Results 131 to 140 of about 448,594 (314)

Epidemiological aspects of surgical site infections in an income country. The case of regional hospital center, Borgou (Benin) [PDF]

, 2017
Background: Surgical site infection is frustrating for the care team and depressing for the patient. Objective: To determine the epidemiological aspects of surgical site infections in regional hospital, Borgou.
Akpata, Robert, Allodé S., Alexandre, And Mêhinto K., Delphin, Atakpa S., Felix, Dadjo A., Yves, Fatigba O., Holden, Hodonou M., Adrien, Hounkponou-ahouingnan, Fanny, Mensah Ad, Emile, Tamou-sambo, Bio, Tobome, SEMEVO ROMARIC   +10 more
core  

Selenoprotein H Functions as a PPARα Coactivator to Link Selenium Homeostasis to Hepatic Lipid Metabolism and Protect against Steatohepatitis

Advanced Science, EarlyView.
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang, Yuchen Wang, Binbin Li, Xin Li, Chenyu Liu, Yanhao Chen, Cheng Tian, Dongmei Wang, Xiaosong Gu, Chunping Jiang, Yuda Wei, Qiurong Ding   +11 more
wiley   +1 more source

Epidemiological Pattern of Diseases Requiring Hospitalization in Patients Attending Health Centers Participating in Tehran Health Insurance Organization Network in 2005-2014

مجله اپیدمیولوژی ایران, 2018
Background and Objectives: Evaluation of the epidemiologic pattern of diseases requiring hospitalization is one of the effective factors in better management of hospitals, which can provide health managers and planners with a realistic and appropriate ...
MR Jamali, A Shojaee, M Ghanadi, J Jamali   +3 more
doaj  

Impact of COVID-19 on the epidemiology of respiratory viruses in southern Brazil

Revista de Epidemiologia e Controle de Infecção
Background and objectives: During the SARS-CoV-2 pandemic, reduction in detection of other Respiratory Viruses (RV) was observed. Epidemiological studies are needed to understand the impact of the pandemic on the circulation of RV.
Fernanda Pereira da Silva Carpeggiani, Thiago Menezes Cézar, Tatiana Schäffer Gregianini, Felipe Grillo Pinheiro, Letícia Garay Martins, Ana Beatriz Gorini da Veiga   +5 more
doaj   +1 more source

[SARS-CoV‑2 incidental findings among Hamburg deaths: an epidemiological monitoring during the dynamic infection event in spring 2020]. [PDF]

Rechtsmedizin (Berl), 2021
Klein A, Langenwalder F, Heinrich F, Meißner K, Schröder AS, Püschel K, Ondruschka B, Lütgehetmann M, Heinemann A.   +8 more
europepmc   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Molecular Detection of Mycobacterium leprae and the Process of Infection and Illness in Contacts of Leprosy Patients: A Systematic Review

Tropical Medicine and Infectious Disease
Various techniques have been used for the molecular identification of Mycobacterium leprae (M. leprae). The aim of this review was to identify the relationship between the molecular presence of M.
Sarah Lamas Vidal, Lavínia Cássia Ferreira Batista, Daniele dos Santos Lages, Bruna Eduarda Bortolomai, Isabela de Caux Bueno, Eyleen Nabyla Alvarenga Niitsuma, Nathan Guilherme de Oliveira, Ida Maria Foschiani Dias Baptista, Francisco Carlos Félix Lana   +8 more
doaj   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Evolving global patterns of congenital heart anomalies from 1990 to 2021

Archives of Medical Science
Introduction Congenital heart anomalies (CHAs) remain a significant global health issue for children, evidenced by persistent disparities in healthcare access across different socio-demographic index (SDI) regions and genders, despite slight decreases in
Enhui Yang, Hao Lin, Yuansi Zhang, Yu Zhang, Feng Chen   +4 more
doaj   +1 more source

User oriented access to secure biomedical resources through the grid [PDF]

, 2006
The life science domain is typified by heterogeneous data sets that are evolving at an exponential rate. Numerous post-genomic databases and areas of post-genomic life science research have been established and are being actively explored. Whilst many of
Ajayi, O., Jiang, J., Sinnott, R.O., Stell, A.J., Watt, J.   +4 more
core   +3 more sources