Results 121 to 130 of about 223,805 (190)

Biomarkers of Pre‐COPD Lung Function Trajectories in Middle Age: A Prospective Study From 1st to 6th Decade

Respirology, Volume 31, Issue 10, Page 993-1002, October 2026.
Identifying impaired lifetime lung function trajectories is key to identifying the preclinical phase of COPD (Pre‐COPD) or prognosis of COPD. We have identified that some circulating established COPD biomarkers differ across ‘pre‐COPD’ lung function trajectories, suggesting that some COPD‐specific pathobiological processes, including inflammation, are ...
Dinh S. Bui, Don Vicendese, Jonathan Pham, Nur Sabrina Idrose, Adrian Lowe, Caroline Lodge, Raisa Cassim, Chamara Senaratna, Gayan Bowatte, Garun Hamilton, Alan James, Paul Thomas, Richard Wood‐Baker, Peter Frith, Gary Anderson, Philip M. Hansbro, Graeme Zosky, George Washko, Michael J. Abramson, Rosa Faner, Alvar Agusti, Jennifer Perret, E. Haydn Walters, Shyamali C. Dharmage   +23 more
wiley   +1 more source

Mefloquine-induced eosinophilic pneumonia

, 2007
Mefloquine has been widely used for prophylaxis and treatment of patients with chloroquine-resistant malaria; the drug is usually well tolerated. Rarely, adverse effects may be severe, including gastrointestinal disturbances, neuropsychiatric reactions ...
Psathakis, K., Constantopoulos, S. H., Nikolopoulou, M. I., Katsenos, S.   +3 more
core  

The Usefulness of Machine Learning Models to Predict Patient‐Reported Outcome Measures in Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 5, Page 598-610, October 2026.
ABSTRACT Background and Objective The treatment available for chronic rhinosinusitis with nasal polyps (CRSwNP) has remained unsatisfactory. Patient‐reported outcome measures (PROMs), capturing patient‐perceived health status and well‐being, are vehicles for measuring and improving the efficacy of care.
Yang Shen, Pan‐Hui Xiong, Bo‐Wen Zheng, Chen‐Xi Li, Jun‐Liang Chen, Yue Gu, Yan‐Han Yang, Tao Lu, Yu‐Cheng Yang   +8 more
wiley   +1 more source

Endobronchial Lesion in Eosinophilic Granulomatosis with Polyangiitis

Iranian Journal of Allergy, Asthma and Immunology, 2017
Eosinophilic granulomatosis with polyangiitis is a systemic vasculitis. It could affect respiratory system, kidney, and central nervous system frequently; however, all body organs could be involved.
Guan-Liang Chen, Chun-Han Wu, Wann-Cherng Perng   +2 more
doaj  

Hepatorenal and Full Blood Count Profiles of Stroke Survivors Compared With Controls: A Case–Control Study

FASEB BioAdvances, Volume 8, Issue 10, October 2026.
In a case–control study of 69 participants (20 stroke survivors, 49 controls; aged 31–78 years) at Tamale Teaching Hospital, Ghana (March–September 2025), venous blood was analyzed for full blood count, liver and renal function. After adjusting for BMI and occupation, stroke survivors showed higher indirect bilirubin (0.143 mmol/L) and MCHC (0.398 g/dL)
Moses Banyeh, Lilian Ayimpoka Atindaana, Felicia Essuman, Alexander Asamoah, Benjamin Kwabena Nyadu, Sinclair Selorm Henyo, Emmanuel Louis Nyaaba, Alfred Dekomwine Bamile, Prosper Bafiil Baneor, Brain Abotsi, Yvonne Aduhene Kwarteng, Prospera Dobara, Tracey Amankwaah, Nketia‐Anim Yeboah, Jennifer Ankamah, Mathias Mbabila Mbah, James Ayamsigiya Akanvae, Abdul‐Wahab Draman, Emmanuel Osei Akoto   +18 more
wiley   +1 more source

Acute eosinophilic pneumonia associated with acute respiratory distress syndrome: case report

, 2004
The Authors present a case of acute eosinophilic pneumonia (AEP) associated with severe acute respiratory distress syndrome in a previously healthy young adult, medicated with nitrofurantoin.
Souto, J, Casanova, PC, Carvalho, L, Baptista, JP, Martins, JP, Pimentel, J, Fernandes, V, Simões, A, Costa, JJ, Almeida e Sousa, JP   +9 more
core   +1 more source

The lung is more than an organ of gas exchange: immunocompetency, platelets and implications for drug discovery

British Journal of Pharmacology, Volume 183, Issue 20, Page 5999-6006, October 2026.
Abstract The lungs have for a long time been recognised as having pharmacological significance as a specific organ to modulate the pharmacokinetics of endogenous substances needed to maintain homeostasis. The lungs are therefore the site of action of certain drugs that act on these homeostatic processes, resulting in systemic effects on the ...
Simon C. Pitchford
wiley   +1 more source

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, Volume 56, Issue 10, Page 1162-1176, October 2026.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies

European Journal of Clinical Investigation, Volume 56, Issue 10, October 2026.
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman, Sreya Rahman, Francesca Polverino, Muhammad Adrish   +3 more
wiley   +1 more source

Oncological Outcomes and Safety Profiles of Adjuvant Nivolumab in Muscle‐Invasive Urothelial Carcinoma

International Journal of Urology, Volume 33, Issue 10, October 2026.
ABSTRACT Objectives Perioperative immunotherapy has become the standard of care in patients with high‐risk muscle‐invasive urothelial carcinoma (MIUC). This study aimed to clarify oncological outcomes and safety profiles of adjuvant nivolumab therapy in MIUC, focusing on upper tract urothelial carcinoma (UTUC).
Satoshi Katayama, Tatsushi Kawada, Keiichiro Mori, Kosuke Iwatani, Shota Inoue, Tomofumi Watanabe, Ichiro Tsuboi, Tomoaki Yamanoi, Takehiro Iwata, Kazuma Tsuboi, Wataru Murao, Tetsuya Nakada, Kohei Ogawa, Akihiro Matsukawa, Takafumi Yanagisawa, Shingo Nishimura, Kensuke Bekku, Koichiro Wada, Takahiro Kimura, Motoo Araki   +19 more
wiley   +1 more source