Results 91 to 100 of about 12,780 (219)

Esophageal motility in eosinophilic esophagitis

Revista de Gastroenterología de México (English Edition), 2015
Eosinophilic esophagitis (EoE) is characterized by eosinophilic infiltration of the esophagus and is a potential cause of dysphagia and food impaction, most commonly affecting young men. Esophageal manometry findings vary from normal motility to aperistalsis, simultaneous contractions, diffuse esophageal spasm, nutcracker esophagus or hypotonic lower ...
A.H. Weiss, N. Iorio, R. Schey
openaire   +3 more sources

Differential Roles for IL‐4Rα and IL‐13Rα1 in Immune Cell Infiltration and Epithelial Remodeling in Experimental Eosinophilic Gastritis

Allergy, EarlyView.
This study described the development of an experimental model for eosinophilic gastritis (EoG). Experimental EoG recapitulates histopathological features of human disease. including foveolar elongation, fibrosis, eosinophilia, mastocytosis and shared transcriptional programs.
Anish Dsilva, Shraddha Sharma, Shireen Barakey, Ariel Wagner, Alice Keisar, Tali Bar‐on, Michal Itan, Ariel Munitz   +7 more
wiley   +1 more source

Pharmacologic Treatment of Eosinophilic Esophagitis: An Update

, 2018
Eosinophilic esophagitis (EoE) is defined as a chronic, immune-medicated or antigen-mediated, esophageal disease, characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominant inflammation.
Safroneeva, Ekaterina, Alex Straumann, Straumann, Alex, Safroneeva, E., Alain M. Schoepfer, Ekaterina Safroneeva, Straumann, A., Schoepfer, Alain M, Schoepfer, A.M.   +8 more
core   +1 more source

Eosinophilic Oesophagitis Beyond the Oesophagus: High Prevalence of Chronic Rhinosinusitis‐Type Symptoms and Their Impact on Symptom Severity in Swiss EoE Cohort Study Patients

Alimentary Pharmacology &Therapeutics, EarlyView.
Among 211 prospectively followed Swiss patients with eosinophilic oesophagitis, chronic rhinosinusitis was two‐ to three‐fold more common than in the general population. It was associated with greater oesophageal symptom severity and, in a quarter of cases, was experienced by patients as more debilitating than the underlying oesophageal disease ...
Gebhardt Aidan, Kreienbühl Andrea, Greuter Thomas, Schlag Christoph, Nennstiel Simon, Saner Catherine, Rossel Jean‐Benoit, Mauthe Tina, M. Meerwein Christian, Schoepfer Alain, B. Soyka Michael, Straumann Alex, Biedermann Luc, on behalf of the Swiss EoE Cohort Study Group, Patrick Aepli, Luc Biedermann, Ruggero Biral, Carine Blanchard, Simon Buetikofer, Emanuel Burri, Joachim Diebold, Carolien Dietrich, Annett Franke, Michèle Gwerder, Thomas Greuter, Chantal Hasler, Wolfram Jochum, Tanay Kaymak, Andrea Kreienbühl, Katline Metzger‐Peter, Fritz Murray, Simon Nennstiel, Peter Netzer, Jan Hendrik Niess, Gabrielle Reichhart, Cristiana Quattropani, Elodie Ristorcelli, Jean‐Benoit Rossel, Ekaterina Safroneeva, Catherine Saner, Alain Schoepfer, Philip Schreiner, Christine Sempoux, Dagmar Simon, Hans‐Uwe Simon, Alex Straumann, Sven Trelle, Achim Weber, Niels Willi, Elina Wuethrich, Marcel Zwahlen, Michael Scharl, Marcin Wawrzyniak   +52 more
wiley   +1 more source

The case of the infection that wasn′t !

Journal of Global Infectious Diseases, 2009
Eosinophilic esophagitis is an under-recognized inflammatory disorder of the esophagus. It has been frequently diagnosed in pediatric patients; however, over the last few years, there has been an increase in the number of cases recognized in adults as ...
Jennifer Eatrides, Veronica T Tucci, Richard Schrot   +2 more
doaj   +1 more source

Functional and Phenotypic Studies of Eosinophilic Granulocytes in Patients with Eosinophilic Esophagitis

, 2015
Eosinophilic Esophagitis (EoE) is a chronic inflammatory disorder of unknown etiology, in which the esophagus is infiltrated by eosinophils and T cells. Topical corticosteroids are one of the treatment options for patients with EoE.
Lingblom, Christine
core   +1 more source

Granulomatous hyperinflammatory state induced by dupilumab treatment for eosinophilic esophagitis

Journal of Allergy and Clinical Immunology: Global
We present the first case of a dupilumab-induced hyperinflammatory state in the setting of underlying eosinophilic esophagitis characterized by multisystem granulomatous inflammation.
Kanak V. Kennedy, MD, Anna Costello, MD, Melissa A. Lerman, MD, PhD, Jon M. Burnham, MD, Aoife Corcoran, MD, Joseph Piccione, DO, Alexandra Grier, MD, PhD, Kathleen Sullivan, MD, PhD, Terri Whitehorn-Brown, MD, Caitlin J. Alexander, MD, Laura S. Finn, MD, Benjamin J. Wilkins, MD, PhD, Amanda B. Muir, MD   +12 more
doaj   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Association between Eosinophilic Esophagitis and Food Protein-Induced Enterocolitis Syndrome in Children

, 2018
Background: The prevalence of food allergy in the pediatric population is increasing. Classic IgE-mediated allergies have been well studied. However, less is known about non-IgE-mediated allergies.
Gerken, Ashley
core   +1 more source

Eosinophilic esophagitis: literature review and original case presentation

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
The aim of publication. To show features of clinical pattern, difficulties of diagnostics and treatment of eosinophilic esophagitis at the example of clinical case.Features of clinical case.
V. T. Ivashkin, Ye. K. Baranskaya, V. O. Kaybysheva, Ye. V. Ivanova, Ye. D. Fedorov   +4 more
doaj