Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley +1 more source
OutFOXed: FOXJ3 Variants Disrupt PTEN-mTOR Signaling in Focal Epilepsy. [PDF]
Bedrosian TA.
europepmc +1 more source
Modeling the Intermediate Flow Regime in Flow‐Compensated Intravoxel Incoherent Motion MRI
ABSTRACT Purpose The intravoxel incoherent motion (IVIM) model is commonly used to separate the effects of motion related to diffusion and blood microcirculation (perfusion) on the MR signal. Depending on the encoding time (T), it is possible to probe the different temporal regimes of blood motion, which resemble a ballistic flow at short T and a ...
Louise Rosenqvist +5 more
wiley +1 more source
Apparent diffusion coefficient as a quantitative biomarker for prostate cancer treatment response on a 1.5 Tesla magnetic resonance-linear accelerator: Impact of image registration and acquisition type. [PDF]
Nair PP +9 more
europepmc +1 more source
Echo‐Planar‐Based Time‐of‐Flight Imaging Using a Modified Interleaved Flyback Trajectory
ABSTRACT Purpose A modified interleaved flyback (miFB) approach is introduced, designed to mitigate flow artifacts caused by alternating readout polarities in Echo Planar Imaging (EPI), while preserving acquisition efficiency. Methods We propose reconstructing odd and even echoes of 3D‐EPI separately.
Simon Blömer +2 more
wiley +1 more source
Boundary-guided cell alignment drives mouse epiblast maturation. [PDF]
Ichikawa T +9 more
europepmc +1 more source
ABSTRACT Purpose Diffusion MRI probes tissue microstructure, but low SNR and limited resolution hinder detection of features and parameter estimates. We introduce slice excitation with random overlap (SERO), which enables variable repetition times (TRs) and diffusion weighting within a single shot.
Felix Mortensen +7 more
wiley +1 more source
Low-Cost and Fast Epiretinal Membrane Detection and Quantification Based on SD-OCT. [PDF]
Baek S, Lee I, Jang KJ, Han Y, Kim JH.
europepmc +1 more source
EPI-DOM framework for assessing fish welfare: external and internal indicators for tilapia. [PDF]
Martínez-Yáñez R.
europepmc +1 more source
Elastoplasticity Informed Kolmogorov–Arnold Networks Using Chebyshev Polynomials
ABSTRACT Multilayer perceptron (MLP) networks are predominantly used to develop data‐driven constitutive models for granular materials. They offer a compelling alternative to traditional physics‐based constitutive models in predicting non‐linear responses of these materials, for example, elastoplasticity, under various loading conditions. To attain the
Farinaz Mostajeran, Salah A. Faroughi
wiley +1 more source

