Results 121 to 130 of about 642,453 (316)

Meta-analysis of hybrid immunity to mitigate the risk of Omicron variant reinfection

Frontiers in Public Health
BackgroundHybrid immunity (a combination of natural and vaccine-induced immunity) provides additional immune protection against the coronavirus disease 2019 (COVID-19) reinfection.
Huiling Zheng, Huiling Zheng, Shenggen Wu, Wu Chen, Shaojian Cai, Meirong Zhan, Cailin Chen, Jiawei Lin, Zhonghang Xie, Jianming Ou, Wenjing Ye   +10 more
doaj   +1 more source

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer, Eliza J. McEwin, Zhicheng Wang, Joel Lexchin, Barbara Mintzes   +4 more
wiley   +1 more source

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis, Johanna E. Vriezekolk, Frédérique H. C. Bollen, Dirk E. Schrander, Arnt F. A. Schellekens, Bart J. F. van den Bemt   +5 more
wiley   +1 more source

Informing social media analysis for public health: a cross-sectional survey of professionals

Archives of Public Health
Background During the COVID-19 pandemic, the field of infodemic management has grown in response to urgent global need. Social listening is the first step in managing the infodemic, and many organizations and health systems have implemented processes ...
Becky K. White, Elisabeth Wilhelm, Atsuyoshi Ishizumi, Surangani Abeyesekera, Alhassan Pereira, Brian Yau, Aleksandra Kuzmanovic, Tim Nguyen, Sylvie Briand, Tina D. Purnat   +9 more
doaj   +1 more source

Review of the Epizootic and Epidemic Situation regarding Highly Pathogenic Avian Influenza in Russia and Globally in 2025

Проблемы особо опасных инфекций
In 2025, high epizootic activity of highly pathogenic avian influenza virus (HPAIV) persisted globally, as evidenced by more than 7,000 outbreaks reported in poultry and wild birds across 75 countries, resulting in mortality or culling of birds exceeding
A. I. Enikeeva, A. S. Panova, N. N. Vasiltsova, A. V. Danilenko, K. N. Shadrinova, S. V. Svyatchenko, K. I. Ivanova, G. S. Onkhonova, N. I. Goncharova, T. V. Tregubchak, T. V. Bauer, M. V. Sivay, L. V. Maksimenko, V. Yu. Marchenko   +13 more
doaj   +1 more source

Discrete-Time Household Epidemic Models

We present a general Markovian discrete-time SIR household epidemic model based on time units of a day. The model is flexible in how within-household infection depends upon the number of infectives at a given time and the interactions between global ...
Martin, Niamh, Sirl, David, Ball, Frank, Neal, Peter   +3 more
core   +2 more sources

A stochastic differential equation SIS epidemic model

, 2011
In this paper we extend the classical susceptible-infected-susceptible epidemic model from a deterministic framework to a stochastic one and formulate it as a stochastic differential equation (SDE) for the number of infectious individuals $I(t)$. We then
Hu, L., X. Mao, Greenhalgh, David, D. Greenhalgh, Mao, Xuerong, Gray, Alison, Pan, Jiafeng, A. Gray, L. Hu, J. Pan   +9 more
core   +1 more source

Do consumers and healthcare professionals report the same adverse event differently? A paired analysis of duplicate vaccine safety reports in Norway

British Journal of Clinical Pharmacology, EarlyView.
Aim This study aimed to compare how Norwegian healthcare professionals (HCPs) and consumers reported the same adverse event (AE) following immunization with vaccines against COVID‐19 during the COVID‐19 pandemic. Specifically, we aimed to compare the extent to which HCPs and consumers reported information relevant for assessing the causal relationship ...
Tommy Emil Dzus, Johaina Sarrage, Hilde Samdal, François Montastruc, Elena Rocca   +4 more
wiley   +1 more source

Paeoniflorin Alleviates LPS-Induced Inflammation and Acute Myocardial Injury by Inhibiting PI3K/Akt/ERK-Mediated HIF-1α and TLR4/MyD88/NF-κB Inflammatory Signaling

Mediators of Inflammation
Sepsis-induced myocardial injury (SIMI) greatly increases the mortality rate of sepsis. Although paeoniflorin (PF) has been proven to improve survival in sepsis, the detailed mechanism of PF on SIMI remains elusive.
Xiaowu Guo, Zhiguang Han, Jiahuan Sun, Shupeng Liu, Chuang Zhang, Gengrui Xu, Xiaodan Wang, Qiuhang Song, Hongxia Yang, Aiying Li   +9 more
doaj   +1 more source

Development, Delivery, and Evaluation of the Texas Epidemic Public Health Institute (TEPHI) Infection Control Lecture 200 Series

Antimicrobial Stewardship & Healthcare Epidemiology
Background: The Texas Epidemic Public Health Institute (TEPHI) aims to safeguard public health and bolster the economy by preparing for infectious disease outbreaks.
Kayla Ruch, Anabel Rodriguez, Janelle Rios Janelle Rios   +2 more
doaj   +1 more source