Results 61 to 70 of about 28,018 (244)

Malignant Transformation of Grade II Ependymoma in a 2-Year-Old Child: Case Report

Journal of Neurological Surgery Reports, 2015
Ependymomas are central nervous system neoplasms that account for a third of all posterior fossa tumors in children. The most common location for infratentorial ependymoma is within the fourth ventricle.
Şule Sarıkafa, Suat Erol Çelik, Enver Yarikkaya, Ayşe Sayılgan   +3 more
doaj   +1 more source

EZHIP / CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma.

Neuro-Oncology, 2019
BACKGROUND Posterior fossa A (PFA) ependymomas comprise one out of nine molecular groups of ependymoma. PFA tumors are mainly diagnosed in infants and young children, show a poor prognosis and are characterized by a lack of the repressive histone H3 ...
Jens-Martin Hübner, T. Müller, Dimitris N. Papageorgiou, Monika Mauermann, J. Krijgsveld, R. Russell, D. Ellison, S. Pfister, K. Pajtler, M. Kool   +9 more
semanticscholar   +1 more source

A Phase II Study of Dose-Dense Temozolomide and Lapatinib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma.

Neuro-Oncology, 2020
BACKGROUND No standard medical treatment exists for adult patients with recurrent ependymoma and prospective clinical trials in this population have not succeeded because of its rarity and challenges in accruing patients.
M. Gilbert, Ying Yuan, Jimin Wu, T. Mendoza, Elizabeth Vera, A. Omuro, F. Lieberman, H. Robins, E. Gerstner, Jing Wu, P. Wen, T. Mikkelsen, K. Aldape, T. Armstrong   +13 more
semanticscholar   +1 more source

Comparison of epidemiology, treatments, and outcomes in pediatric versus adult ependymoma

Neuro-Oncology Advances, 2020
Background Mounting evidence supports the presence of heterogeneity in the presentation of ependymoma patients with respect to location, histopathology, and behavior between pediatric and adult patients.
A. Elsamadicy, Andrew B. Koo, Wyatt B. David, V. Lee, C. Zogg, Adam J. Kundishora, Christopher S. Hong, T. DeSpenza, Benjamin C. Reeves, K. Kahle, M. Diluna   +10 more
semanticscholar   +1 more source

YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis

Nature Communications, 2019
YAP1 fusion-positive supratentorial ependymomas predominantly occur in infants, but the molecular mechanisms of oncogenesis are unknown. Here we show YAP1-MAMLD1 fusions are sufficient to drive malignant transformation in mice, and the resulting tumors ...
K. Pajtler, Yiju Wei, K. Okonechnikov, Patricia B. G. Silva, Mikaella Vouri, Lei Zhang, S. Brabetz, Laura Sieber, M. Gulley, Monika Mauermann, T. Wedig, Norman L Mack, Y. Imamura Kawasawa, Tanvi Sharma, Marc Zuckermann, F. Andreiuolo, E. Holland, K. Maass, Huiqin Körkel-Qu, Haikun Liu, F. Sahm, D. Capper, J. Bunt, L. Richards, David T. W. Jones, A. Korshunov, L. Chavez, P. Lichter, M. Hoshino, S. Pfister, M. Kool, Wei Li, D. Kawauchi   +32 more
semanticscholar   +1 more source

Ependymoma in a Rat

Experimental Animals, 1986
Pathological examination was performed on a male 196-day-old Sprague-Dawley rat with hindrance of the motility. A tumor was found to locate in the right lateral ventricle. It was poorly demarcated, and was reddish gray in color. The tumor cells were pleomorphic, fusiform or polygonal in shape and varied in size, sometimes with formation of ...
K, Yamasaki, Y, Fukushima
openaire   +3 more sources

Anatomical Limitation of Posterior Spinal Myelotomy for Intramedullary Hemorrhage Associated with Ependymoma or Cavernous Malformation of the High Cervical Spine

Neurologia Medico-Chirurgica, 2022
Spinal intramedullary tumors such as ependymoma or vascular lesions such as cavernous malformation are often at risk of intramedullary hemorrhage. Surgical procedures involving the high cervical spinal cord are often challenging.
Kohei TSUJINO, Takuya KANEMITSU, Yuichiro TSUJI, Ryokichi YAGI, Ryo HIRAMATSU, Masahiro KAMEDA, Naokado IKEDA, Naosuke NONOGUCHI, Motomasa FURUSE, Shinji KAWABATA, Kentaro NAITO, Toshihiro TAKAMI, Masahiko WANIBUCHI   +12 more
doaj   +1 more source

Brain tumors: Medulloblastoma, ATRT, ependymoma

Pediatric Blood & Cancer, 2020
Children with medulloblastoma, atypical teratoid rhabdoid tumor (ATRT), and ependymoma are treated with a multidisciplinary approach including surgery, radiotherapy, and chemotherapy.
S. Baliga, L. Gandola, B. Timmermann, Horan Gail, L. Padovani, G. Janssens, T. Yock   +6 more
semanticscholar   +1 more source

Supratentorial tanycytic ependymoma: an uncommon fibrillary ependymoma variant

, 2011
[No abstract available]694723Ito, T., Ozaki, Y., Nakamura, H., Tanaka, S., Nagashima, K., A case of tanycytic ependymoma arising from the cerebral hemisphere (2006) Brain Tumor Pathol, 23, pp. 91-95Richards, A.L., Rosenfeld, J.V., Gonzales, M.F., Ashley,
Fabiano Reis, Luciano de Souza Queiroz, Ricardo Schwingel, de Morais F.C., Queiroz L.S., Schwingel R., Francisco Carlos de Morais, Reis F.   +7 more
core   +1 more source

Supratentorial extra-axial RELA fusion-positive ependymoma misdiagnosed as meningioma by intraoperative histological and cytological examinations: a case report

Journal of Medical Case Reports, 2022
Background Dura-attached supratentorial extra-axial ependymoma is a very rare type of tumor, with only nine reported cases. Preoperative diagnosis of dura-attached supratentorial extra-axial ependymoma is difficult and often radiologically misdiagnosed ...
Mayumi Akaki Nagayasu, Tsuyoshi Fukushima, Fumitaka Matsumoto, Hideo Takeshima, Yuichiro Sato, Hiroaki Kataoka   +5 more
doaj   +1 more source