Results 151 to 160 of about 1,016,517 (356)

Quantitative Antibiogram as a Typing Method for the Prospective Epidemiological Surveillance and Control of MRSA: Comparison with Molecular Typing [PDF]

, 1996
Dominique Blanc, Christiane Pétignat, Philippe Moreillon, Aline Wenger, Jacques Billé, Patrick Francioli   +5 more
openalex   +1 more source

Oxytocin‐Mediate Modulation of Splenic Immunosuppression in Chronic Social Stress Through Neuroendocrine Pathways

Advanced Science, EarlyView.
Chronic social stress elevates oxytocin levels, leading to immunosuppression by enhancing regulatory T‐cell activity and promoting anti‐inflammatory macrophage polarization in the spleen. Blocking oxytocin signaling reverses these effects but worsens stress‐induced behavioral disorders and reduces survival rates. This highlights oxytocin's dual role in
Yi‐Shu Zhang, Hai‐Chao Chen, Jia‐Xin Cao, Si‐Wei Zhou, Yue‐Zhang Ma, Yu‐Hong Jing   +5 more
wiley   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Epidemiologic Methods to Estimate Insufficient Sleep in the US Population. [PDF]

Int J Environ Res Public Health, 2020
Jean-Louis G, Turner AD, Seixas A, Jin P, Rosenthal DM, Liu M, Avirappattu G.   +6 more
europepmc   +1 more source

Development of Multi-Locus Variable Number Tandem Repeat Analysis for Outbreak Detection of Neisseria meningitidis [PDF]

, 2006
Neisseria meningitidis is a major cause of septicemia and meningitis worldwide. Traditional typing methods like pulsed-field gel electrophoresis (PFGE) for identifying outbreaks are subjective and time consuming.
Price, Alicia Anne
core  

Estudos de agregados de doença no espaço-tempo: conceitos, técnicas e desafios

Cadernos de Saúde Pública
Os estudos de agregados espaço-temporais têm sido freqüentemente utilizados em epidemiologia e saúde pública nas últimas décadas, muitas vezes sem a adequada compreensão de seus limites e potencialidades.
Guilherme L. Werneck, Claudio J. Struchiner   +1 more
doaj  

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non‐small Cell Lung Cancer

Advanced Science, EarlyView.
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin, Yongbiao Huang, Bin Li, Yuan Wang, Yan Li, Zhirui Chen, Zhe Tang, Chaofan Liu, Lei Zhang, Xianglin Yuan, Jianbo Tian, Bo Liu   +11 more
wiley   +1 more source

Tissue mosaicism, FMR1 expression and intellectual functioning in males with fragile X syndrome

American Journal of Medical Genetics Part A, Volume 191, Issue 2, Page 357-369, February 2023., 2023
Abstract Fragile X syndrome (FXS) is caused by hypermethylation of the FMR1 promoter due to the full mutation expansion (full mutation [FM]: CGG ≥ 200 repeats) and silencing of FMR1. Assessment of mosaicism for active‐unmethylated alleles has prognostic utility.
Emma K. Baker, Marta Arpone, Minh Bui, Claudine M. Kraan, Ling Ling, David Francis, Mathew F. Hunter, Carolyn Rogers, Michael J. Field, Lorena Santa María, Víctor Faundes, Bianca Curotto, Paulina Morales, Cesar Trigo, Isabel Salas, Angelica M. Alliende, David J. Amor, David E. Godler   +17 more
wiley   +1 more source

Data informed epidemiological-behavioural modelling [PDF]

arXiv
Augmenting classical epidemiological models with information from the social sciences helps unveil the interplay between contagion dynamics and social responses. However, multidisciplinary integration of social analysis and epidemiological modelling is often challenging, due to scarcity of vast and reliable data sources and because ad hoc modelling ...
arxiv  

Accurate reporting of adherence to inhaled therapies in adults with cystic fibrosis: methods to calculate normative adherence

Patient Preference and Adherence, 2016
Zhe Hui Hoo,1,2 Rachael Curley,1,2 Michael J Campbell,1 Stephen J Walters,1 Daniel Hind,3 Martin J Wildman1,2 1School of Health and Related Research (ScHARR), University of Sheffield, 2Sheffield Adult Cystic Fibrosis Centre, Northern General ...
Hoo ZH, Curley R, Campbell MJ, Walters SJ, Hind D, Wildman MJ   +5 more
doaj