Results 181 to 190 of about 1,585,745 (267)

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, Volume 13, Issue 56, 9 October 2026.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Advances and ongoing challenges in eosinophilic gastrointestinal disorders presented at the CEGIR/TIGERs Symposium at the 2024 American Academy of Allergy, Asthma & Immunology meeting. [PDF]

J Allergy Clin Immunol
Wright BL, Abonia JP, Abud EM, Aceves SS, Ackerman SJ, Braskett M, Chang JW, Chehade M, Constantine GM, Davis CM, Dellon ES, Doyle AD, Durban R, Hill DA, Jensen ET, Kewalramani A, Khoury P, Klion AD, Kottyan L, Kuang FL, McGowan EC, Ruffner MA, Spencer LA, Spergel JM, Uchida AM, Wechsler JB, Pesek RD.   +26 more
europepmc   +1 more source

Clinical and Psychological Impact of COVID-19 Infection in Adult Patients with Eosinophilic Gastrointestinal Disorders during the SARS-CoV-2 Outbreak. [PDF]

J Clin Med, 2020
Savarino EV, Iovino P, Santonicola A, Ghisa M, Laserra G, Barberio B, Maniero D, Lorenzon G, Ciacci C, Savarino V, Zingone F.   +10 more
europepmc   +1 more source

Ensemble‐Based Machine Learning Models for Classifying Intervention‐Related Psychological Outcome Patterns in Menopausal Women Treated With Pimpinella anisum

Brain and Behavior, Volume 16, Issue 10, October 2026.
This study develops an ensemble‐based machine learning approach to detect and predict psychological disorders in menopausal women using clinical and questionnaire data. Random Forest achieved the best performance. The framework supports early risk identification and integrates statistical validation with Unani‐based and home remedy interventions to ...
Md Belal Bin Heyat, Arshiya Sultana, Attiq Ur Rehman, Arfa Begum, Mohamad Sawan   +4 more
wiley   +1 more source

Increased Lymphocyte Proportions as a Candidate Biomarker for Immune‐Related Adverse Events in Patients Treated With Immune Checkpoint Inhibitors and Chemotherapy

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Combination therapy comprising immune checkpoint inhibitors (ICIs) and chemotherapy is standard treatment for many cancer types. However, the management of adverse events (AEs) induced by combination therapy is more complicated than that of AEs induced by ICI monotherapy.
Nanami Ito, Yoshihiko Tasaki, Yosuke Sugiyama, Takehiro Uemura, Keisuke Yokota, Ryo Ogawa, Takaya Shimura, Daisuke Kawakita, Yumi Wanifuchi‐Endo, Yoshihisa Mimura, Moeko Iida, Kunihiro Odagiri, Yuka Kimura, Misato Tomita, Yuji Hotta, Tatsuya Toyama, Shinichi Iwasaki, Hiromi Kataoka, Shuji Takiguchi, Katsuhiro Okuda, Akio Niimi, Yoko Furukawa‐Hibi   +21 more
wiley   +1 more source

Association Between Endoscopic and Histologic Findings in a Multicenter Retrospective Cohort of Patients with Non-esophageal Eosinophilic Gastrointestinal Disorders. [PDF]

Dig Dis Sci, 2020
Pesek RD, Reed CC, Collins MH, Muir AB, Fulkerson PC, Menard-Katcher C, Falk GW, Kuhl J, Magier AZ, Ahmed FN, Demarshall M, Gupta A, Gross J, Ashorobi T, Carpenter CL, Krischer JP, Gonsalves N, Hirano I, Spergel JM, Gupta SK, Furuta GT, Rothenberg ME, Dellon ES, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR).   +23 more
europepmc   +1 more source

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
Dunia Hatabah, Martha E. Stewart, Nathan Maassel, James P. Stevens, Claudia R. Morris, Chris A. Rees   +5 more
wiley   +1 more source

Bioactive Compounds and Antidiabetic Properties of Launaea mucronata Hydroethanolic Extract: Phytochemical and Pharmacological Insights

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Phytochemical and biological profiling of Launaea mucronata aerial parts reveals six bioactive constituents alongside potent antioxidant and antidiabetic properties. The hydroethanolic extract inhibits key carbohydrate‐metabolizing enzymes and exerts marked hypoglycemic and insulinotropic effects with histological restoration of metabolic organs in ...
Amira Mohamed, Dalia El Amir, Maha M. Abdel‐Fattah, Mohamed A. Zaki, Rabab Mohammed, Marwa H. A. Hassan   +5 more
wiley   +1 more source

Joint ESPGHAN/NASPGHAN Guidelines on Childhood Eosinophilic Gastrointestinal Disorders Beyond Eosinophilic Esophagitis

Introduction: Eosinophilic gastrointestinal disorders beyond eosinophilic esophagitis (non-EoE EGIDs) are rare chronic inflammatory disorders of the gastrointestinal (GI) tract.
Ohtsuka, Yoshikazu, Menard-Katcher, Calies, Oliva, Salvatore, Papadopoulou, Alexandra, Vieira, Mario C., Rothenberg, Marc E., Orel, Rok, Strauman, Alex, Carneiro, Fatima, Amil-Dias, Jorge, Gonsalves, Nirmala, Koletzko, Sibylle, Furuta, Glenn T., Zevit, Noam, Liacouras, Chris, Collins, Margaret H., Gupta, Sandeep K., Bredenoord, Albert J., Auth, Marcus Karl-Heinz, Atkins, Dan, Marderfeld, Luba, Yang, Guan-Yu, Thapar, Nikhil, Dellon, Evan S., Chehade, Mirna, Gutiérrez-Junquera, Carolina   +25 more
core  

Anti‐Inflammatory Activity of Cotula cinerea Essential Oil: Integrated Chemical, In Vivo, Histological, and Computational Evaluation

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Cotula cinerea essential oil was chemically profiled and evaluated in an exploratory in vivo model with histological assessment, while computational analyses generated hypotheses for interactions of selected constituents with COX‐2 and BSA. The predictive findings require direct experimental validation. ABSTRACT The anti‐inflammatory activity of Cotula
Habiba Haddad, Mohammed Larbi Benamor, Yahia Bekkar, Ouafa Boudebia, Salah Neghmouche Nacer, Elhafnaoui Lanez, Aicha Adaika, Taher M. Abdelhameed, Lazhar Bechki, Touhami Lanez, Stefania Garzoli   +10 more
wiley   +1 more source