Results 71 to 80 of about 1,174,473 (308)

Use of evidence to support healthy public policy: a policy effectiveness-feasibility loop [PDF]

, 2012
Public policy plays a key role in improving population health and in the control of diseases, including non-communicable diseases. However, an evidence-based approach to formulating healthy public policy has been difficult to implement, partly on ...
Ahmad, B, Ben Romdhane, H, Bowman, S, Capewell, S, Critchley, J, Fouad, F, Husseini, A, Khatib, R, Maziak, W, Phillimore, P, Shoaibi, A, Unal, B, Unwin, N, Zaman, S   +13 more
core   +2 more sources

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Abundance, Diversity and Phenology of Mosquito Larvae in a Highly Anthropized Wetland: Health and Management Implications of Gándaras de Budiño (NW Spain)

Ecology and Evolution
Because of their role as vectors of diseases, the presence of mosquitoes in wetlands often discourages their protection and conservation. The Gándaras de Budiño (Galicia, northwestern Spain) is a natural wetland highly damaged by the activity of a large ...
Yasmina Martínez‐Barciela, Alejandro Polina, Josefina Garrido   +2 more
doaj   +1 more source

Serum markers of bone fragility in type-2 diabetes mellitus [PDF]

, 2019
Patients with type-2 diabetes mellitus (T2DM) have normal or increased bone mineral density (BMD) but despite that, they are characterized by an increased hip and vertebral fracture risk that involves the alteration of bone quality and not the reduction ...
Dănciulescu Miulescu, Rucsandra, Guja, Loreta, Ochiana, Lavinia Claudia, Ungurianu, Anca, Șeremet, Oana Cristina, Ștefănescu, Emil   +5 more
core   +1 more source

Investigation of a Q fever outbreak in a Scottish co-located slaughterhouse and cutting plant [PDF]

, 2010
Outbreaks of Q fever are rare in the UK. In 2006, the largest outbreak of Q fever in Scotland occurred at a co-located slaughterhouse and cutting plant with 110 cases.
Australian Government, British Thoracic Society Standards of Care Committee, Camacho, Chiu, Cutler, Derrick, Fenollar, Hawker, Health Protection Agency, Kermode, Marmion, Maurin, McCaughey, Pollock, Raoult, Raoult, Shapiro, Smith, Thomas, Van Woerden, Waag, Wildman   +21 more
core   +1 more source

[Risk society and epidemiological risk].

Cadernos de saude publica, 2007
The concept of risk entails a broad discussion, ranging from a more general approach, seeking to contextualize it in the dynamic of societal change, to a more specific approach in the field of health, particularly in epidemiological studies on associations.
Olinda do Carmo, Luiz, Amélia, Cohn
openaire   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source