophils: a post-hoc analysis of the multicentre ATLANTIS cohortResearch in context

open access: yesEBioMedicine
Summary: Background: Patients with eosinophilic asthma are responsive to treatment with corticosteroids and biologics. Eosinophilia is usually identified based on blood eosinophil counts, but there is discordance between blood and sputum in some cases ...
Pauline J.M. Kuks   +19 more
doaj   +1 more source

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