Esophageal virtual disease landscape using mechanics-informed machine learning [PDF]
Artificial Intelligence in Medicine. 134 (2022) 102435, 2021 The pathogenesis of esophageal disorders is related to the esophageal wall mechanics. Therefore, to understand the underlying fundamental mechanisms behind various esophageal disorders, it is crucial to map the esophageal wall mechanics-based parameters onto physiological and pathophysiological conditions corresponding to altered bolus transit and ...
arxiv +1 more source
Natural language processing to automatically extract the presence and severity of esophagitis in notes of patients undergoing radiotherapy [PDF]
, 2023 Radiotherapy (RT) toxicities can impair survival and quality-of-life, yet remain under-studied. Real-world evidence holds potential to improve our understanding of toxicities, but toxicity information is often only in clinical notes. We developed natural language processing (NLP) models to identify the presence and severity of esophagitis from notes of
arxiv +1 more source
Mechanics Informed Fluoroscopy of Esophageal Transport [PDF]
Biomechanics and Modeling in Mechanobiology. 20 (2021) 925-940, 2020 Fluoroscopy is a radiographic procedure for evaluating esophageal disorders such as achalasia, dysphasia and gastroesophageal reflux disease (GERD). It performs dynamic imaging of the swallowing process and provides anatomical detail and a qualitative idea of how well swallowed fluid is transported through the esophagus.
arxiv +1 more source
Harnessing Artificial Intelligence to Infer Novel Spatial Biomarkers for the Diagnosis of Eosinophilic Esophagitis [PDF]
arXiv, 2022 Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory condition of the esophagus associated with elevated esophageal eosinophils. Second only to gastroesophageal reflux disease, EoE is one of the leading causes of chronic refractory dysphagia in adults and children. EoE diagnosis requires enumerating the density of esophageal eosinophils in
arxiv
Machine learning approach for biopsy-based identification of eosinophilic esophagitis reveals importance of global features [PDF]
arXiv, 2021 Goal: Eosinophilic esophagitis (EoE) is an allergic inflammatory condition characterized by eosinophil accumulation in the esophageal mucosa. EoE diagnosis includes a manual assessment of eosinophil levels in mucosal biopsies - a time-consuming, laborious task that is difficult to standardize. One of the main challenges in automating this process, like
arxiv
Upper Esophageal Sphincter Opening Segmentation with Convolutional Recurrent Neural Networks in High Resolution Cervical Auscultation [PDF]
IEEE Journal of Biomedical and Health Informatics (2020), 2020 Upper esophageal sphincter is an important anatomical landmark of the swallowing process commonly observed through the kinematic analysis of radiographic examinations that are vulnerable to subjectivity and clinical feasibility issues. Acting as the doorway of esophagus, upper esophageal sphincter allows the transition of ingested materials from ...
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Deep Learning-Based Open Source Toolkit for Eosinophil Detection in Pediatric Eosinophilic Esophagitis [PDF]
arXiv, 2023 Eosinophilic Esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease, characterized by symptoms related to esophageal dysfunction and histological evidence of eosinophil-dominant inflammation. Owing to the intricate microscopic representation of EoE in imaging, current methodologies which depend on manual identification are not only ...
arxiv
Advancing Eosinophilic Esophagitis Diagnosis and Phenotype Assessment with Deep Learning Computer Vision [PDF]
arXiv, 2021 Eosinophilic Esophagitis (EoE) is an inflammatory esophageal disease which is increasing in prevalence. The diagnostic gold-standard involves manual review of a patient's biopsy tissue sample by a clinical pathologist for the presence of 15 or greater eosinophils within a single high-power field (400x magnification).
arxiv
PECNet: A Deep Multi-Label Segmentation Network for Eosinophilic Esophagitis Biopsy Diagnostics [PDF]
arXiv, 2021 Background. Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus associated with elevated numbers of eosinophils. Disease diagnosis and monitoring requires determining the concentration of eosinophils in esophageal biopsies, a time-consuming, tedious and somewhat subjective task currently performed by pathologists ...
arxiv
Harnessing Digital Pathology And Causal Learning To Improve Eosinophilic Esophagitis Dietary Treatment Assignment [PDF]
arXiv, 2023 Eosinophilic esophagitis (EoE) is a chronic, food antigen-driven, allergic inflammatory condition of the esophagus associated with elevated esophageal eosinophils. EoE is a top cause of chronic dysphagia after GERD. Diagnosis of EoE relies on counting eosinophils in histological slides, a manual and time-consuming task that limits the ability to ...
arxiv