Results 111 to 120 of about 702,111 (308)

Epidemic Intelligence Service (EIS) 2017 annual update [PDF]

Bibliography (EIS Contributions to Public Health Literature: Publications with Authors in the 2014-2016 EIS Classes): p. 15-40.Epidemic Intelligence Service Program, Epidemiology Workforce Branch, Division of Scientific Education and Professional ...

core  

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Determinants of Bird Richness in the Louzishan National Nature Reserve: Effects of Productivity and Habitat Heterogeneity Across Taxonomic and Functional Dimensions

Ecology and Evolution
Human activities are modifying Earth's ecosystems in different ways and at different scales, and conserving multiple aspects of biodiversity has become important for maintaining ecosystem stability.
Xiaocui Ma, Meiting Wang, Shiguang Zhang, Dongmei Wan, Yiting Jiang   +4 more
doaj   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Epidemiology, transmission dynamics and control of SARS: the 2002-2003 epidemic [PDF]

, 2004
This paper reviews current understanding of the epidemiology, transmission dynamics and control of the aetiological agent of severe acute respiratory syndrome (SARS).
Hedley, A, Leung, Gabriel M, Ghani, Azra C, Christophe Fraser, Lam, T, Anderson, RM, Ghani, AC, Lam, TH, Azra C. Ghani, Donnelly, C, Leung, GM, Fraser, C, Ferguson, Neil M, Fraser, Christophe, Donnelly, CA, Hedley, AJ, Christl A. Donnelly, Anderson, Roy M, Ferguson, NM, Riley, Steven, Roy M. Anderson, Leung, G, Hedley, Anthony J, Anthony J. Hedley, Ghani, A, Ferguson, N, Anderson, R, Donnelly, Christl A, Steven Riley, Riley, S, Neil M. Ferguson, Gabriel M. Leung, Tai H. Lam   +32 more
core   +1 more source

Medicines, misinformation and machines: Navigating infodemics in the generative AI era

British Journal of Clinical Pharmacology, EarlyView.
Health information is now widely accessed through smartphones, online searches and increasingly through generative artificial intelligence (AI). These systems create new opportunities for communication, and in some routine contexts, well‐governed AI assistants could reduce exposure to lower quality sources by providing cautious, evidence‐aligned ...
Natansh D. Modi, Lisa M. Kalisch Ellett, Michael D. Wiese, Ashley M. Hopkins   +3 more
wiley   +1 more source

Harnessing the power of artificial intelligence for disease-surveillance purposes

BMC Proceedings
The COVID-19 pandemic accelerated the development of AI-driven tools to improve public health surveillance and outbreak management. While AI programs have shown promise in disease surveillance, they also present issues such as data privacy, prejudice ...
Barbara Tornimbene, Zoila Beatriz Leiva Rioja, John Brownstein, Adam Dunn, Sylvain Faye, Jude Kong, Nada Malou, Clara Nordon, Benjamin Rader, Oliver Morgan   +9 more
doaj   +1 more source

Characterization of Immune Responses to RBD‐SD1 Nanoparticle Vaccines Derived From ACE2‐Capable HKU5‐CoV‐2, NeoCoV, and HKU5 Merbecoviruses

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles presenting HKU5, NeoCoV, and HKU5‐CoV‐2 RBD‐SD1 induced strong, cross‐reactive IgG responses in immunized mice. The surrogate virus neutralization test demonstrated strong activity in sera from homologous vaccination. ABSTRACT Recent discoveries of merbecoviruses such as HKU5, NeoCoV, and HKU5‐CoV‐2 that use angiotensin ...
Peter J. Halfmann, Jeong Soo Lee, Augustine Duffy, Tong Wang, Bingcheng Huang, James Z. Kurdi, Ajay Inampudi, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +11 more
wiley   +1 more source

Informing social media analysis for public health: a cross-sectional survey of professionals

Archives of Public Health
Background During the COVID-19 pandemic, the field of infodemic management has grown in response to urgent global need. Social listening is the first step in managing the infodemic, and many organizations and health systems have implemented processes ...
Becky K. White, Elisabeth Wilhelm, Atsuyoshi Ishizumi, Surangani Abeyesekera, Alhassan Pereira, Brian Yau, Aleksandra Kuzmanovic, Tim Nguyen, Sylvie Briand, Tina D. Purnat   +9 more
doaj   +1 more source