Results 121 to 130 of about 262,188 (421)

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Onset of Effect, Changes in Airflow Obstruction and Lung Volume, and Health-Related Quality of Life Improvements with Benralizumab for Patients with Severe Eosinophilic Asthma: Phase IIIb Randomized, Controlled Trial (SOLANA)

Journal of Asthma and Allergy, 2020
Reynold A Panettieri Jr,1 Tobias Welte,2 Kartik V Shenoy,3 Stephanie Korn,4 Margret Jandl,5 Edward M Kerwin,6 Rosa Feijoo,7 Peter Barker,8 Richard F Olsson,9 Ubaldo J Martin8 On behalf of the SOLANA Study Investigators1Pulmonary, Allergy and Critical ...
Panettieri RA Jr, Welte T, Shenoy KV, Korn S, Jandl M, Kerwin EM, Feijoo R, Barker P, Olsson RF, Martin UJ   +9 more
doaj  

A case of eosinophilic gastroenteritis with eosinophilic ascites.

Nihon Naika Gakkai Zasshi, 1989
48才の女性が,水様性下痢便に続く著明な腹水で,近医より紹介された.末梢血白血球分画で好酸球が42%と著増を示し,また,腹水中の好酸球が84%を占めていた.開腹による小腸楔状切除生検にて,粘膜下層から漿膜下層にわたるほぼ全層に,好酸球の浸潤を認めた.これらから,本例はいわゆるMcNabbらの言うtransmural eosinophilic gastroenteritis with ascitesに相当すると思われる.
Mitsuya Harigane, Mamoru Nagao, Kunio Nagai, Akira Genda, Hiroyasu Ohara, Osamu Kawamura   +5 more
openaire   +4 more sources

Granulomatous fasciitis followed by morphea profunda: Is granulomatous fasciitis part of a spectrum of deep morphea? A case report and review of the literature. [PDF]

, 2018
Although eosinophilic fasciitis is known to be part of the deep morphea spectrum, this first report of the coexistence of granulomatous fasciitis and morphea profunda suggests that granulomatous fasciitis may also be a part of the spectrum of deep ...
Christensen, Angie, Di Loreto, Christina, Guma, Monica, Jones, Karra A, Paravar, Taraneh, Smitaman, Edward   +5 more
core   +1 more source

Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment.

Gastroenterology, 2007
During the last decade, clinical practice saw a rapid increase of patients with esophageal eosinophilia who were thought to have gastroesophageal reflux disease (GERD) but who did not respond to medical and/or surgical GERD management. Subsequent studies
G. Furuta, C. Liacouras, M. Collins, S. Gupta, C. Justinich, P. Putnam, P. Bonis, E. Hassall, A. Straumann, M. Rothenberg   +9 more
semanticscholar   +1 more source

MiR‐221‐3p Attenuates IL‐33‐Induced Mast Cell Cytokine Expression by Targeting KIT

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Mast cells (MCs) are involved in type 2 inflammation in chronic rhinosinusitis with nasal polyps (CRSwNP), which depends on interleukin (IL)‐33 stimulation. MiR‐221 is reported to be an important regulator of MCs, and miR‐221‐3p can be expressed in CRSwNP. However, the role of miR‐221‐3p in CRSwNP is unclear. Methods Ethmoid tissues
Ruowu Liu, Jiao Zhou, Jing Zhou, Feng Liu, Yafeng Liu, Juan Meng, Luo Ba, Hengyi Xiao, Shixi Liu, Nan Zhang, Claus Bachert, Jintao Du   +11 more
wiley   +1 more source

Eosinophilic Esophagitis Is an Underlying Cause for Gastrointestinal Concerns in Children

Frontiers in Pediatrics, 2018
Eosinophilic esophagitis (EoE) is a chronic immune antigen-mediated disorder characterized by symptoms of esophageal dysfunction in combination with dense esophageal eosinophilia.
Kunsong Lee, Kunsong Lee, Glenn T. Furuta, Glenn T. Furuta, Nathalie Nguyen, Nathalie Nguyen   +5 more
doaj   +1 more source

Evidence-Based Guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis

Nature Reviews Rheumatology, 2023
G. Emmi, A. Bettiol, E. Gelain, I. Bajema, A. Berti, S. Burns, M. Cid, J. C. Cohen Tervaert, V. Cottin, E. Durante, Julia U. Holle, A. Mahr, M. D. Del Pero, C. Marvisi, J. Mills, S. Moiseev, F. Moosig, C. Mukhtyar, T. Neumann, I. Olivotto, C. Salvarani, B. Seeliger, R. Sinico, C. Taillé, B. Terrier, N. Venhoff, G. Bertsias, L. Guillevin, D. Jayne, A. Vaglio   +29 more
semanticscholar   +1 more source

Adult‐onset eosinophilic airway diseases

Allergy. European Journal of Allergy and Clinical Immunology, 2020
Eosinophilic airway inflammation is one of the cardinal features of allergic airway diseases such as atopic asthma and allergic rhinitis. These childhood‐onset conditions are mediated by allergen and allergen‐specific IgE and often accompanied by other ...
K. Asano, S. Ueki, M. Tamari, Y. Imoto, S. Fujieda, M. Taniguchi   +5 more
semanticscholar   +1 more source

A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED [PDF]

, 2016
RATIONALE AND OBJECTIVES: Asthma is a heterogeneous disease driven by diverse immunologic and inflammatory mechanisms. We used transcriptomic profiling of airway tissues to help define asthma phenotypes. METHODS: The transcriptome from bronchial biopsies
Adcock, IM, Auffray, C, Baribaud, F, Chanez, P, Chung, KF, Corfield, J, Dahlen, B, Dahlen, SE, De Meulder, B, Djukanovic, R, Fleming, L, Fowler, S, Guo, Y, Hoda, U, Howarth, P, Krug, N, Kuo, CS, Lefaudeux, D, Loza, M, Pandis, I, Pavlidis, S, Rossios, C, Rowe, A, Sandström, T, Shaw, D, Sousa, A, Sterk, PJ, U-BIOPRED Project Team, Wilson, SJ   +28 more
core   +4 more sources