Results 121 to 130 of about 247,347 (264)

Identification of major congenital malformations based on healthcare databases in France: A proof‐of‐concept study using the epi‐meres nationwide mother–child register

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Besides registries, healthcare databases can provide useful information for assessing the frequency of major congenital malformations (MCMs) and investigating their risk factors, particularly medication exposures. This study aimed to assess the validity of MCMs identification based on French national, comprehensive healthcare databases ...
Tom Duchemin, Lise Marty, Jérôme Drouin, Sara Miranda, Jérémie Botton, Valérie Olié, Alain Weill, Rosemary Dray‐Spira   +7 more
wiley   +1 more source

Improved image quality and T-staging accuracy using FOCUS-MUSE DWI in gastric cancer: a prospective comparison with SS-EPI. [PDF]

Eur Radiol Exp
Li Q, Hou YJ, Jiang QY, Xu J, Feng QX, Yuan L, Wu PY, Wu CJ, Liu XS, Sun NN.   +9 more
europepmc   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

Exocrine Pancreatic Insufficiency in Diabetes: Association with Cardiovascular Disease and Insulin Therapy. [PDF]

J Clin Med
Balamir M, Avcı B, Coşan E, Tanyolaç S, Çavuş B, Örmeci AÇ, Akyüz F, Beşışık SF, Kaymakoğlu S, Hacısahinogullari H, Sarıbeyliler G, Çakmak R, Karşıdağ K, Çetin Ş, Demir K.   +14 more
europepmc   +1 more source

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

British Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu, Pier Giorgio Cojutti, J. G. Coen van Hasselt, Michele Bartoletti, Maddalena Giannella, Pierluigi Zinzani, Pierluigi Viale, Federico Pea   +7 more
wiley   +1 more source

Exploring the antimalarial potential of (+)-2,2'-epicytoskyrin A: in vitro and in vivo studies of a bioactive metabolite from endophytic fungus Diaporthe sp. GNBP-10. [PDF]

Malar J
Novita R, Fathoni A, Waluyo D, Suprayogi A, Darusman HS, Nugraha AB, Nurkanto A, Ilmi H, Nozaki T, Agusta A.   +9 more
europepmc   +1 more source

The effect of mild and moderate hepatic impairment on the pharmacokinetics, safety and tolerability of balcinrenone

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Balcinrenone (previously AZD9977) is a novel selective non‐steroidal mineralocorticoid receptor antagonist (MRA) with a differential mechanism of action relative to approved MRAs. The aim of this trial was to assess the pharmacokinetics, safety and tolerability of balcinrenone in participants with mild and moderate hepatic impairment ...
Anna L. Eriksson, Deeyen Karsanji, Bonifride Tuyishimire, Joanna Parkinson, Maria Heijer, Tadeusz Pawlik, Judith Hartleib‐Geschwindner, Maria Leonsson‐Zachrisson, Hans Ericsson   +8 more
wiley   +1 more source

A novel distortion-matched anatomical imaging sequence for high-fidelity functional mapping in submillimeter-resolution fMRI. [PDF]

Sci Rep
Yun SD, Pais-Roldán P, Lee J, Shah NJ.
europepmc   +1 more source

Falling pupil numbers and school closures: Setting a research agenda for a new era of precarity

British Educational Research Journal, EarlyView.
Abstract This paper explores the significant phenomenon of decreasing pupil numbers in England due to lower birth rates and the impact of a school closure on a school community. It then discusses how the sociology of education might research this major issue.
Eleanor Fagan, Alice Bradbury
wiley   +1 more source

Clinical risk factors of licorice-induced pseudohyperaldosteronism: a 2026-updated narrative review. [PDF]

Front Pharmacol
Yoshino T, Makino T.
europepmc   +1 more source