Results 51 to 60 of about 196,202 (217)

Real-time Estimates in Early Detection of SARS

Emerging Infectious Diseases, 2006
We propose a Bayesian statistical framework for estimating the reproduction number R early in an epidemic. This method allows for the yet-unrecorded secondary cases if the estimate is obtained before the epidemic has ended. We applied our approach to the
Simon Cauchemez, Pierre-Yves Boëlle, Christl A. Donnelly, Neil M Ferguson, Guy Thomas, Gabriel M. Leung, Anthony J Hedley, Roy M. Anderson, Alain-Jacques Valleron   +8 more
doaj   +1 more source

Dementia Incidence in Individuals With Parkinson's Disease in the Framingham Heart Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Limited information exists on incident dementia in individuals with Parkinson's disease (PD) in US community‐based samples. We examined cognitive statuses and PD diagnoses of 183 individuals in the Framingham Heart Study (FHS) to establish incident dementia, mortality rates, associations with sex, age at PD onset, and education level.
Joshi Dookhy, Michael Cummings, Eden Price, Yulin Liu, Santiago Gutierrez‐Gomez, Sarah O'Shea, Samuel Frank, Rhoda Au, Ashita S. Gurnani, Ting Fang Alvin Ang, Jesse Mez, Ludy C. Shih   +11 more
wiley   +1 more source

For a General Theory of Health: preliminary epistemological and anthropological notes

Cadernos de Saúde Pública
In order to conduct a preliminary evaluation of the conditions allowing for a General Theory of Health, the author explores two important structural dimensions of the scientific health field: the socio-anthropological dimension and the epistemological ...
Naomar de Almeida Filho
doaj  

An empirical method to cluster objective nebulizer adherence data among adults with cystic fibrosis

Patient Preference and Adherence, 2017
Zhe H Hoo,1,2 Michael J Campbell,1 Rachael Curley,1,2 Martin J Wildman1,2 1School of Health and Related Research (ScHARR), University of Sheffield, 2Sheffield Adult Cystic Fibrosis Centre, Northern General Hospital, Sheffield, UK Background: The ...
Hoo ZH, Campbell MJ, Curley R, Wildman MJ   +3 more
doaj  

The Number Needed to Treat: 25 Years of Trials and Tribulations in Clinical Research

Rambam Maimonides Medical Journal, 2015
The number needed to treat (NNT) is a simple measure of a treatment’s impact, increasingly reported in randomized trials and observational studies, but often incorrectly calculated in studies involving varying follow-up times. We discuss the NNT in these
Samy Suissa
doaj   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Exploring analytical pathways for climate change as a threat multiplier

Environmental Research Letters
Climate change has been widely conceptualized as a threat multiplier of pre-existing disadvantage, yet quantitative research has lacked a structured framework for empirically testing how climate-related exposures amplify disadvantage–outcome ...
Nadav L Sprague, Diana Hernández, Christine C Ekenga, Charles C Branas, Pam Factor-Litvak   +4 more
doaj   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Método de captura e recaptura: nova metodologia para pesquisas epidemiológicas

Revista de Saúde Pública
O método de captura e recaptura, embora não seja novo, tem sido pouco usado em estudos epidemiológicos. Trata-se de método bem adaptável e adequado para estudar populações incomuns ou esquivas, como usuários de drogas endovenosas.
John Dunn, Sérgio Baxter Andreoli
doaj  

Study designs: Part 3 - Analytical observational studies

Perspectives in Clinical Research, 2019
In analytical observational studies, researchers try to establish an association between exposure(s) and outcome(s). Depending on the direction of enquiry, these studies can be directed forwards (cohort studies) or backwards (case–control studies).
Priya Ranganathan, Rakesh Aggarwal
doaj   +1 more source