Results 21 to 30 of about 110,204 (324)

Mechanistic Insights into Eosinophilic Esophagitis: Therapies Targeting Pathophysiological Mechanisms

open access: yesCells, 2023
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease characterized by eosinophilic infiltration of the esophagus. It arises from a complex interplay of genetic predisposition (susceptibility loci), environmental triggers (allergens and ...
Sara Massironi   +6 more
semanticscholar   +1 more source

Eosinophilic esophagitis [PDF]

open access: yesCurrent Opinion in Pediatrics, 2005
Previously perceived as an anomaly, eosinophilic esophagitis is now frequently diagnosed by both pediatric and adult specialists including gastroenterologists, allergists, pathologists, and otolaryngologists. Research efforts initially focused on characterization of the clinical, endoscopic, and histologic features of this disorder. In the last 3 years,
Richard J, Noel, Marc E, Rothenberg
openaire   +4 more sources

The eosinophilic esophagitis and IgG4-related disease involving the esophagus [PDF]

open access: yesТерапевтический архив, 2020
The study of eosinophilic esophagitis has become a dynamic field with an evolving understanding of the pathogenesis, diagnosis, and treatment. Immunoglobulin G4 (IgG4)-related disease exhibits systemic involvement but very rarely involves the esophagus ...
N. V. Bakulina   +5 more
doaj   +1 more source

Medical treatment of eosinophilic esophagitis

open access: yesCochrane Database of Systematic Reviews, 2023
Background Eosinophilic esophagitis (EoE) is a chronic antigen‐mediated eosinophilic inflammatory disease isolated to the esophagus. As a clinicopathologic disorder, a diagnosis of EoE requires a constellation of clinical symptoms of esophageal ...
J. Franciosi   +11 more
semanticscholar   +1 more source

Personalized and Precision Medicine in Asthma and Eosinophilic Esophagitis: The Role of T2 Target Therapy

open access: yesPharmaceutics, 2023
The role of type 2 inflammation has been progressively associated with many diseases, including severe asthma, atopic dermatitis, nasal polyposis, eosinophilic granulomatosis with polyangiitis, and, recently, eosinophilic esophagitis.
Diego Bagnasco   +7 more
doaj   +1 more source

Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis.

open access: yesNew England Journal of Medicine, 2022
BACKGROUND Dupilumab, a fully human monoclonal antibody, blocks interleukin-4 and interleukin-13 signaling, which have key roles in eosinophilic esophagitis.
E. Dellon   +29 more
semanticscholar   +1 more source

A Case of Eosinophilic Esophagitis Associated with Herpes Esophagitis in a Pediatric Patient [PDF]

open access: yesClinical Endoscopy, 2019
Eosinophilic esophagitis is a rare disease in Asian countries, but its incidence is growing rapidly in Western countries. The main pathophysiology of eosinophilic esophagitis is esophageal epithelial barrier dysfunction; disruption of the esophageal ...
Jisun Kim, Kunsong Lee, Wonae Lee
doaj   +1 more source

Type 2 Inflammation in Eosinophilic Esophagitis: From Pathophysiology to Therapeutic Targets

open access: yesFrontiers in Physiology, 2022
Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease of the esophagus characterized clinically by symptoms related to esophageal dysfunction and histologically by eosinophil-predominant inflammation, whose incidence is rising.
F. Racca   +11 more
semanticscholar   +1 more source

Concentrations of Cysteinyl Leukotrienes in Various Biological Fluids of Children with Bronchial Asthma, Atopic Dermatitis and Food Protein Induced Enterocolitis [PDF]

open access: yes, 2019
Clinical manifestation of food allergy is characterized by polymorphic cutaneous, respiratory and gastrointestinal syndromes. Leukotrienes occupy a key place in the pathogenesis of a wide range of inflammatory diseases, including bronchial asthma ...
Haiduchyk, H. (Halyna)   +1 more
core   +4 more sources

Eosinophilic Esophagitis in Children: Clinical Cases

open access: yesКубанский научный медицинский вестник, 2022
Background. Eosinophilic esophagitis (Ee) is a chronic immune-mediated disease of the esophagus, which is characterized by symptoms of esophageal dysfunction and marked eosinophilic infiltration of the mucous membrane (MM) of the organ.
A. V. Burlutskaya   +5 more
doaj   +1 more source

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