Results 111 to 120 of about 223,805 (190)
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Abstract Objective Pediatric aerodigestive and upper gastrointestinal (UGI) motility disorders are common and may be associated with compromised nutritional status and decreased quality of life. Traditional dietary recommendations for aerodigestive and UGI motility disorders have been rudimentary and largely based upon experience and common sense ...
Khalil El‐Chammas +8 more
wiley +1 more source
International audienceEosinophilic lung diseases comprise eosinophilic pneumonia, which may present with chronic or acute onset, or as Loffler syndrome. The diagnosis of eosinophilic pneumonia relies on clinical imaging and the demonstration of alveolar ...
Vincent Cottin +3 more
core +1 more source
Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley +1 more source
Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
BTK inhibitors suppress malignant B‐cell signaling while simultaneously reshaping immune regulation through effects on T cells and the tumor microenvironment. These mechanisms support combination immunotherapy strategies and also underlie the expanding application of BTK inhibitors in solid tumors, autoimmune and inflammatory diseases.
Miao Sun, Dengju Li, Jia Wei
wiley +1 more source
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang +4 more
wiley +1 more source
We report a case of severe pulmonary vein stenosis presenting with pulmonary consolidation and massive pleural effusion, successfully diagnosed using three‐dimensional computed tomography. ABSTRACT We report a rare case of pulmonary vein stenosis (PVS) presenting with massive pleural effusion 5 months after radiofrequency catheter ablation (RFCA) for ...
Yasuhiko Nikaido +6 more
wiley +1 more source
A 74‐year‐old woman was treated for 7 years as culture‐negative bronchiectasis before palpable purpura, haemoptysis, and acute kidney injury revealed MPO‐ANCA vasculitis with pauci‐immune crescentic glomerulonephritis. Rituximab‐based induction produced near‐complete resolution of the pulmonary consolidations and sustained clinical remission at 15 ...
Andrew Kim +5 more
wiley +1 more source
Nerandomilast‐Associated Pneumonitis With a Positive Rechallenge: A Case Report
Nerandomilast was associated with new bilateral pulmonary opacities and inflammatory deterioration 9 days after treatment initiation in a woman with advanced interstitial lung disease. Withdrawal led to improvement, whereas reduced‐dose re‐exposure was followed by recurrence the next day and repeated improvement after discontinuation.
Toyoshi Yanagihara +4 more
wiley +1 more source

