Results 191 to 200 of about 28,018 (244)
Cancer Cell, 2020 Summary Ependymoma is a heterogeneous entity of central nervous system tumors with well-established molecular groups. Here, we apply single-cell RNA sequencing to analyze ependymomas across molecular groups and anatomic locations to investigate their ...
Johannes Gojo +2 more
exaly +2 more sources
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
Cell, 2020 SUMMARY Posterior fossa A (PFA) ependymomas are lethal malignancies of the hindbrain in infants and toddlers. Lacking highly recurrent somatic mutations, PFAs are proposed as an epigenetically driven tumor for which model systems are lacking.
Kulandaimanuvel Antony Michealraj +2 more
exaly +2 more sources
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Seminars in Neurology, 2018
AbstractEpendymoma can arise throughout the whole neuraxis. In children, tumors predominantly occur intracranially, whereas the spine is the most prevalent location in adults. Significant variance in the grade II versus grade III distinction of ependymomas has led to the acknowledgment that the clinical utility of histopathological classification is ...
Matthew C. Ward +2 more
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AbstractEpendymoma can arise throughout the whole neuraxis. In children, tumors predominantly occur intracranially, whereas the spine is the most prevalent location in adults. Significant variance in the grade II versus grade III distinction of ependymomas has led to the acknowledgment that the clinical utility of histopathological classification is ...
Matthew C. Ward +2 more
openaire +3 more sources
Ophthalmic Plastic & Reconstructive Surgery, 2022
Orbital ependymomas are rare in the orbit and usually occur secondary to extracerebral extension of an intraventricular ependymoma. The authors present a rare case of orbital ependymoma in a 74-year-old female. The patient was initially diagnosed with intraventricular ependymoma at the age of 13 years that required multiple repeat craniotomies for ...
Imanouel M, Tsimchi +3 more
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Orbital ependymomas are rare in the orbit and usually occur secondary to extracerebral extension of an intraventricular ependymoma. The authors present a rare case of orbital ependymoma in a 74-year-old female. The patient was initially diagnosed with intraventricular ependymoma at the age of 13 years that required multiple repeat craniotomies for ...
Imanouel M, Tsimchi +3 more
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Tanycytic ependymoma of filum terminale: A case report
Clinical Neurology and Neurosurgery, 2012 Tanycytic ependymoma is an uncommon but well-recognized variant of ependymoma. Here we report a case of tanycytic ependymoma occurring at the region of filum terminale in a 44-year male who presented with low backache, bilateral lower limb weakness and ...
Neelima Radhakrishnan
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Critical Reviews in Oncology/Hematology, 2007
Ependymomas are rare tumours of neuroectodermal origin classified as myxopapillary ependymoma and subependymoma (grade I), ependymoma (grade II) and anaplastic ependymoma (grade III). The more common location is infratentorial (60%). Age
Reni M, Gattab G, Mazza E, Vecht C
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Ependymomas are rare tumours of neuroectodermal origin classified as myxopapillary ependymoma and subependymoma (grade I), ependymoma (grade II) and anaplastic ependymoma (grade III). The more common location is infratentorial (60%). Age
Reni M, Gattab G, Mazza E, Vecht C
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Current Treatment Options in Neurology, 2006
Optimal management of ependymomas includes surgical resection and evaluation of the extent of central nervous system involvement using cerebrospinal fluid cytology and craniospinal contrast-enhanced MRI. In instances of measurable residual disease, reoperation should be considered because survival of patients with ependymomas is significantly improved ...
Sajeel, Chowdhary +2 more
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Optimal management of ependymomas includes surgical resection and evaluation of the extent of central nervous system involvement using cerebrospinal fluid cytology and craniospinal contrast-enhanced MRI. In instances of measurable residual disease, reoperation should be considered because survival of patients with ependymomas is significantly improved ...
Sajeel, Chowdhary +2 more
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Child's Nervous System, 2003
The management of a patient with an ependymoma is controversial. Although the necessity for a multi-disciplined approach is accepted, the exact roles for all disciplines are poorly defined.This review article examines the current status of histopathological and cytogenetic diagnosis, surgical, chemotherapeutic and radiotherapeutic treatment and future ...
Charles, Teo +5 more
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The management of a patient with an ependymoma is controversial. Although the necessity for a multi-disciplined approach is accepted, the exact roles for all disciplines are poorly defined.This review article examines the current status of histopathological and cytogenetic diagnosis, surgical, chemotherapeutic and radiotherapeutic treatment and future ...
Charles, Teo +5 more
openaire +2 more sources
Ultrastructural Pathology, 1994
Twenty-six ependymomas were studied by light and electron microscopy. By electron microscopy, the acellular zones around small vessels in light microscopic sections were seen to be composed of large numbers of closely packed, filament-rich, cytoplasmic processes ringing small vessels.
A, Sara, J M, Bruner, B, Mackay
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Twenty-six ependymomas were studied by light and electron microscopy. By electron microscopy, the acellular zones around small vessels in light microscopic sections were seen to be composed of large numbers of closely packed, filament-rich, cytoplasmic processes ringing small vessels.
A, Sara, J M, Bruner, B, Mackay
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Acta Neuropathologica, 2016 Multiple independent genomic profiling efforts have recently identified clinically and molecularly distinct subgroups of ependymoma arising from all three anatomic compartments of the central nervous system (supratentorial brain, posterior fossa, and ...
KRISTIAN W Pajtler +2 more
exaly +2 more sources