Results 51 to 60 of about 18,831 (220)

Understanding Consumption of Illicit Drugs and New Psychoactive Substances in Australia by Triangulating Drug Checking and Wastewater‐Based Epidemiology

Drug Testing and Analysis, EarlyView.
First Australian study combining wastewater‐based epidemiology and drug checking, demonstrating how complementary data sources enhance monitoring of illicit drugs and emerging psychoactive substances during high‐use periods. ABSTRACT Consumption of psychotropic drugs is a major economic and public health challenge in Australia.
Muhammad Usman, Malcolm McLeod, Dhayaalini Nadarajan, Joseph Clokey, Pritesh Prasad, Rory Verhagen, Benjamin Tscharke, Maurizio Quinto, Richard Bade   +8 more
wiley   +1 more source

Asymmetric Synthesis of Tertiary α‐Aryl Stereocentres in Tetrahydro‐4H‐pyran‐4‐ones Using Pd‐Catalyzed Decarboxylative Asymmetric Protonation

European Journal of Organic Chemistry, EarlyView.
The Pd‐catalyzed decarboxylative asymmetric protonation (DAP) has been developed for sterically hindered tetrahydro‐4H‐pyran‐4‐one derived α‐aryl‐β‐keto esters. A substrate scope of nine examples of DAP showed that substrates containing a di‐ortho methoxy substitution pattern on the aryl ring gave rise to the highest enantioselectivities of up to 85 ...
Fionn McNeill, Joffrey Scriven, Fritz Bahns, Anugam V. Krishna, Julia Bruno‐Colmenarez, Patrick J. Guiry   +5 more
wiley   +1 more source

Natural language processing‐based emotion and usage analysis of an AI‐powered chatbot for epilepsy support

Epilepsia Open, EarlyView.
Abstract Objective Artificial intelligence (AI)‐powered chatbots are increasingly used for patient education and mental health support, yet their effectiveness in epilepsy care remains underexplored. This study examines text‐based interactions between users and EpiloBot, an epilepsy‐focused chatbot, to understand conversational patterns and emotional ...
Keiichi Watanuki, Ryoya Oba, Naoki Nozawa, Tomoki Ishihara, Koko Oga, Takayuki Iwayama, Takafumi Shiganami, Sayaka Kobayashi, Hironori Kuga, Haruo Yoshimasu, Izumi Kuramochi   +10 more
wiley   +1 more source

Complication Rates Associated With Evolving Practice Patterns in Vasopressor Use and Fluid Administration for Oral Cavity Cancer Free Flap Reconstruction

Head &Neck, EarlyView.
ABSTRACT Background The safety of vasopressors for managing intraoperative hypotension remains debated. This study evaluated complications associated with vasopressor use and fluid administration in oral cavity cancer free flap surgery. Methods Retrospective review of 826 patients who received oral cavity cancer free flap reconstruction from 2008 to ...
Harrison Gao, Nuwan Dharmawardana, Alex O. Esemezie, Hedyeh Ziai, Philopateer Ataalla, Natalie Weisbrod, Konrado Deutsch, Stuart A. McCluskey, Danny Enepekides, Kevin M. Higgins, Antoine Eskander, John R. de Almeida, David P. Goldstein, Ralph W. Gilbert, Jonathan C. Irish, Dale H. Brown, Christopher M. K. L. Yao, Christopher W. Noel, Sharon Tzelnick   +18 more
wiley   +1 more source

Ephedrine: direct, indirect or mixed acting sympathomimetic? [PDF]

, 2017
Ephedrine is the principal alkaloid that is responsible for the physiological effects of herb ephedra. This herb is found in literature of India and China since ancient times because of its effectiveness as an anti-asthmatic.
Kantharia, Naresh D., Yadav, Preeti P., Solanki, Paresh   +2 more
core  

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Prophylactic effect of ephedrine to reduce hemodynamic changes associated with anesthesia induction with propofol and remifentanil

Journal of Anaesthesiology Clinical Pharmacology, 2014
Background: One of the complications of anesthesia induction with propofol is a substantial decrease in arterial blood pressure and heart rate (HR), which can be intensified by adding remifentanil.
Mansoor Masjedi, Farid Zand, Asif Perviz Kazemi, Ali Hoseinipour   +3 more
doaj   +1 more source

Therapeutic‐dose verapamil‐induced cardiogenic shock in an older patient: a case report

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Calcium channel blocker (CCB) toxicity most commonly follows deliberate overdose. However, severe toxicity at therapeutic doses may occur in susceptible individuals. Severe CCB toxicity often presents with clinical features of bradycardia, hypotension, hyperglycaemia, and lactic acidosis.
Christopher Thuring, Maria Carey, Timothy Webber, Biswadev Mitra   +3 more
wiley   +1 more source

Urinary Excretion of Ephedrine After Nasal Application in Healthy Volunteers

, 1992
The urinary excretion of ephedrine after intranasal administration of the drug was studied in 8 healthy volunteers. Ephedrine (6 drops of a commercial 0·75% nasal ephedrine solution in each nasal cavity) was administered 4 times at intervals of 2 h ...
E Moerman, R A Lefebvre, J Bouckaert, F Surmont   +3 more
core   +1 more source

Intraoperative Bradycardia: Evaluating Vasovagal Events in Adult Suspension Microlaryngeal Surgery

The Laryngoscope, EarlyView.
This retrospective single‐surgeon cohort study of 190 adults undergoing suspension microlaryngoscopy found that 8.9% (17/190) developed significant intraoperative bradycardia consistent with a vasovagal response (VVR). No demographic, comorbidity, or procedural factors were significantly associated with VVR, though most affected patients required ...
Thomas Q. McClelland, Cyrus W. Abrahamson, Abbey L. Landini, Andrew P. Stein, James A. Burns   +4 more
wiley   +1 more source