Results 71 to 80 of about 255,159 (264)

Immunogenicity evaluation of primary polio vaccination schedule with inactivated poliovirus vaccines and bivalent oral poliovirus vaccine

BMC Infectious Diseases
Background To assess the immunogenicity of the current primary polio vaccination schedule in China and compare it with alternative schedules using Sabin or Salk-strain IPV (sIPV, wIPV).
Jiawei Xu, Yang Liu, Wei Qiu, Wenwen Li, Xiaoxiao Hu, Xia Li, Qiang Fan, Wenge Tang, Yujie Wang, Qing Wang, Ning Yao   +10 more
doaj   +1 more source

TED1 Promotes the Assembly of SCFD3‐D14‐D53 to Reinforce Strigolactone Signaling in Rice

Advanced Science, EarlyView.
This study identifies TED1 as a positive regulator of strigolactones (SL) signaling in rice. The ted1 mutants display dwarfism and increased tillering with significantly reduced SLs sensitivity. Through its longer C‐terminal region, TED1 interacts with D53 and D14 to promote the assembly of SCFD3‐D14‐D53, thereby facilitating the efficient ...
Sheng Luo, Chuanyin Wu, Miao Feng, Wenfan Luo, Rong Miao, Jinsheng Qian, Fan Wang, Chunlei Zhou, Bojuan Liu, Jiale Shao, Ziqi Xun, Yehui Xiong, Zhichao Zhao, Cailin Lei, Shanshan Zhu, Yulong Ren, Xin Wang, Xiuping Guo, Haiyang Wang, Zichao Li, Zhijun Cheng, Qibing Lin, Jianmin Wan   +22 more
wiley   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

Trends and factors associated with delivery hospitalizations involving severe maternal morbidity in portuguese public hospitals: A population-based study (2010–2018)

Scientific Reports
This study aimed to estimate Severe Maternal Morbidity (SMM) rates and trends among public hospital deliveries in Portugal, 2010–2018, and identify associated factors.
Catarina Camarinha, Maria Miguel Oliveira, Miguel de Araújo Nobre, Cristina Furtado, Cecília Elias, Leonor Bacelar-Nicolau, Andreia Silva Costa, Paulo Jorge Nogueira   +7 more
doaj   +1 more source

HPV vaccination intention among guardians of female secondary school students in Chongqing, China

Human Vaccines & Immunotherapeutics
Background: In China, Chongqing is the first province implement a province-wide HPV vaccination free program for female students. Given the HPV vaccination of adolescents is largely dependent on the intent of their guardians, this study examined the ...
Ningpei Bai, Qing Wang, Jianchao Shao, Lei Chen, Chenglian Wang, Xiao Xiao, Linling Yu, Binyue Xu   +7 more
doaj   +1 more source

Inverse Design of Pre‐Strain via a Predictive Electromechanical Model for Enhanced Strain Sensing

Advanced Science, EarlyView.
An analytical electromechanical model rooted in microcrack evolution mechanics is globally calibrated from only eight pre‐strain datasets, enabling prediction of the complete sensing response at untested pre‐strain values within the calibrated design space (R2 > 0.99).
Jia‐Chen Shang, Rui Wang, Bo Lu, Ming‐Liang Song, Yu‐Yi Chen, Kuo Han, Xin‐Jie Feng, Bin Sun, Yao‐Guang Cao, Xiao‐Yu Yan, Shi‐Chun Yang   +10 more
wiley   +1 more source

Analisa Strategi Pengelolaan Taman Nasional Gede Pangrango (TNGP) Untuk Pengembangan Pariwisata Alam Di Kawasan Hutan.

Jurnal Penelitian Sosial dan Ekonomi Kehutanan, 2014
Pengembangan pengelolaan Taman Nasional Gede Pangrango (TNGP) merupakan bagian integral dari pembangunan kepariwisataan nasional, selain daripada itu pengembangan pengelolaan Taman Nasional Gede Pangrango ini memiliki arti yang sangat penting dan ...
Epi Syahadat
doaj   +1 more source

Multitargeting epi-epi drugs for multidrug reistance [PDF]

, 2020
Epigenetic therapy is now a clinical reality with eight approved drugs that target DNA methyltransferases, histone deacetylases (HDACs) and lysine methyltransferases. A further recent development is the concept of epigenetic multitargeting through the rational design of novel agents that combine the inhibition of an epigenetic pathway with a second non-
Lee, Adam, Ganesan, A., Bulut, İpek, Açılan Ayhan, Ceyda, Ružić, Dušan, Nikolić, Katarina, Gul, Sheraz   +6 more
openaire  

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

A post-marketing safety surveillance study on vaccines in Chongqing, China from 2006 to 2021: Using a nationwide spontaneous reporting database with multiple data mining methods

Human Vaccines & Immunotherapeutics
The Chinese National Adverse Events Following Immunization Information System (CNAEFIS) is the national-level passive vaccine safety surveillance system.
Binyue Xu, Qing Wang, Jiawei Xu, Jianqiao Li, Ningpei Bai   +4 more
doaj   +1 more source