Results 91 to 100 of about 612,057 (268)

Impact of genetic risk and lifestyles on cardiovascular disease-free and total life expectancy: a cohort study

Genome Medicine
Background Understanding the role of genetic risk and lifestyles on life expectancy (LE) without cardiovascular disease (CVD) and total LE may help optimize healthy aging strategies after taking genetic background into account. Methods The China Kadoorie
Dong Sun, Qiufen Sun, Yinqi Ding, Canqing Yu, Dianjianyi Sun, Yuanjie Pang, Pei Pei, Ling Yang, Iona Y. Millwood, Robin G. Walters, Huaidong Du, Jun Zhang, Dan Schmidt, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv, the China Kadoorie Biobank Collaborative Group   +17 more
doaj   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi, Sola Al Ghazal, Salem Hannoun, Medhat A. Siddik, Nour M. Najjar, Jim Dagher, Joseph Abboud, Myriam G. Semaan, Samia J. Khoury   +8 more
wiley   +1 more source

Assessing effective treatment coverage for depression

The Lancet Regional Health. Europe, 2022
Giovanni de Girolamo, Dan J. Stein
doaj   +1 more source

Advancing Stroke Clinical Trials Using Community Engagement and Implementation Science Approaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Stroke clinical trials are essential for advancing stroke care but can face challenges with recruitment, retention, clinical relevance, and translation into real‐world practice. We propose that integrating community engagement and implementation science approaches into stroke trials can help address these needs.
Lesli E. Skolarus, Devin L. Brown, Bernadette Boden‐Albala   +2 more
wiley   +1 more source

Spatial analysis of the epidemiological risk of leprosy in the municipalities of Minas Gerais. [PDF]

PLoS Negl Trop Dis, 2023
Bueno IC, Lages DDS, Lana FCF.
europepmc   +1 more source

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Integral Assessment of the Epidemiological Risk of Genetic Lineages of Mycobacterium tuberculosis within the Genomic Epidemiological Surveillance System

Acta Biomedica Scientifica
Introduction. The spread of drug-resistant tuberculosis necessitates the implementation of novel analytical approaches for assessing epidemiological risks using wholegenome sequencing (WGS) data.Objective.
V. V. Sinkov, O. B. Ogarkov, S. N. Zhdanova, E. D. Savilov   +3 more
doaj   +1 more source

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif, Diane Demailly, Gabriella A. Horvàth, Juan Dario Ortigoza Escobar, Nathalie Dorison, Mayté Castro Jiménez, Cécile A. Hubsch, Thomas Wirth, Gun‐Marie Hariz, Sophie Huby, Morgan Dornadic, Zohra Souei, Muhammad Mushhood Ur Rehman, Simone Hemm, Mehdi Boulaymen, Eduardo M. Moraud, Jocelyne Bloch, Xavier Vasques   +17 more
wiley   +1 more source

Retrospective study of the epidemiological risk and serological diagnosis of human babesiosis in Asturias, Northwestern Spain. [PDF]

Parasit Vectors, 2023
Montero E, Folgueras M, Rodriguez-Pérez M, Pérez-Ls L, Díaz-Arias J, Meana M, Revuelta B, Haapasalo K, Collazos J, Asensi V, Gonzalez LM.   +10 more
europepmc   +1 more source

Long-term cardiovascular risk after severe exacerbation of COPD: a population-based cohort study

ERJ Open Research
Background Exacerbation of COPD (ECOPD) has been linked to increased cardiovascular disease (CVD) risk within the first year, yet longer term risk is unclear. We aimed to investigate the short-term and long-term CVD risks after severe ECOPD.
Yinqi Ding, Jingcen Hu, Canqing Yu, Dianjianyi Sun, Pei Pei, Ling Yang, Yiping Chen, Huaidong Du, Zengzhi Zhang, Maxim Barnard, Junshi Chen, Zhengming Chen, Liming Li, Jun Lv   +13 more
doaj   +1 more source