Results 41 to 50 of about 28,018 (244)
Neurosurgery, 2020 Abstract Ependymoma and chordoma are 2 tumors that occur throughout the craniospinal axis, and for which the extent of neurosurgical resection has a key prognostic role. Both tumors have distinctive pathologic features, yet can present significant diagnostic challenges to pathologists in cases without classical histology.
Adrian B Levine +3 more
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Cancers, 2021 Simple Summary Phytocannabinoids Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) have been demonstrated to exhibit anti-cancer activity in preclinical models of brain cancer leading to new clinical trials for adults with glioblastoma.
C. Andradas +12 more
semanticscholar +1 more source
A Rare Case of Metastatic Primary Peritoneal Ependymoma: A Case Report and Literature Review
Case Reports in Oncological Medicine, 2020 Background. Primary peritoneal ependymoma is an exceedingly rare tumour with only four cases reported in the literature. It typically follows an indolent disease course.
Ben Man Fei Cheung +4 more
doaj +1 more source
Pediatric ependymomas: Something old, something new
Pediatric Hematology Oncology Journal, 2023 Ependymoma is one of the most common central nervous system (CNS) tumors in childhood. Ependymoma had previously been considered a single disease entity that arises in the posterior fossa, supratentorial compartment, or spinal cord; however recent ...
David N. Korones
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Myxopapillary Ependymoma of the Cauda Equina in a 5-Year-Old Boy [PDF]
Asian Spine Journal, 2014 Myxopapillary ependymoma in childhood typically occurs in the central nervous system. There are few surgical cases of myxopapillary ependymoma of the cauda equina in children.
Masashi Uehara +9 more
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PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism
Nature Communications, 2019 Posterior fossa type A (PFA) ependymomas exhibit very low H3K27 methylation and express high levels of EZHIP (Enhancer of Zeste Homologs Inhibitory Protein, also termed CXORF67). Here we find that a conserved sequence in EZHIP is necessary and sufficient
Siddhant U. Jain +13 more
semanticscholar +1 more source
Acta Neuropathologica Communications, 2020 We report a novel group of clinically aggressive spinal cord ependymomas characterized by Grade III histology, MYCN amplification, an absence of NF2 alterations or other recurrent pathogenic mutations, and a unique methylation classifier profile.
M. Raffeld +12 more
semanticscholar +1 more source
Turkish Neurosurgery, 2010 Intramedullary tumors affecting the entire cord from the cervicomedullary junction to the conus are termed "holocord tumors". Ependymomas are the most frequent intramedullary tumor in adults. Holocord ependymoma is an exceedingly rare condition. An extensive review of the literature revealed that only five other cases have been reported.
Hamit Feran, Gunes, Nail, Ozdemir
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International Journal of Molecular Sciences, 2021 Childhood ependymomas are heterogenous chemoresistant neoplasms arising from aberrant stem-like cells. Epigenome deregulation plays a pivotal role in ependymoma pathogenesis, suggesting that epigenetic modifiers hold therapeutic promise against this ...
T. Servidei +11 more
semanticscholar +1 more source
Journal of Clinical Oncology, 2019 PURPOSE The Children's Oncology Group trial ACNS0121 estimated event-free survival (EFS) and overall survival for children with intracranial ependymoma treated with surgery, radiation therapy, and-selectively-with chemotherapy. Treatment was administered
T. Merchant +23 more
semanticscholar +1 more source