Results 111 to 120 of about 242,492 (291)

Disease and Development Revisited [PDF]

In a recent paper, Acemoglu and Johnson (2007) argue that the large increases in population health witnessed in the 20th century may have lowered income levels.
David Canning, David E. Bloom, Gunther Fink   +2 more
core  

Fitting stochastic epidemic models to gene genealogies using linear noise approximation [PDF]

, 2019
Phylodynamics is a set of population genetics tools that aim at reconstructing demographic history of a population based on molecular sequences of individuals sampled from the population of interest.
Bedford, Trevor, Dudas, Gytis, Minin, Vladimir N., Tang, Mingwei   +3 more
core   +1 more source

Understanding Aging During the Epidemiologic Transition [PDF]

, 2013
The Epidemiologic Transition can help us understand a fundamental puzzle about aging. The puzzle stems from two seemingly contradictory facts. The first fact is that death rates from noninfectious degenerative maladies – the so-called diseases of aging – increase as people age.
openaire   +1 more source

Facilitating Expedited Drug Approval—the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, EarlyView.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

Long-term evolution of the burden of HIV/AIDS in older adults: a global burden of disease analysis in individuals aged ≥75 years in G7 countries

Frontiers in Public Health
BackgroundWith the widespread implementation of antiretroviral therapy (ART), human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) has gradually transitioned from a highly fatal infectious disease to a manageable chronic condition ...
Ruizhuang Sun, Yan Jiang, Yan Jiang, Yan Jiang, Yingyu Yan, Tingxia Zhou, Chonghui Xu, Jingting Wang, Long Ye, Jun Meng, Jun Meng   +10 more
doaj   +1 more source

Phylogenetic analysis accounting for age-dependent death and sampling with applications to epidemics

, 2013
The reconstruction of phylogenetic trees based on viral genetic sequence data sequentially sampled from an epidemic provides estimates of the past transmission dynamics, by fitting epidemiological models to these trees.
Alexander, Helen K., Lambert, Amaury, Stadler, Tanja   +2 more
core  

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

The Phenomenon of Epidemiological Transition in Health and the Necessity to Update

NMO Journal
The epidemiological transition is a global shift from communicable diseases to non-communicable diseases and injuries, impacting health and demographic indicators.
Anjali Modi, Rhythm Panchani, Bhautik Modi, Arvind Asthana   +3 more
doaj   +1 more source

Epidemiological Transition and Strategies for the Control of Hepatitis A in Serbia. [PDF]

Viruses, 2023
Medić S, Anastassopoulou C, Pustahija T, Petrović V, Dragnić N, Boufidou F, Tsakris A, Šaponjić V.   +7 more
europepmc   +1 more source