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Human epicardial adipose tissue: A review
American Heart Journal, 2007We discuss the anatomy, physiology, and pathophysiology of epicardial adipose tissue and its relationship to coronary atherosclerosis. Epicardial fat stores triglyceride to supply free fatty acids for myocardial energy production and produces adipokines. It shares a common embryological origin with mesenteric and omental fat.
Harold S, Sacks, John N, Fain
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Epicardial Adipose Tissue in Cardiovascular Disease
2019Cardiovascular disease (CVD) is the main cause of morbidity and mortality in industrialized countries, despite the evolution of treatments and revascularization strategies. Obesity, also accompanied by a chronic inflammatory process, is an independent risk factor for CVD. Abdominal adipose tissue is a complex, metabolically very active organ capable of
Berg, Gabriela Alicia +3 more
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Clinical Role of Epicardial Adipose Tissue
Canadian Journal of CardiologyAlthough the epidemic of atherosclerosis has slowed down in industrialized nations, it has increased in speed and severity in developing countries. The worldwide expanding incidence and prevalence of obesity, insulin resistance, and diabetes mellitus may be among the most important drivers of this trend, and the role of visceral adipose tissue as a ...
Paolo Raggi, Arthur E. Stillman
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Epicardial Adipose Tissue Thickness in Hemodialysis Patients
Echocardiography, 2013AimHemodialysis (HD) patients had higher cardiovascular mortality and it is related to atherosclerosis. Epicardial adipose tissue (EAT) thickness is a marker of atherosclerosis and independent predictor of coronary artery disease. The aim of our study was to evaluate the relationship between EAT and carotid intima‐media thickness (CIMT) predictors of ...
BARUTÇU, AHMET +10 more
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Epicardial adipose tissue, hepatic steatosis and obesity
Journal of Endocrinological Investigation, 2007Hepatic steatosis is a common companion of obesity. Moreover, the measurement of epicardial adipose tissue (EAT) has been reported to be related with both obesity and insulin resistance. Therefore, we aimed to evaluate the relationship between hepatic steatosis, EAT and insulin resistance in obese patients.Sixty-three obese subjects were enrolled in ...
A Sertkaya, Cikim +8 more
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Cardiometabolic Risk and Epicardial Adipose Tissue
2020Epicardial adipose tissue (EAT) is a quantifiable and modifiable biomarker. EAT is a marker of visceral adiposity and strongly correlates with fatty liver infiltration and insulin resistance. EAT has shown to correlate and predict the risk of developing the metabolic syndrome, although there is no consensus on the EAT threshold risk values, yet. Higher
Gianluca Iacobellis +1 more
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Targeting the Epicardial Adipose Tissue
2020Epicardial fat (EAT) is the visceral fat depot of the heart. Given its rapid metabolism, organ fat specificity, and simple objective measurability, epicardial fat can serve as a target for pharmaceutical agents targeting the adipose tissue. EAT has shown to significantly respond to thiazolidinediones (TZD), glucagon-like peptide-1 receptor (GLP-1R ...
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Epicardial adipose tissue and atherogenesis
AIDS, 2014Cardiovascular disease (CVD) is increasingly recognized among HIV-infected patients, and carefully performed cohort studies show increased relative risk ratios of 1.5–2.0 [1,2]. Moreover, these studies suggest that traditional risk factors, while accounting for some degree of this increase in relative risk, do not account for all or even a major ...
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Heart Failure and Epicardial Adipose Tissue
2020Epicardial adipose tissue (EAT) has been investigated in patients with both systolic and diastolic heart failure and suggested to play a pathogenic role, although results are not univocal. Experimental studies suggest a potential protective role of the brown fat features of EAT against the systolic heart failure.
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Perivascular and epicardial adipose tissue
Vascular PharmacologyLina, Badimon +5 more
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