Results 61 to 70 of about 448,594 (314)

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

The effect of changing diagnostic method from culture to PCR on the number of episodes of human campylobacteriosis in Denmark: a retrospective study (2015–2022)

Microbiology Spectrum
We investigated whether the introduction of polymerase chain reaction (PCR) to replace culture as the primary diagnostic method for Campylobacter species in the Danish Departments of Clinical Microbiology (DCMs) was associated with a systematic change in
Guido Benedetti, Christian Holm Hansen, Anna Tølbøll Svendsen, Katrine Grimstrup Joensen, Gitte Sørensen, Anne Line Engsbro, Mia Torpdahl, Eva Møller Nielsen, Steen Ethelberg   +8 more
doaj   +1 more source

Epidemiological monitoring of avian influenza in the Republic of Crimea in 2019–2020

Ветеринария сегодня, 2021
The paper presents results of avian influenza epidemiological monitoring in the Republic of Crimea in 2019–2020. The attention was focused on the study of water basins of the Azov and Black Seas, the Sivash Lagoon and freshwater lakes in the Feodosia ...
D. V. Gadzevich, S. I. Danylchenko, N. V. Vorotilova, M. A. Pasunkina, V. A. Uppe, V. N. Irza, M. S. Volkov, N. G. Zinyakov   +7 more
doaj   +1 more source

[Epidemiological monitoring in salmonellosis].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1987
The use of a model DZ-26 computer for the current analysis of salmonellosis and for processing laboratory data is analyzed.
P A, Rakitin, V A, Kichigin
openaire   +1 more source

Epidemiological monitoring: Methods for analysing routinely-collected data

Science of The Total Environment, 1984
Morbidity and mortality statistics are routinely collected in many countries. These data may be arranged in a number of ways, for example, classified by area of residence, or occupation of the person concerned, or by the time-period during which the relevant event occurred.
Inskip, H, Beral, V, Fraser, P, Haskey, J   +3 more
openaire   +2 more sources

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Investigation of congenital syphilis cases: tool for surveillance, permanent education and management

DST, 2021
Introduction: Even though syphilis is an easily detectable and treatable disease, it is still considered a major public health problem, which may lead to Congenital Syphilis (CS).
Kamilla Cabral Kosa, Fábia Lisboa de Souza, Marcella Martins Alves Teofilo, Yasmin Nascimento Farias, Márcia Santana, Ana Lúcia Fontes Eppinghaus, Antônio José Leal Costa   +6 more
doaj  

Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008 [PDF]

, 2012
A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putative cases, 56 laboratory-confirmed cases, and 37 deaths (CFR = 25%).
A Grolla, A MacNeil, A Tuffs, AJ Georges, AM Casillas, B Jeffs, B Le Guenno, Benjamin Jeffs, BS Hewlett, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DH Smith, DL Heymann, E Mupere, ED Johnson, EM Leroy, EM Leroy, Esther Sterk, GA Martini, GA Martini, JL Conrad, Joseph Wamala, JS Gear, JS Towner, Julius Lutwama, K Kibadi, K Mupapa, K Mupapa, KJ Davis, M Borchert, M Bray, M Bray, MA Bwaka, Malcolm Gracie Semple, Maria D. Van Kerkhove, Matthias Borchert, ME Miranda, Michel Van Herp, MJ Bonnet, Natasha Howard, NK Jaax, P Formenty, P Formenty, P Francesconi, P Roddy, P Roddy, Paul Roddy, PE Rollin, Pedro Pablo Palma, PH Sureau, R Colebunders, R Ndambi, R Siegert, RC Baron, Robert Colebunders, RT Emond, S Becker, SF Dowell, SP Fisher-Hoch, SR Zaki, TH Roels, U Stroher, Y Kalongi, Zabulon Yoti   +66 more
core   +3 more sources