Ventral anterior thalamic dysfunction distinguishes seizure generalization in temporal lobe epilepsy
Abstract Objective Focal‐to‐bilateral tonic–clonic seizures (FBTCS) in temporal lobe epilepsy (TLE) involve thalamocortical networks, yet the functional integrity and role of specific thalamic subregions in seizure generalization remain unclear. In this cross‐sectional study, we investigated whether thalamic subregion functional connectivity patterns ...
Stacy N. Hudgins +3 more
wiley +1 more source
Study variation in estimating Glomerular Filtration Rate (GFR) from serum creatinine, cystatin C, age, and sex. [PDF]
Fino N +6 more
europepmc +1 more source
Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis
Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx +192 more
wiley +1 more source
Fast Submillimeter Whole-Brain T<sub>2</sub>*-Weighted Imaging Using 3D-EPI With CAIPIRINHA and Deep-Learning Denoising at 3T. [PDF]
Nair SM +28 more
europepmc +1 more source
Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms
Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong +4 more
wiley +1 more source
Impact of Equation Choice on Models Assessing the Association Between Lipoprotein(a) and Estimated Glomerular Filtration Rate in Adult Patients Without Chronic Kidney Disease. [PDF]
Gencheva-Angelova I, Nuneva-Doncheva R.
europepmc +1 more source
Abstract Objective Despite elevated risk for epilepsy following traumatic brain injury (TBI), there are limited tools to assess epilepsy risk following TBI using routine clinical data. The objective of this study was to develop and validate a machine learning approach to predict the onset of posttraumatic epilepsy (PTE) over varying time horizons ...
Mustafa Ozmen +6 more
wiley +1 more source
Task-Evoked Functional Activation and Coupling With CSF Flow Detected in the Human Brain With Ultrashort Echo Time fMRI at 7 T. [PDF]
Ponticorvo S +7 more
europepmc +1 more source
Abstract Objective The polygenic risk score (PRS) for individuals with genetic generalized epilepsy (GGE) quantifies the common risk variants in genes identified in genome‐wide association studies. We hypothesized that the phenotype of GGE patients differs based on their GGE PRS. Methods We identified participants with highest (n = 59) versus lowest (n
Sophie von Brauchitsch +27 more
wiley +1 more source

