Results 111 to 120 of about 270,393 (395)

A case of eosinophilic gastroenteritis with eosinophilic ascites.

Nihon Naika Gakkai Zasshi, 1989
48才の女性が,水様性下痢便に続く著明な腹水で,近医より紹介された.末梢血白血球分画で好酸球が42%と著増を示し,また,腹水中の好酸球が84%を占めていた.開腹による小腸楔状切除生検にて,粘膜下層から漿膜下層にわたるほぼ全層に,好酸球の浸潤を認めた.これらから,本例はいわゆるMcNabbらの言うtransmural eosinophilic gastroenteritis with ascitesに相当すると思われる.
Mitsuya Harigane, Mamoru Nagao, Kunio Nagai, Akira Genda, Hiroyasu Ohara, Osamu Kawamura   +5 more
openaire   +4 more sources

The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer

Advanced Science, EarlyView.
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang, Bo Cheng, Chenyue Zhang, Chenglong Zhao, Ruiqing Wang, Xun Zhang, Dizhi Jiang, Xinyu Zhang, Xinyue Ma, Hongyuan Mao, Zerun Li, Chenhan Huang, Tianzi Wang, Kaiyue Guo, Liwen Wang, Ning Tang, Haiyong Wang   +16 more
wiley   +1 more source

A chondroblastic osteosarcoma of the coronoid process mimicking a fragmented coronoid process in a dog [PDF]

, 2016
A 6-year-old Rhodesian Ridgeback was presented with a 1.5 year history of right forelimb lameness. Clinical, radiological and computed tomographic findings suggested the presence of fragmented medial coronoid process.
Cirkel, Koen, De Rycke, Lieve, Gielen, Ingrid, Rasenberg, Wilhelmus Sebastianus Johannes, van Bree, Henri   +4 more
core   +1 more source

Choroid Plexus Fibroblast–ILC2 Niche Promotes Adult Hippocampal Neurogenesis after Traumatic Brain Injury

Advanced Science, EarlyView.
This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao, Xiaoming Guo, Sixuan Tian, Huaping Huang, Caidi Ying, Junjie Wang, Jiahao Zhang, Jun Lin, Anwen Shao, Jingyu Wang, Yuan Hong   +10 more
wiley   +1 more source

A detailed intake-status profiling of seafoods in adult food–protein–induced enterocolitis syndrome patients

Allergology International
Background: Adults with food-protein-induced enterocolitis syndrome (FPIES) often develop severe abdominal symptoms after eating seafood. However, no investigation of a food elimination strategy for adult FPIES patients has been performed to date ...
Sho Watanabe, Ayako Sato, Misugi Uga, Naoki Matsukawa, Rina Kusuda, Hiroko Suzuki, Saori Nagashima, Tsunehito Yauchi, Yukihiro Ohya, Ichiro Nomura   +9 more
doaj   +1 more source

Diagnosis and management of eosinophilic asthma: a US perspective. [PDF]

, 2014
Eosinophilic asthma is now recognized as an important subphenotype of asthma based on the pattern of inflammatory cellular infiltrate in the airway. Eosinophilic asthma can be associated with increased asthma severity, atopy, late-onset disease, and ...
Doherty, Taylor A, Walford, Hannah H
core   +1 more source

Adult‐onset eosinophilic airway diseases

Allergy. European Journal of Allergy and Clinical Immunology, 2020
Eosinophilic airway inflammation is one of the cardinal features of allergic airway diseases such as atopic asthma and allergic rhinitis. These childhood‐onset conditions are mediated by allergen and allergen‐specific IgE and often accompanied by other ...
K. Asano, S. Ueki, M. Tamari, Y. Imoto, S. Fujieda, M. Taniguchi   +5 more
semanticscholar   +1 more source

Coactosin‐Like Protein Reduces Prostaglandin D2 Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation

Advanced Science, EarlyView.
Coactosin‐like protein inhibits prostaglandin D₂ (PGD2) secretion by modulating alveolar macrophage polarization, thereby suppressing activation of the PGD2 receptor CRTH2 in Th2‐associated immune cells and alleviating allergic airway inflammation.
Li‐Long Pan, Zhengnan Ren, Binbin Li, Wenjie Liang, Yang Luo, Qin Yang, He Liu, Xiaoliang Dong, Haizhi Tian, Huimin Zou, Bengt Samuelsson, Olof Rådmark, Jia Sun   +12 more
wiley   +1 more source

Assessment of chronic rhinosinusitis with nasal polyps: Development of the Nasal Polyp Patient Assessment Scoring Sheet tool

Laryngoscope Investigative Otolaryngology
Background Chronic rhinosinusitis (CRS) is a heterogeneous disorder with a wide range of validated subjective and objective assessment tools to assess disease severity.
Saad Alsaleh, Nehal Kamal, Claire Hopkins, Hussain Al Rand, Osama A. Marglani, Abdulmohsen Alterki, Omar Abu Suliman, Talal Alandejani, Reda Kamel, Rashid Al Abri, Naif H. Alotaibi, Ahmad Al Amadi, Abdullah Bahakim, Joseph K. Han, Amin Javer, Ahmad R. Sedaghat, Philippe Gevaert   +16 more
doaj   +1 more source

PVC Nanoplastics Exposure Exacerbates Asthma through R‐Loop Accumulation and Subsequent STING Activation in Macrophages

Advanced Science, EarlyView.
Polyvinyl chloride (PVC) nanoplastics (NPs) are shown to aggravate allergic airway inflammation in asthma by triggering R‐loop accumulation and activating the cGAS‐STING pathway in macrophages. This study reveals a novel immunotoxic mechanism linking environmental plastic exposure to asthma pathogenesis and highlights potential molecular targets for ...
Qimei Bao, Yixing Huang, Mingcong Deng, Chunkai Zhang, Dan Zu, Hanyi He, Yangchan Hu, Yuke Zhong, Chen Liang, Haidong Liu, Wumin Dai, Yanhua He, Yaoshu Teng, Ji Jing, Yin Shi, Xiangdong Cheng, Zu Ye   +16 more
wiley   +1 more source