Results 71 to 80 of about 865,518 (384)

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Residual paralysis and its influencing factors among acute flaccid paralysis cases in Jiangxi province from 2012 to 2023: a longitudinal study

Zhongguo gonggong weisheng
ObjectiveTo investigate the residual paralysis in acute flaccid paralysis (AFP) cases and its influencing factors in Jiangxi province from 2012 to 2023, and to provide a reference for the development of strategies to reduce residual paralysis ...
Hongping ZHAO, Lihong LIU, Min ZHENG, Fengyun WU, Shicheng GUO, Jie LIU   +5 more
doaj   +1 more source

An empirical method to estimate the effect of soil on the rate for transmission of damping‐off disease

, 2004
The ability of some soils to suppress soil-borne diseases has been long recognised, but the underlying epidemiological mechanisms by which this occurs are largely unknown.• Using damping-off disease caused by Rhizoctonia solani, spreading through ...
Alabouvette C, Bailey DJ, C. A. Gilligan, Cook RJ, Dwyer G, Garrett KA, Gilligan CA, Gilligan CA, Gilligan CA, Hoper H, J. A. N. Filipe, Jeger MJ, Kleczkowski A, Nisbet RM, Otten W, Pielaat A, van den Bosch F, Van der Plank JE, W. Otten, Whipps JM   +19 more
core   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

The First Outbreak of Dengue Fever in Greater Darfur, Western Sudan

Tropical Medicine and Infectious Disease, 2019
Dengue virus (DENV) is an arthropod-borne virus (arbovirus) transmitted by the Aedes mosquitoes, mainly Aedes aegypti. Dengue fever is a rapidly growing disease with expanding geographical distribution worldwide.
Ayman Ahmed, Adel Elduma, Babiker Magboul, Tarig Higazi, Yousif Ali   +4 more
doaj   +1 more source

The Cost of Uncertainty in Curing Epidemics

, 2018
Motivated by the study of controlling (curing) epidemics, we consider the spread of an SI process on a known graph, where we have a limited budget to use to transition infected nodes back to the susceptible state (i.e., to cure nodes).
Caramanis, Constantine, Hoffmann, Jessica   +1 more
core   +1 more source

Asymmetry of the Ferroelectric Phase Transition in BaTiO3

Advanced Materials, EarlyView.
Phase transitions are typically assumed to behave identically in forward and reverse. This work shows that in the ferroelectric material barium titanate this is not true: heating drives an abrupt, first‐order jump, while cooling gives a smooth, continuous change.
Asaf Hershkovitz, Elangovan Hemaprabha, Rajesh Mandal, Pravin Kavle, Jamil Tanus, Maya Barzilay, Ching‐Che Lin, David Spirito, Semën Gorfman, Bo Wang, Ignacio J. Villar‐García, Neus Domingo, Long‐Qing Chen, Lane W. Martin, Yachin Ivry   +14 more
wiley   +1 more source

Identification of genetic diversity of Bufo gargarizans and Pelophylax nigromaculatus in the three islands of Chongming insights into aquaculture resources protection

Journal of the World Aquaculture Society
Creatures grown on the island are more susceptible to genetic vulnerabilities because of their isolated nature and often limited genetic diversity. Understanding the genetic structure of these populations is crucial for effective conservation strategies,
Yiqiong Cui, Rusong Ding, Youzhong Ding, Yubo Shi, Zhenxing Su, Dian Shen, Min Chen   +6 more
doaj   +1 more source

Evaluation of the Sexually Transmitted Infections Programme among Key and Priority Populations in Primary Healthcare Facilities to Inform a Targeted Response: A Protocol Paper

Methods and Protocols
Primary healthcare facilities lack routine diagnostic screening due to resource limitations and dependence on syndromic management, resulting in an unprecedented prevalence and incidence of sexually transmitted infections (STIs), particularly among key ...
Mohlago Ablonia Seloka, Edith Phalane, Refilwe Nancy Phaswana-Mafuya   +2 more
doaj   +1 more source

Co-circulation of dengue virus serotypes 1 and 3 in the Fatick region of senegal 2018

Frontiers in Virology, 2023
On 10th September 2018, the Syndromic Sentinel Surveillance network that monitors febrile illnesses in all 14 regions of Senegal detected a peak of fever in the Fatick region. On 13 September 2018, 10 samples were sent to the WHO Collaborating Centre for
Cheikh Tidiane Diagne, Idrissa Dieng, Oumar Faye, Cheikh Fall, Mamadou Aliou Barry, Maryam Diarra, Oumar Ndiaye, Marie Henriette Dior Ndione, Mamadou Ndiaye, Boly Diop, Abdoulaye Bousso, Abiboulaye Sall, Gamou Fall, Cheikh Loucoubar, Yamar Ba, Amadou Alpha Sall, Mawlouth Diallo, Ousmane Faye   +17 more
doaj   +1 more source