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Background: Oclacitinib is a Janus kinase inhibitor approved for the treatment of pruritus associated with allergic dermatitis in dogs and may be effective in horses. Objectives: To evaluate the efficacy of oclacitinib in reducing pruritus and skin lesions in horses with allergic dermatitis.
Maturawan Tunhikorn +6 more
wiley +1 more source
Abstract This study investigated Prangos ferulacea (PF)‐induced hepatotoxicity, its potential association with endoplasmic reticulum (ER) stress and proinflammatory cytokines, and the effect of the cannabinoid type 2 receptor agonist JWH‐133. Rats (n = 37) were divided into four groups: control–sham group (CSG, n = 9), PF extract group (PG, n = 9), PF ...
Mesut Çelik +7 more
wiley +1 more source
Localized Eosinophilic Ileitis Presenting As Refractory Pediatric Intestinal Pseudo-Obstruction With Recurrent Ileostomy Prolapse: A Delayed Histopathologic Diagnosis. [PDF]
Cummings-Ruiz IL, Ortiz Justiniano V.
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Eosinophilic Duodenitis and Jejunitis with Ascites and Peripheral Eosinophilia: A Diagnostic Challenge-Case Report. [PDF]
Barboi OB +7 more
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Pediatric Eosinophil-Predominant Collagenous Gastritis: From Conventional Therapy to Dupilumab: A Case Report. [PDF]
Rogalidou M +7 more
europepmc +1 more source
Clinicopathologic Correlations in Eosinophilic Gastrointestinal Disorders
Eosinophilic gastrointestinal disorders (EGIDs) are a collection of disorders characterized by allergy-driven inflammation of the gastrointestinal (GI) tract. Affected patients typically present with nonspecific symptoms of GI dysfunction and are frequently found to have mucosal abnormalities during endoscopy as well as increased eosinophil levels on ...
Margaret H Collins +2 more
exaly +4 more sources
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Eosinophilic gastrointestinal disorders (EGID)
Journal of Allergy and Clinical Immunology, 2004Primary eosinophilic gastrointestinal disorders are defined as disorders that selectively affect the gastrointestinal tract with eosinophil-rich inflammation in the absence of known causes for eosinophilia (eg, drug reactions, parasitic infections, and malignancy).
Marc E. Rothenberg
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Eosinophilic Disorders of the Gastrointestinal Tract
Primary Care - Clinics in Office Practice, 2016Eosinophilic gastrointestinal disorders represent a spectrum of disorders demonstrating gastrointestinal eosinophilia without any known cause for eosinophilia. Pathogenesis is not clearly established, but immune responses to dietary antigens are implicated.
Hadi Bhurgri
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Pharmacological treatment of eosinophilic gastrointestinal disorders
Expert Review of Clinical Pharmacology, 2016Eosinophilic gastrointestinal disorders (EGIDs) are increasingly prevalent chronic inflammatory diseases characterized by eosinophilic infiltration of the gastrointestinal (GI) tract, in the absence of other known causes of eosinophilia.Clinical management of EGIDs is challenging, as there are currently limited therapeutic options available.
Susan Hua, Dane Cook, Marjorie Walker
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Eosinophilic Gastrointestinal Disorders
Clinical Reviews in Allergy & Immunology, 2019Eosinophilic gastrointestinal disorders (EGID) are a group of disorders characterized by pathologic eosinophilic infiltration of the esophagus, stomach, small intestine, or colon leading to organ dysfunction and clinical symptoms (J Pediatr Gastroenterol Nutr; Spergel et al., 52: 300-306, 2011).
Florian, Hentschel, Stefan, Lüth
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