Results 51 to 60 of about 12,022 (265)

Single‐Cell RNA Editing Identifies T Cell ADAR1 as a Key Regulator of Immune Exhaustion and Anti‐PD‐1 Resistance in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA editing analysis identifies ADAR1 as a regulator of dysfunctional T cell states in colorectal cancer. Elevated ADAR1 activity promotes T cell exhaustion and impairs antitumor immunity partly through TGF‐β‐SMAD signaling, contributing to anti‐PD‐1 resistance and highlighting T cell ADAR1 as a potential therapeutic target and biomarker ...
Da Kang   +10 more
wiley   +1 more source

THE EXPERIENCE OF W. RADLOFF SHOULD SERVE AS A MODEL FOR US

open access: yesUluslararası Türk Lehçe Araştırmaları Dergisi, 2017
The book written by Philologist Prof Prof. Dr. Ferit Yusupov, a member of Turkish Language Society’s communication branch, “Сибирские татары. Из сокровищницы духовной культуры. Антология фольклора сибирских татар: дастаны, мунаджаты, баиты. Казань: изд-
Fenzile CEVHEROVA, Gafur SÖNGATOV
doaj   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan   +29 more
wiley   +1 more source

Dialogisme du double sens : l'exemple du Rāghavapāṇḍavīya de Kavirāja

open access: yesÉtudes romanes de Brno, 2015
This article is part of a larger study aiming at showing that Sanskrit poems with multiple meanings, far from being obscure or utterly difficult to understand were quite an important and appreciated genre of Indian literature.
Sylvain Brocquet
doaj  

CAÑAR DESTANINDA GELENEK VE GEÇİŞ TÖRENLERİ BAĞLAMINDA SOSYAL HAYAT

open access: yesMotif Akademi Halkbilimi Dergisi, 2020
Epics are the identities of the nations. It is possible to find the data of religious, political, social and cultural values of a society in epics. The epics of Siberian Turks are very rich in this respect, like the epics of the entire Turkish World ...
Zehra Görkem Duran Gültekin
doaj   +1 more source

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

The Poetic Structure of Silius Italicus' Punica (Books I-V)

open access: yesClassica Cracoviensia, 2019
Poetic Structure of Silius Italicus' Punica (Books I-V) As concerns their poetic structure, the first five books of Silius’ Punica are very differentiated and complicated.
Stanisław Śnieżewski
doaj   +1 more source

Differential Tissue‐Coupled Powering for Battery‐Free Injectable Electroceuticals

open access: yesAdvanced Science, EarlyView.
A thread‐like injectable neural stimulator is powered through differential tissue‐coupled powering (DTCP), which harvests RF‐frequency tissue potentials with an elongated receiver while preserving a injectable cross‐section. The system integrates an ASIC, stimulation electrodes, and a portable transmitter, enabling wireless peripheral nerve stimulation,
Han Wu   +13 more
wiley   +1 more source

Faire événement : l’épopée homérique comme spectacle rituel

open access: yesPallas, 2018
When speaking about Ancient Greek performances, we usually think of dramatic representations. Even though we only have access to the texts of the Iliad and the Odyssey, we are entitled to regard the epics as performances.
Manon Brouillet
doaj   +1 more source

Lyricism of Old Milija's epic poems [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini, 2014
The epic poems of Old Milija are marked by a lyrical organization of the text, which is in the function of depicting the inner life of his heroes. Every now and then, Old Milija breaks the rules of epic poems to dwell upon the inner reflection of the ...
Pitulić Valentina D.
doaj   +1 more source

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