Results 121 to 130 of about 18,778 (231)
Dupilumab, a fully human monoclonal antibody that blocks key drivers of type 2 inflammation, is approved across 8 diseases, including eosinophilic esophagitis. Subcutaneous dupilumab 300 mg weekly improved outcomes vs. placebo in adults (aged ≥ 18 years) and adolescents (aged ≥ 12 to < 18 years) during the phase III LIBERTY EoE TREET study (NCT03633617)
Jenny‐Hoa Nguyen +8 more
wiley +1 more source
A unique association between herpes simplex esophagitis and eosinophilic esophagitis: a case report [PDF]
Herpes simplex esophagitis (HSE) is a viral infection of the esophagus caused by the herpes simplex virus (HSV), most commonly HSV-1. It predominantly presents among immunosuppressed individuals. Eosinophilic esophagitis (EoE) is a chronic, inflammatory,
Sahil Sabharwal +4 more
doaj +1 more source
ABSTRACT The Rare Diseases Clinical Research Network (RDCRN) was established to improve diagnosis, treatment, and research collaboration across rare diseases through collaborative, multi‐site, translational, and clinical research. Its governance framework promotes efficient data sharing and collaboration among research consortia, NIH representatives ...
Mirna Chehade +9 more
wiley +1 more source
Eosinophilic esophagitis and anaphylaxis due to cow's milk in an infant
Food allergies are often seen in infancy and usually show the clinical signs in the form of type I hypersensitivity reaction. However, a combination of food allergies can sometimes be found in the same patient.
Erdem Topal +6 more
doaj
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan +14 more
wiley +1 more source
Algorithms of Patient Selection for Allergen Immunotherapy
Allergy, EarlyView.
U. Petra Zieglmayer +5 more
wiley +1 more source
How to Reduce Wheat Allergens and FODMAPs in Foods: A Critical Review of Patents
ABSTRACT Background and Objectives Supported by scientific evidence, this critical review of the patent literature examined methods to reduce wheat allergens and FODMAPs in foods, which may trigger digestive disorders and other health problems. The following topics were covered: proteolytic enzymes, proteolytic bacteria and yeasts, separation, plant ...
Pierre Gélinas, Jérémie Théolier
wiley +1 more source
The Skinny on Eosinophilic Esophagitis
Eosinophilic esophagitis--a disease that even most physicians know little about--is becoming increasingly common. Often starting in childhood with eating difficulties and symptoms of gastroesophageal reflux disease, it progresses with increasing inflammation, fibrosis, and strictures until the esophagus is visibly narrowed on radiography.
openaire +3 more sources
ABSTRACT Eosinophilic esophagitis (EoE) is a chronic, immune‐mediated disease requiring long‐term therapy. Dupilumab, an interleukin‐4 and interleukin‐13 receptor antagonist, is approved for EoE at a weekly 300 mg dosing regimen. However, data on reduced‐frequency dosing, especially in pediatric patients, remain limited.
Giovanni Scatigna +4 more
wiley +1 more source

