Results 1 to 10 of about 14,010 (170)

Multiplex PCR to Diagnose Gastrointestinal Infections: Key Limitations in Interpretation. [PDF]

United European Gastroenterol J
ABSTRACT Multiplex polymerase chain reaction (PCR) panels are increasingly used for the evaluation of acute diarrhea, providing rapid and sensitive detection of a broad range of enteric pathogens. However, their widespread adoption has created important interpretive challenges for clinicians.
Tansarli GS, Fang FC.
europepmc   +2 more sources

Demographic characteristics and associated conditions in enteropathogenic Escherichia coli positive patients [PDF]

Gut Pathogens
Background Many studies have examined the epidemiology and risk factors of Enteropathogenic Escherichia coli (EPEC); however, few have focused on the adult population.
Heather Lusby, Stacy G. Beal, Kenneth H. Rand   +2 more
doaj   +2 more sources

A Bifunctional T3SS-Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase. [PDF]

Adv Sci (Weinh)
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Socol Y, Gur-Arie L, Tzarum N, Wellins T, Katsowich N, Ravins M, Bejerano-Sagie M, Cohen K, Livnah O, Adkins JN, Nakayasu E, Savchenko A, Choong YK, Tulsian NK, Machida S, Ben-Yehuda S, Litvak Y, Sivaraman J, Rosenshine I.   +18 more
europepmc   +2 more sources

Allelic variations of intimin virulence gene (eae) in typical and atypical enteropathogenic Escherichia coli isolated from children with and without diarrhea in a rural area of southern Mozambique [PDF]

BMC Infectious Diseases
Background Enteropathogenic Escherichia coli (EPEC) is among the major causes of childhood diarrhea in low- and middle-income countries. The pathogenicity of EPEC strains has been associated with the expression of diverse virulence genes, therefore, it ...
Delfino Vubil, Arlindo Chidimatembue, Marcelino Garrine, Tacilta Nhampossa, Quique Bassat, Sozinho Acácio, Augusto Messa Jr., Inácio Mandomando   +7 more
doaj   +2 more sources

Development of a novel human intestinal model to elucidate the effect of anaerobic commensals on Escherichia coli infection

Disease Models & Mechanisms, 2022
The gut microbiota plays a crucial role in protecting against enteric infection. However, the underlying mechanisms are largely unknown owing to a lack of suitable experimental models.
Conor J. McGrath, Edgaras Laveckis, Andrew Bell, Emmanuelle Crost, Nathalie Juge, Stephanie Schüller   +5 more
doaj   +1 more source

The inhibitory effect of extracts of tea plant and tannins isolated from the growth of E. coli pathogen of isolated intestines from infants with diarrhea Enteropathogenic Escherchia coli (EPEC) in Mosul [PDF]

مجلة التربية والعلم, 2007
This study included isolation and diagnosis of the Enteropathogenic Escherchia coli (EPEC)from diarrhoeal cases in infants.Specimens were collected from(243) patients under 2 years during the period July 2002- March 2003.
Dhekra Al-Taee, Khuder Sulaiman
doaj   +1 more source

Identification of Five Serotypes of Enteropathogenic Escherichia coli from Diarrheic Calves and Healthy Cattle in Belgium and Comparative Genomics with Shigatoxigenic E. coli

Veterinary Sciences, 2022
Enteropathogenic Escherichia coli (EPEC) produce attaching/effacing (AE) lesions and cause non-bloody diarrhea in mammals. A minority of bovine EPEC belong to one of the ten classical serotypes of human and bovine AE-STEC.
Audrey Habets, Fabrice Touzain, Pierrick Lucas, Nguyen Thi Thu Huong, Atsushi Iguchi, Florence Crombé, Nicolas Korsak, Denis Piérard, Marc Saulmont, Eric Cox, Frederik Engelen, Jacques Mainil, Damien Thiry   +12 more
doaj   +1 more source

β-arrestin 2 quenches TLR signaling to facilitate the immune evasion of EPEC

Gut Microbes, 2020
The protein translocated intimin receptor (Tir) from enteropathogenic Escherichia coli shares sequence similarity with the host cellular immunoreceptor tyrosine-based inhibition motifs (ITIMs).
Zijuan Chen, Ruixue Zhou, Yihua Zhang, Doudou Hao, Yu Wang, Shichao Huang, Ningning Liu, Chunmei Xia, Nissan Yissachar, Feng Huang, Yiwei Chu, Dapeng Yan   +11 more
doaj   +1 more source

Transmembrane domains of type III-secreted proteins affect bacterial-host interactions in enteropathogenic E. coli

Virulence, 2021
Many bacterial pathogens utilize a specialized secretion system, termed type III secretion system (T3SS), to translocate effector proteins into host cells and establish bacterial infection. The T3SS is anchored within the bacterial membranes and contains
Jenia Gershberg, Dor Braverman, Neta Sal-Man   +2 more
doaj   +1 more source

MOLECULAR CHARACTERIZATION OF ENTEROPATHOGENIC E. COLI (EPEC) AND SHIGA-TOXIN PRODUCING E. COLI (STEC) FROM DOMESTIC ANIMALS: PREVALENCE, VIRULENCE, COLONIZATION FACTORS AND THEIR ANTIMICROBIAL RESISTANCE [PDF]

Exploratory Animal and Medical Research
To ascertain the presence and molecular characterization of enteropathogenic and Shiga toxin E. coli, 200 fecal samples were collected from rabbits (24), slaughtered pigs (22), calves (39), poultry (41), dogs (38), sheep and goats (36).
Deep Shikha, M.A. Bhat, Indica Sharma, Amitava Paul, Anil Taku   +4 more
doaj   +1 more source