Results 131 to 140 of about 110,204 (324)

Endoscopic Features of Eosinophilic Esophagitis: From Its Origins to Current Practice and Innovations. Literature Review and Personal Experience

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to systematize literature data and the authors’ own findings regarding the endoscopic features of eosinophilic esophagitis.Key points. Eosinophilic esophagitis is a chronic inflammatory disease of the esophagus characterized by marked eosinophilic ...
E. D. Fedorov, V. O. Kaibysheva, E. V. Gorbachev, A. I. Mokritskiy, L. M. Mikhaleva, K. S. Maslyonkina, S. G. Shapovalianc   +6 more
doaj   +1 more source

Esofagite eosinofílica: uma patologia emergente em pediatría.

Acta Médica Portuguesa, 2009
Eosinophilic Esophagitis has been increasingly diagnosed and results from a chronic esophagic inflammation with eosinophilic infiltrate.Evaluation of the diagnosed paediatric cases in our centre between 2004 and 2008 and revision of current literature on
Hugo Braga-Tavares, Andreia Teles, Rosete Nogueira, Fernando Cardoso Rodrigues, Cristina Costa   +4 more
doaj   +1 more source

Specific MicroRNA Pattern in Colon Tissue of Young Children with Eosinophilic Colitis [PDF]

, 2017
Eosinophilic colitis (EC) is a common cause of haematochezia in infants and young children. The exact pathomechanism is not understood, and the diagnosis is challenging. The role of microRNAs as key class of regulators of mRNA expression and translation
András Arató, Attila Szabó, Bala, Bálint Tél, Erna Sziksz, Gábor Veres, Katalin Borka, Li, Nóra Béres, Zoltán Kiss   +9 more
core   +2 more sources

Esophageal Microbiome in Eosinophilic Esophagitis

PLOS ONE, 2015
The microbiome has been implicated in the pathogenesis of a number of allergic and inflammatory diseases. The mucosa affected by eosinophilic esophagitis (EoE) is composed of a stratified squamous epithelia and contains intraepithelial eosinophils.
Harris, J. Kirk, Fang, R., Wagner, Brandie D., Choe, Ha Na, Kelly, Caleb J., Schroeder, Shauna, Moore, Wendy, Stevens, Mark J., Yeckes, Alyson, Amsden, Katie, Kagalwalla, Amir F., Zalewski, Angelika, Hirano, Ikuo, Gonsalves, Nirmala, Henry, Lauren N., Masterson, Joanne C., Robertson, Charles E., Leung, Donald Y., Pace, Norman R., Ackerman, Steven J., Furuta, Glenn T., Fillon, Sophie A.   +21 more
openaire   +5 more sources

Therapeutic advances in pruritus as a model of personalized medicine

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Recent advances in itch biology reveal that chronic pruritus arises from distinct neuroimmune pathways driven by cytokines, JAK, BTK and GPCRs. Targeted biologics and small molecule inhibitors such as dupilumab, nemolizumab, remibrutinib and JAK inhibitors precisely modulate these pathways, leading to a new era of personalized therapeutics in pruritus.
Kelsey Auyeung, Ramsey Kubofcik, Brian S. Kim   +2 more
wiley   +1 more source

The Milan Score Predicts Objective Gastroesophageal Reflux Disease in Patients With Type 2 Esophagogastric Junction

Neurogastroenterology &Motility, EarlyView.
The novel manometric parameter Milan Score could be useful in predicting which patients with type 2 EGJ have a high likelihood of objective GERD, therefore discriminating which patients may need escalation of GERD investigation and management. ABSTRACT Introduction High‐resolution manometry (HRM) allows assessment of esophagogastric junction (EGJ ...
Davide Ferrari, Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Ivan Kristo, Salvatore Tolone, Elisa Marabotto, Daniele Bernardi, Sebastian F. Schoppmann, Benjamin D. Rogers, Anthony Hobson, Jordan Haworth, Yeong Yeh Lee, Brian E. Louie, Takahiro Masuda, Megan L. Ivy, Pamela Milito, Erica Centorrino, Dimitrios Theodorou, Tania Triantafyllou, Andrea Pasta, Francesco Calabrese, Vincent Tee, Lorenzo Cusmai, Roberto Penagini, Marina Coletta, Edoardo Savarino, Emanuele Asti, C. Prakash Gyawali, Nicola De Bortoli   +29 more
wiley   +1 more source

Granulomatous hyperinflammatory state induced by dupilumab treatment for eosinophilic esophagitis

Journal of Allergy and Clinical Immunology: Global
We present the first case of a dupilumab-induced hyperinflammatory state in the setting of underlying eosinophilic esophagitis characterized by multisystem granulomatous inflammation.
Kanak V. Kennedy, MD, Anna Costello, MD, Melissa A. Lerman, MD, PhD, Jon M. Burnham, MD, Aoife Corcoran, MD, Joseph Piccione, DO, Alexandra Grier, MD, PhD, Kathleen Sullivan, MD, PhD, Terri Whitehorn-Brown, MD, Caitlin J. Alexander, MD, Laura S. Finn, MD, Benjamin J. Wilkins, MD, PhD, Amanda B. Muir, MD   +12 more
doaj   +1 more source

The case of the infection that wasn′t !

Journal of Global Infectious Diseases, 2009
Eosinophilic esophagitis is an under-recognized inflammatory disorder of the esophagus. It has been frequently diagnosed in pediatric patients; however, over the last few years, there has been an increase in the number of cases recognized in adults as ...
Jennifer Eatrides, Veronica T Tucci, Richard Schrot   +2 more
doaj   +1 more source

Prostaglandin D2 receptor d ‐type prostanoid receptor 2 mediates eosinophil trafficking into the esophagus [PDF]

, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108045/1/dote12118 ...
Wu, X., Yu, S., Zhang, S.
core   +1 more source

The Milan Score is an Effective Manometric Tool to Predict Gastroesophageal Reflux in Patients With Laryngopharyngeal Symptoms

Neurogastroenterology &Motility, EarlyView.
Patients with isolated LPS demonstrated a lower likelihood of EGJ disruption, pathologic GERD, and abnormal Milan score. The Milan score performed similarly well in the identification of GERD in both LPS and typical symptoms. The Milan score could therefore be used as an upfront test in LPS patients.
Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Ivan Kristo, Nicola De Bortoli, Salvatore Tolone, Elisa Marabotto, Daniele Bernardi, Sebastian F. Schoppmann, Roberto Penagini, Benjamin Rogers, Anthony Hobson, Jordan Haworth, Brian Louie, Yeong Yeh Lee, Vincent Tee, Takahiro Masuda, Dimitrios Theodorou, Tania Triantafyllou, Benedetta Barcella, Lorenzo Cusmai, Michele Puricelli, Marina Coletta, Vito Annese, Edoardo Vincenzo Savarino, Emanuele Luigi Giuseppe Asti, C. Prakash Gyawali   +26 more
wiley   +1 more source