Results 81 to 90 of about 19,087 (225)

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Epicardial adipose tissue and pericoronary fat thickness measured with 64-multidetector computed tomography: potential predictors of the severity of coronary artery disease

Clinics, 2014
OBJECTIVE:The aim of the present study was to investigate the relationship between pericoronary fat and the severity and extent of atherosclerosis, quantified using 64-multidetector computed tomography, in patients with suspected coronary artery disease ...
Muhammed Bora Demircelik, Omer Caglar Yilmaz, Ozgul Malcok Gurel, Yusuf Selcoki, Inci Asli Atar, Alper Bozkurt, Kayihan Akin, Beyhan Eryonucu   +7 more
doaj   +1 more source

Ectopic fat is linked to prior cardiovascular events in men with HIV. [PDF]

, 2012
Epicardial Adipose Tissue (EAT) has been associated with adverse cardiovascular events in the general population. We studied the association of general adiposity measures (body mass index, waist circumference) and ectopic adipose tissue [visceral adipose
Bagni, Pietro, CARLI, FEDERICA, COCCHI, Stefania, GUARALDI, Giovanni, LIGABUE, Guido, MESCHIARI, MARIANNA, ORLANDO, Gabriella, P. Raggi, Scaglioni, Riccardo, ZONA, Stefano   +9 more
core   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Assessment of coronary artery outward remodeling in consequence of excision of epicardial adipose tissue in Ossabaw swine [PDF]

, 2017
Background Coronary artery disease (CAD) results from the buildup of cholesterol, inflammatory factors, and proliferating smooth muscle cells within a vessel wall. This plaque impedes on the vessel lumen, decreasing the space through which blood can flow,
Coderre, Kelly
core   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, Volume 104, Issue 6, Page 539-555, June 2026.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Chemical Characterization of Toxic Elements in Plastic Utensils: Key Insights and Health Impacts

CLEAN – Soil, Air, Water, Volume 54, Issue 5, May 2026.
Toxic elements in plastic utensils are assessed using portable X‐ray fluorescence and specific migration tests with water and 3% acetic acid as food simulants. Cadmium, lead, arsenic, and mercury are detected in the utensils, and migration results show exceedances of specific migration limits, particularly for lead, mercury, and cadmium. These findings
Elizeu Chiodi Pereira, Lucas Takeshi Shimizu Hossokawa, Isabelle Nogueira Leroux, Aline de Carvalho Elias, Maciel Santos Luz, Kelly Polido Kaneshiro Olympio   +5 more
wiley   +1 more source

Epicardial adipose tissue in patients with heart failure [PDF]

, 2010
Purpose The aim of this study was to evaluate the extent of epicardial adipose tissue (EAT) and its relationship with left ventricular (LV) parameters assessed by cardiovascular magnetic resonance (CMR) in patients with congestive heart failure (CHF) and
Christina Doesch, Dariusch Haghi, Stephan Fluchter, Tim Suselbeck, Stefan O Schoenberg, Henrik Michaely, Borggrefe Martin, Theano Papavassiliu   +7 more
core   +1 more source

Plasma Dilution After Myocardial Ischemia–Reperfusion Injury Promotes Cardiac Repair, Heart Performance, and Recovery of Motor Function and Endurance in Old Mice

Aging Cell, Volume 25, Issue 5, May 2026.
Plasma dilution at 24 h after I/R improved cardiac remodeling, function, and the physical performance of old male and female mice, through lowered markers of inflammation, fibrosis, reduction of cardiomyocytes' apoptosis, increase in their cell‐cycle re‐entry, and healthier profile of newly synthesized proteome, including the determinants of Jak/Stat ...
Joana Marie C. Cruz, Rana Alzalzalee, Hayden Yeung, Zainab Mahmood, Qile Yang, Negar Morshedian, Zachery R. Robinson, Karan R. Malhotra, Michael J. Conboy, Ahmad Reza Mazahery, Jose B. Nevado, Irina M. Conboy   +11 more
wiley   +1 more source

Cardiac steatosis associates with visceral obesity in nondiabetic obese men. [PDF]

, 2013
Background: Liver fat and visceral adiposity are involved in the development of the metabolic syndrome (MetS). Ectopic fat accumulation within and around the heart has been related to increased risk of heart disease.
Adiels, Martin, Granér, Marit, Hakkarainen, Antti, Lauerma, Kirsi, Lundbom, Jesper, Lundbom, Nina, Nieminen, Markku S, Nyman, Kristofer, Pentikäinen, Markku O, Siren, Reijo, Taskinen, Marja-Riitta   +10 more
core   +1 more source