Results 161 to 170 of about 383,213 (283)

Longitudinal Analysis of Oral Potentially Malignant Disorder Conversion to Malignancy

The Laryngoscope, EarlyView.
ABSTRACT Objectives Oral potentially malignant disorders (OPMDs) are local and systemic conditions that can result in oral malignancies. We have had an OPMD surveillance program for 25 years covering over 30% of our state's population. More recent electronic health record search techniques have allowed us to analyze over 1500 patients in over a 10‐year
Benjamin Palatnik, Lindsey Mortensen, Aleksandr Palatnik, Beverly R. Wuertz, Frank G. Ondrey   +4 more
wiley   +1 more source

Cell type-specific inference from bulk RNA-sequencing data by integrating single-cell reference profiles via EPIC-unmix. [PDF]

Genome Biol
Tang C, Sun Q, Zeng X, Li G, Yang X, Liu F, Zhao J, Shen Y, Liu B, Wen J, Li Y.   +10 more
europepmc   +1 more source

Optimizing Dizziness Management: Impact of Audiology Triage on Care Efficiency

The Laryngoscope, EarlyView.
ABSTRACT Objectives To evaluate the impact of a vestibular audiology‐driven triage system on care efficiency for patients presenting with dizziness. Methods We conducted a retrospective review of all patients who underwent comprehensive Balance Function Testing (BFT) at the University of Pennsylvania vestibular clinic between September 2019 and June ...
Sanjena Venkatesh, Daniel S. Talian, Kim Le, Archer R. Schaeffer, Keshav Shah, Tanvi Garneni, Christian Jung, Sherrie Davis, Michael J. Ruckenstein, Douglas C. Bigelow, Tiffany P. Hwa   +10 more
wiley   +1 more source

Exploring end-to-end earthquake early warning performance in large earthquakes using the February 2023 Kahramanmaraş, Türkiye sequence. [PDF]

Sci Rep
Marcou S, Lux AI, Akimov A, Williamson AL, Allen RM.   +4 more
europepmc   +1 more source

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

Med Research, EarlyView.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu, Aihetaimujiang Anwaier, Qintao Ge, Siqi Zhou, Xi Tian, Shuxuan Zhu, Guohai Shi, Yu Zhu, Dingwei Ye, Mierxiati Abudurexiti, Hailiang Zhang   +10 more
wiley   +1 more source

Delayed Disease Onset Report in UK Biobank: Implications for Prodromal Studies in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background UK Biobank (UKBB) provides extensive genetic, imaging, and health data for ~500,000 participants, enabling studies of prodromal phases of diseases like Parkinson's disease (PD). However, during analysis, we became concerned about the accuracy of diagnosis timing.
Sheida Zolfaghari, Trycia Kouchache, Aline Delva, Sarah Bouhadoun, Mirja Kuhlencord, Amélie Pelletier, Alastair J. Noyce, Sheena Waters, Daniel Belete, Tim Wilkinson, Kathryn Bush, Filip Morys, Andrew Vo, Kristiina Rannikmae, Alain Dagher, Ronald B. Postuma   +15 more
wiley   +1 more source

Dietary nitrosyl-heme from processed meats and its association with colorectal cancer risk: findings from the EPIC cohort study. [PDF]

Nutr J
Rizzolo-Brime L, Lujan-Barroso L, Farran-Codina A, Bou R, Nicolas G, Huybrechts I, Lasheras C, Montes EM, Colorado-Yohar S, Gasque A, Dahm CC, Bock N, Olsen A, Tjønneland A, Katzke V, le Cornet C, Schulze MB, Saieva C, Sieri S, De Magistris MS, Tumino R, Macciotta A, Wareham N, Weiderpass E, Chatziioannou C, Vineis P, Jakszyn P.   +26 more
europepmc   +1 more source

Serum zinc level independently predicts need for inpatient intubation among patients hospitalized with COVID‐19: A prospective observational study

Nutrition in Clinical Practice, EarlyView.
Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic caused significant morbidity and mortality. Further study of modifiable factors influencing COVID‐19 severity and outcomes continues to be necessary. Serum zinc levels may play a role in modulating COVID‐19 virus replication and consequently influence clinical outcomes.
Scott W. McPherson, Frederik J. van Kuijk, Solmaz Ramezani, Susan Vitale, William H. Amundson, Andrew Caraganis, Kathleen S. Mahan, Rusdeep Mundae, Ronald A. Reilkoff, Emily Y. Chew, David A. Wacker   +10 more
wiley   +1 more source

Nanopore sequencing enables combined detection of <i>USP7</i> variants and a known Hao-Fountain syndrome episignature. [PDF]

Front Genet
van der Laan L, Haagmans MA, Venema A, Kerkhof J, Levy MA, Briuglia S, Caro P, Sailer S, Schaaf CP, Sadikovic B, van Haelst MM, van Gijn M, Alders M, Henneman P.   +13 more
europepmc   +1 more source