Results 241 to 250 of about 270,393 (395)

Unveiling Benzoxazole‐Substituted Thiazolyl‐Pyrazole Derivatives Inducing Apoptosis by Targeting β‐Tubulin and Caspase‐3

open access: yesChemMedChem, EarlyView.
BP(1‐6) compounds designed from Benzoxazole and Thiazolyl‐Pyrazole scaffolds exhibited potent antitubulin and caspase‐3 activity in MDA‐MB‐231 cells. BP‐6 notably triggered apoptosis and disrupted cell proliferation. Docking studies validated strong binding affinities of BP‐2 and BP‐6 toward β‐tubulin and caspase‐3, suggesting promising therapeutic ...
Burak Kuzu   +3 more
wiley   +1 more source

Eosinophilic gastroenteritis with obstruction

open access: bronze, 1978
James H. Caldwell   +3 more
openalex   +1 more source

Think highly of immunoglobulin G4‐related chronic rhinosinusitis as a clinical entity in immunoglobulin G4‐related disease

open access: yesEye &ENT Research, EarlyView.
Abstract IgG4‐related chronic rhinosinusitis (IgG4‐related CRS) is gaining recognition among various specialized physicians. As a systemic disease involving multiple organs, IgG4‐related CRS is still not widely recognized as an independent clinical entity. Given the complexity of diagnosing autoimmune‐related multisystem diseases, early recognition and
Lianqi Wan   +3 more
wiley   +1 more source

Eosinophilic and Noneosinophilic Asthma

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2018
T. Carr, A. Zeki, M. Kraft
semanticscholar   +1 more source

EZH2 negatively regulates IL‐8 expression in human nasal epithelial cells through its histone methyltransferase activity

open access: yesEye &ENT Research, EarlyView.
Abstract Background Chronic rhinosinusitis (CRS), characterized by persistent inflammation of the nasal and sinus mucosa, exhibits an escalating global prevalence and incidence. Interleukin‐8 (IL‐8), a key chemokine driving neutrophil recruitment, is implicated in CRS pathogenesis.
Yu Song   +4 more
wiley   +1 more source

Targeting thymic stromal lymphopoietin in nasal type 2 inflammation

open access: yesEye &ENT Research, EarlyView.
Abstract Epithelial cell‐derived thymic stromal lymphopoietin (TSLP) plays a crucial role in mediating type 2 immune responses, which is one of the key underlying pathophysiological mechanisms of allergic rhinitis (AR) and most presentations of chronic rhinosinusitis with nasal polyps (CRSwNP).
Xintong Li   +3 more
wiley   +1 more source

Autopsy findings in cases of fatal COVID‐19 vaccine‐induced myocarditis

open access: yesESC Heart Failure, EarlyView.
Abstract COVID‐19 vaccines have been linked to myocarditis, which, in some circumstances, can be fatal. This systematic review aims to investigate potential causal links between COVID‐19 vaccines and death from myocarditis using post‐mortem analysis.
Nicolas Hulscher   +3 more
wiley   +1 more source

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