Results 101 to 110 of about 44,426 (222)

Eosinophilic esophagitis: an Italian experience

, 2010
Background: eosinophilic esophagitis is an esophageal disorder characterized by esophageal and/or upper gastrointestinal tract symptoms, and by dense esophageal eosinophilia associated with a normal gastric and duodenal mucosa.
Corazzi,N., Tosi,P., Vindigni,C., Frosini,G., Villanacci,V., Pedruzzi,E., Rocca,B. J., Bassotti,G., Marini,M.   +8 more
core   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Mechanisms underpinning the progression of nondysplastic Barrett's oesophagus to cancer

The FEBS Journal, EarlyView.
Barrett's oesophagus confers a low but significant cancer risk. The condition is common but we do not have effective biomarkers to identify susceptible patients. We believe that there is no single factor that determines cancer risk and an understanding of the combinations of interactions (via gene expression and natural selection) between the Barrett's
Yannick H. Derwa, Meng‐Lay Lin, Stuart A. C. McDonald   +2 more
wiley   +1 more source

Esofagite eosinofílica: uma patologia emergente em pediatría.

Acta Médica Portuguesa, 2009
Eosinophilic Esophagitis has been increasingly diagnosed and results from a chronic esophagic inflammation with eosinophilic infiltrate.Evaluation of the diagnosed paediatric cases in our centre between 2004 and 2008 and revision of current literature on
Hugo Braga-Tavares, Andreia Teles, Rosete Nogueira, Fernando Cardoso Rodrigues, Cristina Costa   +4 more
doaj   +1 more source

Esophageal Microbiome in Eosinophilic Esophagitis

PLOS ONE, 2015
The microbiome has been implicated in the pathogenesis of a number of allergic and inflammatory diseases. The mucosa affected by eosinophilic esophagitis (EoE) is composed of a stratified squamous epithelia and contains intraepithelial eosinophils.
Harris, J. Kirk, Fang, R., Wagner, Brandie D., Choe, Ha Na, Kelly, Caleb J., Schroeder, Shauna, Moore, Wendy, Stevens, Mark J., Yeckes, Alyson, Amsden, Katie, Kagalwalla, Amir F., Zalewski, Angelika, Hirano, Ikuo, Gonsalves, Nirmala, Henry, Lauren N., Masterson, Joanne C., Robertson, Charles E., Leung, Donald Y., Pace, Norman R., Ackerman, Steven J., Furuta, Glenn T., Fillon, Sophie A.   +21 more
openaire   +5 more sources

Growth Assessment in Children Under 12 Years With Moderate‐to‐Severe Atopic Dermatitis Included in the PEDISTAD Observational Registry

Pediatric Dermatology, EarlyView.
ABSTRACT Background/Objective The multifactorial disease burden of moderate‐to‐severe atopic dermatitis (AD) may affect children's growth. We report height, weight, and body mass index (BMI) of children under 12 years old with moderate‐to‐severe AD in comparison to the general population.
Amy S. Paller, Alan D. Irvine, Eulalia Baselga, Marlies de Graaf, Elaine C. Siegfried, Michael J. Cork, Michele Ramien, Lawrence F. Eichenfield, Bryan Adams, Rajan Gupta, Marius Ardeleanu, Annie Zhang   +11 more
wiley   +1 more source

Eosinophilic esophagitis: literature review and original case presentation

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
The aim of publication. To show features of clinical pattern, difficulties of diagnostics and treatment of eosinophilic esophagitis at the example of clinical case.Features of clinical case.
V. T. Ivashkin, Ye. K. Baranskaya, V. O. Kaybysheva, Ye. V. Ivanova, Ye. D. Fedorov   +4 more
doaj  

Granulomatous hyperinflammatory state induced by dupilumab treatment for eosinophilic esophagitis

Journal of Allergy and Clinical Immunology: Global
We present the first case of a dupilumab-induced hyperinflammatory state in the setting of underlying eosinophilic esophagitis characterized by multisystem granulomatous inflammation.
Kanak V. Kennedy, MD, Anna Costello, MD, Melissa A. Lerman, MD, PhD, Jon M. Burnham, MD, Aoife Corcoran, MD, Joseph Piccione, DO, Alexandra Grier, MD, PhD, Kathleen Sullivan, MD, PhD, Terri Whitehorn-Brown, MD, Caitlin J. Alexander, MD, Laura S. Finn, MD, Benjamin J. Wilkins, MD, PhD, Amanda B. Muir, MD   +12 more
doaj   +1 more source

TNFSF14/LIGHT responses in intestinal and oesophageal fibroblasts are differentially modulated by hydroxylase inhibitors

The Journal of Physiology, EarlyView.
Abstract figure legend LIGHT is a mutual mediator of intestinal and oesophageal fibroblast inflammation with common as well as tissue‐specific effects. Hydroxylase inhibitors can selectively suppress inflammatory factors in both cell types, albeit targeting different signalling pathways.
Cian M. Ohlendieck, Carlos Matellan, Cristina Bauset, Bella Raphael, Mary Nwaezeigwe, Emer Flynn, Kevin Okamoto, Desmond Winter, Colm Collins, Katie Doogan, Seán T. Martin, Glen Doherty, Seema S. Aceves, Mario C. Manresa   +13 more
wiley   +1 more source

An enigma of eosinophilic esophagitis [PDF]

, 2017
Introduction. Eosinophilic esophagitis is a chronic immunogenic-antigen mediated disease of the esophagus, characterized by symptoms related to esophagus dysfunction, histologically defined by over 15 eosinophil counts seen in high-power microscopic ...
Damjanov Dragomir, Živojinov Mirjana, Krnetić Žarko, Savić Željka, Vračarić Vladimir, Jocić Tatiana   +5 more
core   +1 more source