Results 81 to 90 of about 247,347 (264)

A post-marketing safety surveillance study on vaccines in Chongqing, China from 2006 to 2021: Using a nationwide spontaneous reporting database with multiple data mining methods

open access: yesHuman Vaccines & Immunotherapeutics
The Chinese National Adverse Events Following Immunization Information System (CNAEFIS) is the national-level passive vaccine safety surveillance system.
Binyue Xu   +4 more
doaj   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

open access: yesAdvanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu   +7 more
wiley   +1 more source

STRATEGI PEMBANGUNAN HUTAN TANAMAN DI PROVINSI KALIMANTAN TIMUR

open access: yesJurnal Penelitian Sosial dan Ekonomi Kehutanan, 2014
Kebutuhan kayu untuk bahan baku industri di Indonesia tercatat 50-60 juta m³ per tahun, di mana sekitar 30 juta m³ adalah untuk keperluan industri pulp dan kertas. Sebagian besar kebutuhan kayu bulat tersebut masih di pasok dari hutan alam.
Epi Syahadat
doaj   +1 more source

Label‐Free Myelin Fingerprinting: An Adult Human Post‐Mortem Brain Slice Platform via Coherent Anti‐Stokes Raman Spectroscopy

open access: yesAdvanced Science, EarlyView.
A serum‐free, air–liquid interface organotypic slice culture model preserves human post‐mortem corpus callosum tissue, successfully recovering from slicing trauma to reflect the donor's underlying disease state. Pairing label‐free Coherent anti‐Stokes Raman scattering (CARS) microscopy with k‐means clustering enables objective, high‐resolution ...
Kasra Roya‐Kouchaki   +5 more
wiley   +1 more source

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

open access: yesAdvanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma   +22 more
wiley   +1 more source

High-Order Time Discretization of The Wave Equation by Nabla-P Scheme.*

open access: yesESAIM: Proceedings and Surveys, 2014
High-order Discontinuous Galerkin Methods (DGM) are now routinely used for simulation of wave propagation, especially for geophysical applications.
Barucq Hélène   +3 more
doaj   +1 more source

DDSurfer: A Weakly‐Supervised Dual‐Stream Deep Learning Framework for Cortical Surface Reconstruction From Diffusion MRI

open access: yesAdvanced Science, EarlyView.
DDSurfer reconstructs cortical surfaces directly from diffusion MRI without requiring T1‐weighted scans. By fusing complementary microstructural features and learning diffeomorphic deformations, it efficiently generates accurate white matter and pial surfaces, improving geometric fidelity and morphometric reliability across datasets for robust surface ...
Chengjin Li   +10 more
wiley   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

open access: yesAdvanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang   +7 more
wiley   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

open access: yesAdvanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan   +12 more
wiley   +1 more source

Estimating time-varying cholera transmission and oral cholera vaccine effectiveness in Haiti and Cameroon, 2021−2023

open access: yesBMJ Open
Background In 2023, cholera caused over 95 000 deaths globally, predominantly in low-income and conflict settings, and contributed to the wasting, stunting and malnutrition of millions in countries where the disease is endemic.
Maimuna S Majumder   +6 more
doaj   +1 more source

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