Results 81 to 90 of about 10,363 (197)

GLP‐1‐Based Therapies in Type 1 Diabetes: Emerging Evidence on Cardiovascular, Renal, and Safety Outcomes

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 8757-8768, October 2026.
ABSTRACT Background Individuals living with type 1 diabetes (T1D) are at increased risk for cardiovascular (CV) and renal complications, yet therapeutic strategies specifically targeting cardiorenal risk reduction in this population remain limited. The role of glucagon‐like peptide‐1 (GLP‐1)‐based therapies in T1D remains unclear.
Anastasios Tentolouris, Djordje S. Popovic, Alexandros L. Liarakos, Alexandros Briasoulis, Nikolaos Papanas, Theocharis Koufakis   +5 more
wiley   +1 more source

Effect of epicardial adipose tissue on chronic kidney disease

Linchuang shenzangbing zazhi, 2020
Under physiological conditions,epicardial adipose tissue can secrete adipokines with cardioprotective properties.Under pathological conditions,the biologically active molecules secreted by it will promote atherosclerosis and myocardial fibrosis,thus ...
SHAO Cai-rong, YANG Xiao-juan
doaj  

Epicardial Adipose Tissue and its Emerging Importance

Pakistan Journal of Medicine and Dentistry
It is an emerging concept now a day that epicardial adipose tissue (EAT) thickness has an essential character in the progression for cardiac risk profile. It is now consider as a new and consistent cardiovascular risk factor.
Sadaf Shaheen, Nuzhat Hassan, Mohammed Asad Bilal Awan, Nosheen Zehra   +3 more
doaj  

Presumed Primary Cardiac Angiosarcoma With Atrioventricular Groove Rupture and Right Coronary Artery Compromise: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Primary cardiac angiosarcoma should be considered in patients with hemorrhagic pericardial effusion and a right‐sided infiltrative cardiac mass. Atrioventricular‐groove involvement may cause rupture and right coronary artery compromise, requiring multimodality imaging and emergency salvage surgery; early multidisciplinary planning is essential
Farideh Akbari, Rezayat Parvizi, Mobin Mobadersani, Alireza Motamedi, Elnaz Javanshir, Shahla Meshgi, Amir Ghasemi Jangjoo, Reza Bagheri, Nasrin Gholami, Esmaeil Gharepapgh, Sahar Rezaei, Amir Faravan   +11 more
wiley   +1 more source

Plasma Exosome Metabolomics Reveal Stage‐Specific Alterations in Elderly Women With Premetabolic and Metabolic Syndrome

Chronic Diseases and Translational Medicine, Volume 12, Issue 3, Page 219-230, September 2026.
Shared differential metabolites identified across the three sample groups. (A) Venn diagram of differential metabolites between the two comparison groups; Based on the detected levels of these overlapping differential metabolites, (B) d‐Arabitol, (C) Triclosan, (D) Iloprost, (E) Tetracosanoic acid, and (F) Omeprazole sulfone. Box plots were constructed
Mengtao Qian, Dan Nie, Qianyi Gao, Xingbo Mo, Huan Zhang   +4 more
wiley   +1 more source

The Association Between Atherogenic Index of Plasma and Type 2 Diabetes Mellitus in a Multi‐Ethnic Population of Premature Coronary Artery Disease Patients: Insights From IPAD Study

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
In patients with premature coronary artery disease, higher atherogenic index of plasma was associated with prevalent type 2 diabetes and higher fasting blood sugar. Exploratory analyses suggested possible ethnicity‐related heterogeneity, while ROC analysis showed limited discrimination, supporting cautious interpretation rather than clinical screening ...
Reza Amani‐Beni, Ghazal Ghasempour Dabaghi, Noushin Mohammadifard, Ehsan Zarepur, Bahar Darouei, Mehrdad Rabiee Rad, Fahimeh Haghighatdoost, Fatemeh Nouri, Nizal Sarrafzadegan   +8 more
wiley   +1 more source

Epicardial Fat, Paracrine-mediated Inflammation and Atrial Fibrillation

Journal of Interdisciplinary Medicine, 2017
Atrial fibrillation is the most frequent arrhythmia in adults, becoming more frequent with age. Recent clinical studies demonstrated that epicardial fat is linked with atrial fibrillation induction and recurrence. The arrhythmogenic mechanism consists in
Rat Nora, Mitre Adriana, Korodi Szilamér, Benedek István, Lázár Erzsébet, Kéri Johanna, Pakucs Annamária, Benedek István   +7 more
doaj   +1 more source

Tirzepatide and SGLT2 Inhibitors for Heart Failure With Preserved Ejection Fraction and Obesity: Entering a New Cardiometabolic Therapeutic Era

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Tirzepatide and SGLT2 inhibitors act through distinct but complementary mechanisms in obesity‐related HFpEF: tirzepatide targets adiposity, inflammation, and insulin resistance, while SGLT2 inhibitors improve decongestion, myocardial energetics, and cardiac remodeling.
Zakariye Isak Mohamed, Abdinasir Adam Shidane, Abdullahi Mohamud Abdiasis, Mohamed Hassan Hussein, Ayaanle Osman Ibrahim, Anas Ali Abdi, Kowthar Ismail Hashi, Mohamed Abdullahi Mohamud, Ali Jimale Mohamed   +8 more
wiley   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

Med Research, Volume 2, Issue 3, Page 484-497, September 2026.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang, Fen Yang, Xingji Lian, Jie He, Shuijin Huang, Mingjuan Fan, Yin Liang, Jiaqiang Huang, LongYan Yin, Hong Wang   +9 more
wiley   +1 more source

Disease–treatment interactions in the management of patients with obesity and diabetes who have atrial fibrillation: the potential mediating influence of epicardial adipose tissue

Cardiovascular Diabetology, 2019
Both obesity and type 2 diabetes are important risk factors for atrial fibrillation (AF), possibly because they both cause an expansion of epicardial adipose tissue, which is the source of proinflammatory adipocytokines that can lead to microvascular ...
Milton Packer
doaj   +1 more source